| Firefly luminescence: a historical perspective and recent developments H Fraga Photochemical & Photobiological Sciences 7 (2), 146-158, 2008 | 275 | 2008 |
| Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications BR Branchini, DM Ablamsky, MH Murtiashaw, L Uzasci, H Fraga, ... Analytical biochemistry 361 (2), 253-262, 2007 | 215 | 2007 |
| ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle DM Smith, H Fraga, C Reis, G Kafri, AL Goldberg Cell 144 (4), 526-538, 2011 | 209 | 2011 |
| Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector H Fraga, D Fernandes, R Fontes, JCG Esteves da Silva The FEBS journal 272 (20), 5206-5216, 2005 | 96 | 2005 |
| Firefly luciferase produces hydrogen peroxide as a coproduct in dehydroluciferyl adenylate formation H Fraga, D Fernandes, J Novotny, R Fontes, JCG Esteves da Silva ChemBioChem 7 (6), 929-935, 2006 | 74 | 2006 |
| Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors J Felix, K Weinhäupl, C Chipot, F Dehez, A Hessel, DF Gauto, C Morlot, ... Science advances 5 (9), eaaw3818, 2019 | 53 | 2019 |
| Identification of luciferyl adenylate and luciferyl coenzyme a synthesized by firefly luciferase H Fraga, JCG Esteves da Silva, R Fontes ChemBioChem 5 (1), 110-115, 2004 | 49 | 2004 |
| Pyrophosphate and tripolyphosphate affect firefly luciferase luminescence because they act as substrates and not as allosteric effectors R Fontes, D Fernandes, F Peralta, H Fraga, I Maio, JCG Esteves da Silva The FEBS journal 275 (7), 1500-1509, 2008 | 46 | 2008 |
| Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific 1H–13C Labeling and Fast Magic-Angle Spinning NMR DF Gauto, P Macek, A Barducci, H Fraga, A Hessel, T Terauchi, D Gajan, ... Journal of the American Chemical Society 141 (28), 11183-11195, 2019 | 43 | 2019 |
| The antibiotic cyclomarin blocks arginine-phosphate–induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis K Weinhäupl, M Brennich, U Kazmaier, J Lelievre, L Ballell, A Goldberg, ... Journal of Biological Chemistry 293 (22), 8379-8393, 2018 | 40 | 2018 |
| Solid‐state NMR H–N–(C)–H and H–N–C–C 3D/4D correlation experiments for resonance assignment of large proteins H Fraga, CA Arnaud, DF Gauto, M Audin, V Kurauskas, P Macek, ... ChemPhysChem 18 (19), 2697-2703, 2017 | 39 | 2017 |
| Enzymatic synthesis of mono and dinucleoside polyphosphates H Fraga, R Fontes Biochimica et Biophysica Acta (BBA)-General Subjects 1810 (12), 1195-1204, 2011 | 34 | 2011 |
| FH8 – a small EF‐hand protein from Fasciola hepatica H Fraga, TQ Faria, F Pinto, A Almeida, RMM Brito, AM Damas The FEBS journal 277 (24), 5072-5085, 2010 | 30 | 2010 |
| Association between foldability and aggregation propensity in small disulfide-rich proteins H Fraga, R Grana-Montes, R Illa, G Covaleda, S Ventura Antioxidants & redox signaling 21 (3), 368-383, 2014 | 28 | 2014 |
| Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity A Mota, P Silva, D Neves, C Lemos, C Calhau, D Torres, F Martel, ... Brazilian Journal of Medical and Biological Research 41, 600-609, 2008 | 27 | 2008 |
| Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis H Fraga, B Rodriguez, A Bardera, C Cid, T Akopian, O Kandror, A Park, ... Analytical biochemistry 567, 30-37, 2019 | 23 | 2019 |
| The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19 H Fraga, JJ Bech-Serra, F Canals, G Ortega, O Millet, S Ventura Journal of Biological Chemistry 289 (14), 9852-9864, 2014 | 21 | 2014 |
| Functional control of a 0.5 MDa TET aminopeptidase by a flexible loop revealed by MAS NMR DF Gauto, P Macek, D Malinverni, H Fraga, M Paloni, I Sučec, A Hessel, ... Nature communications 13 (1), 1927, 2022 | 20 | 2022 |
| Disulfide driven folding for a conditionally disordered protein H Fraga, J Pujols, M Gil-Garcia, A Roque, G Bernardo-Seisdedos, ... Scientific reports 7 (1), 16994, 2017 | 17 | 2017 |
| Chemical synthesis and firefly luciferase produced dehydroluciferyl-coenzyme A H Fraga, JCGE da Silva, R Fontes Tetrahedron letters 45 (10), 2117-2120, 2004 | 17 | 2004 |
