Xinlai Cheng
Xinlai Cheng
確認したメール アドレス: pharmchem.uni-frankfurt.de
タイトル
引用先
引用先
A TrxR inhibiting gold (I) NHC complex induces apoptosis through ASK1-p38-MAPK signaling in pancreatic cancer cells
X Cheng, P Holenya, S Can, H Alborzinia, R Rubbiani, I Ott, S Wölfl
Molecular cancer 13 (1), 1-15, 2014
882014
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic …
S Nam, W Wen, A Schroeder, A Herrmann, H Yu, X Cheng, KH Merz, ...
Molecular oncology 7 (3), 369-378, 2013
802013
Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling
S Nam, A Scuto, F Yang, WY Chen, S Park, HS Yoo, H Konig, R Bhatia, ...
Molecular oncology 6 (3), 276-283, 2012
762012
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells
S Su, X Cheng, M Wink
Phytomedicine 22 (2), 301-307, 2015
432015
Detailed analysis of pro-apoptotic signaling and metabolic adaptation triggered by a N-heterocyclic carbene–gold(i) complex
P Holenya, S Can, R Rubbiani, H Alborzinia, A Jünger, X Cheng, I Ott, ...
Metallomics 6 (9), 1591-1601, 2014
432014
Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists
H Alborzinia, H Schmidt-Glenewinkel, I Ilkavets, K Breitkopf-Heinlein, ...
Journal of cell science 126 (1), 117-127, 2013
432013
Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats
N Heshmati, X Cheng, G Eisenbrand, G Fricker
Journal of pharmaceutical sciences 102 (10), 3792-3799, 2013
412013
Synthesis and cytotoxicity of novel indirubin-5-carboxamides
X Cheng, P Rasqué, S Vatter, KH Merz, G Eisenbrand
Bioorganic & medicinal chemistry 18 (12), 4509-4515, 2010
372010
7, 7′-diazaindirubin—a small molecule inhibitor of casein kinase 2 in vitro and in cells
X Cheng, KH Merz, S Vatter, J Christ, S Wölfl, G Eisenbrand
Bioorganic & medicinal chemistry 22 (1), 247-255, 2014
352014
Liver-kidney-on-chip to study toxicity of drug metabolites
J Theobald, A Ghanem, P Wallisch, AA Banaeiyan, MA Andrade-Navarro, ...
ACS Biomaterials Science & Engineering 4 (1), 78-89, 2018
342018
Indirubin derivatives modulate TGFβ/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads
X Cheng, H Alborzinia, KH Merz, H Steinbeisser, R Mrowka, C Scholl, ...
Chemistry & biology 19 (11), 1423-1436, 2012
322012
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
X Cheng, JY Kim, S Ghafoory, T Duvaci, R Rafiee, J Theobald, ...
Molecular oncology 10 (6), 806-824, 2016
312016
Essential role of mitochondrial Stat3 in p38 MAPK mediated apoptosis under oxidative stress
X Cheng, C Peuckert, S Wölfl
Scientific reports 7 (1), 1-11, 2017
242017
Fluorescent organometallic rhodium (I) and ruthenium (II) metallodrugs with 4-ethylthio-1, 8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction
W Streciwilk, A Terenzi, X Cheng, L Hager, Y Dabiri, P Prochnow, ...
European journal of medicinal chemistry 156, 148-161, 2018
212018
Identification of a water-soluble indirubin derivative as potent inhibitor of insulin-like growth factor 1 receptor through structural modification of the parent natural molecule
X Cheng, KH Merz, S Vatter, J Zeller, S Muehlbeyer, A Thommet, J Christ, ...
Journal of medicinal chemistry 60 (12), 4949-4962, 2017
202017
The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells
Y Dabiri, S Kalman, CM Gürth, JY Kim, V Mayer, X Cheng
Scientific reports 7 (1), 1-12, 2017
182017
Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis
AR Göhring, S Reuter, JH Clement, X Cheng, J Theobald, S Wölfl, ...
PloS one 12 (4), e0174912, 2017
182017
Cytotoxicity of arctigenin and matairesinol against the T‐cell lymphoma cell line CCRF‐CEM
S Su, X Cheng, M Wink
Journal of Pharmacy and Pharmacology 67 (9), 1316-1323, 2015
182015
The role of indirubins in inflammation and associated tumorigenesis
X Cheng, KH Merz
Drug Discovery from Mother Nature, 269-290, 2016
172016
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self‐emulsifying drug delivery systems
N Heshmati, X Cheng, E Dapat, P Sassene, G Eisenbrand, G Fricker, ...
Journal of Pharmacy and Pharmacology 66 (11), 1567-1575, 2014
172014
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