The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes M Christensen, K Andersson, P Dalén, RA Mirghani, GJ Muirhead, ... Clinical Pharmacology & Therapeutics 73 (6), 517-528, 2003 | 220 | 2003 |
4β-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians U Diczfalusy, J Miura, HK Roh, RA Mirghani, J Sayi, H Larsson, KG Bodin, ... Pharmacogenetics and genomics 18 (3), 201-208, 2008 | 169 | 2008 |
Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer H Green, P Söderkvist, P Rosenberg, RA Mirghani, P Rymark, ... Basic & clinical pharmacology & toxicology 104 (2), 130-137, 2009 | 165 | 2009 |
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population RA Mirghani, J Sayi, E Aklillu, A Allqvist, M Jande, A Wennerholm, ... Pharmacogenetics and genomics 16 (9), 637-645, 2006 | 93 | 2006 |
Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography RA Mirghani, Ö Ericsson, J Cook, P Yu, LL Gustafsson Journal of Chromatography B: Biomedical Sciences and Applications 754 (1), 57-64, 2001 | 62 | 2001 |
The roles of cytochrome P450 3A4 and lA2 in the 3‐hydroxylation of quinine in vivo RA Mirghani, U Hellgren, PA Westerberg, O Ericsson, L Bertilsson, ... Clinical Pharmacology & Therapeutics 66 (5), 454-460, 1999 | 53 | 1999 |
CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity H Gréen, K Skoglund, F Rommel, RA Mirghani, K Lotfi European journal of clinical pharmacology 66, 383-386, 2010 | 50 | 2010 |
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers A Allqvist, J Miura, L Bertilsson, RA Mirghani European journal of clinical pharmacology 63, 173-179, 2007 | 48 | 2007 |
Metabolism and elimination of quinine in healthy volunteers RA Mirghani, U Hellgren, L Bertilsson, LL Gustafsson, Ö Ericsson European journal of clinical pharmacology 59, 423-427, 2003 | 48 | 2003 |
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man RA Mirghani, Ö Ericsson, G Tybring, LL Gustafsson, L Bertilsson European journal of clinical pharmacology 59, 23-28, 2003 | 48 | 2003 |
Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria II Abdelrahim, I Adam, G Elghazali, LL Gustafsson, MI Elbashir, ... Journal of Clinical pharmacy and Therapeutics 32 (1), 15-19, 2007 | 45 | 2007 |
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway RA Mirghani, Ü Yasar, T Zheng, JM Cook, LL Gustafsson, G Tybring, ... Drug metabolism and disposition 30 (12), 1368-1371, 2002 | 41 | 2002 |
Frequency of rs731236 (Taql), rs2228570 (Fok1) of Vitamin-D Receptor (VDR) gene in Emirati healthy population E Osman, F Al Anouti, A Haq, R Mirgani, H Al Safar Meta gene 6, 49-52, 2015 | 32 | 2015 |
High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper Å Jansson, LL Gustafsson, RA Mirghani Journal of Chromatography B 795 (1), 151-156, 2003 | 32 | 2003 |
Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of α-and 4-hydroxy metabolites in healthy subjects A Wennerholm, A Allqvist, JO Svensson, LL Gustafsson, RA Mirghani, ... European journal of clinical pharmacology 61, 113-118, 2005 | 28 | 2005 |
Simultaneous quantification of alprazolam, 4-and α-hydroxyalprazolam in plasma samples using liquid chromatography mass spectrometry A Allqvist, A Wennerholm, JO Svensson, RA Mirghani Journal of Chromatography B 814 (1), 127-131, 2005 | 25 | 2005 |
Distribution of the major cytochrome P450 (CYP) 2C9 genetic variants in a Saudi population RA Mirghani, G Chowdhary, G Elghazali Basic & clinical pharmacology & toxicology 109 (2), 111-114, 2011 | 24 | 2011 |
Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat H Xie, P Afsharian, Y Terelius, RA Mirghani, Ü Yasar, AL Hagbjörk, ... Xenobiotica 35 (3), 239-251, 2005 | 19 | 2005 |
High-performance liquid chromatographic method for the determination of the major quinine metabolite, 3-hydroxyquinine, in plasma and urine RA Mirghani, Ö Ericsson, LL Gustafsson Journal of Chromatography B: Biomedical Sciences and Applications 708 (1-2 …, 1998 | 12 | 1998 |
Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women RA Mirghani, I Elagib, G Elghazali, U Hellgren, LL Gustafsson European journal of clinical pharmacology 66, 1229-1234, 2010 | 11 | 2010 |