| Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 208 | 2019 |
| Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line TL Serafim, PJ Oliveira, VA Sardao, E Perkins, D Parke, J Holy Cancer Chemotherapy and Pharmacology 61, 1007-1018, 2008 | 166 | 2008 |
| Mitochondrially targeted effects of berberine [Natural Yellow 18, 5, 6-dihydro-9, 10-dimethoxybenzo (g)-1, 3-benzodioxolo (5, 6-a) quinolizinium] on K1735-M2 mouse melanoma … GC Pereira, AF Branco, JAC Matos, SL Pereira, D Parke, EL Perkins, ... Journal of pharmacology and experimental therapeutics 323 (2), 636-649, 2007 | 152 | 2007 |
| Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells TL Serafim, FS Carvalho, MPM Marques, R Calheiros, T Silva, J Garrido, ... Chemical research in toxicology 24 (5), 763-774, 2011 | 143 | 2011 |
| Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts AR Coelho, TR Martins, R Couto, C Deus, CV Pereira, RF Simões, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (11 …, 2017 | 71 | 2017 |
| Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells—Nuclear vs. mitochondrial effects TL Serafim, JAC Matos, VA Sardao, GC Pereira, AF Branco, SL Pereira, ... biochemical pharmacology 76 (11), 1459-1475, 2008 | 66 | 2008 |
| Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells CM Deus, TL Serafim, S Magalhães-Novais, A Vilaça, AC Moreira, ... Archives of toxicology 91, 1261-1278, 2017 | 46 | 2017 |
| Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative J Teixeira, R Amorim, K Santos, P Soares, S Datta, GA Cortopassi, ... Toxicology 393, 123-139, 2018 | 41 | 2018 |
| The biochemical response of two commercial bivalve species to exposure to strong salinity changes illustrated by selected biomarkers AMM Gonçalves, DV Barroso, TL Serafim, T Verdelhos, JC Marques, ... Ecological Indicators 77, 59-66, 2017 | 37 | 2017 |
| Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition TC Bernardo, T Cunha-Oliveira, TL Serafim, J Holy, D Krasutsky, ... Bioorganic & medicinal chemistry 21 (23), 7239-7249, 2013 | 37 | 2013 |
| From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia ML Oliveira, P Akkapeddi, I Alcobia, AR Almeida, BA Cardoso, R Fragoso, ... Cellular signalling 38, 10-25, 2017 | 35 | 2017 |
| Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations–relevance for carbaryl toxicity mechanisms AJM Moreno, TL Serafim, PJ Oliveira, VMC Madeira Chemosphere 66 (3), 404-411, 2007 | 34 | 2007 |
| Role of mt DNA‐related mitoepigenetic phenomena in cancer A Ferreira, TL Serafim, VA Sardao, T Cunha‐Oliveira European journal of clinical investigation 45, 44-49, 2015 | 31 | 2015 |
| Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin ET Rodrigues, MÂ Pardal, V Laizé, ML Cancela, PJ Oliveira, TL Serafim Environmental pollution 206, 619-626, 2015 | 27 | 2015 |
| New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death TL Serafim, FS Carvalho, TC Bernardo, GC Pereira, E Perkins, J Holy, ... Bioorganic & Medicinal Chemistry 22 (21), 6270-6287, 2014 | 27 | 2014 |
| Metabolic and phenotypic characterization of human skin fibroblasts after forcing oxidative capacity SP Pereira, CM Deus, TL Serafim, T Cunha-Oliveira, PJ Oliveira Toxicological Sciences 164 (1), 191-204, 2018 | 21 | 2018 |
| Intermediary metabolism: An intricate network at the crossroads of cell fate and function LMR Ferreira, AM Li, TL Serafim, MC Sobral, MC Alpoim, AM Urbano Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (10), 165887, 2020 | 20 | 2020 |
| Analysis of pro-apoptotic protein trafficking to and from mitochondria I Vega-Naredo, T Cunha-Oliveira, TL Serafim, VA Sardao, PJ Oliveira Mitochondrial Regulation: Methods and Protocols, 163-180, 2015 | 20 | 2015 |
| Targeting mitochondrial function for the treatment of breast cancer CM Deus, AR Coelho, TL Serafim, PJ Oliveira Future medicinal chemistry 6 (13), 1499-1513, 2014 | 17 | 2014 |
| Caffeic and ferulic acid derivatives: use in breast cancer TL Serafim, N Milhazes, F Borges, PJ Oliveira Coffee in health and disease prevention, 663-671, 2015 | 11 | 2015 |
