Design of novel antibiotics that bind to the ribosomal acyltransfer site J Haddad, LP Kotra, B Llano-Sotelo, C Kim, EF Azucena, M Liu, ... Journal of the American Chemical Society 124 (13), 3229-3237, 2002 | 200 | 2002 |
Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype C Kim, C Milheiriço, S Gardete, MA Holmes, MTG Holden, H de Lencastre, ... Journal of Biological Chemistry 287 (44), 36854-36863, 2012 | 157 | 2012 |
Genetic Pathway in Acquisition and Loss of Vancomycin Resistance in a Methicillin Resistant Staphylococcus aureus (MRSA) Strain of Clonal Type USA300 S Gardete, C Kim, BM Hartmann, M Mwangi, CM Roux, PM Dunman, ... PLoS pathogens 8 (2), e1002505, 2012 | 149 | 2012 |
The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response C Kim, M Mwangi, M Chung, C Milheirço, H de Lencastre, A Tomasz PLoS One 8 (12), e82814, 2013 | 135 | 2013 |
Whole-Genome Sequencing Reveals a Link Between β-Lactam Resistance and Synthetases of the Alarmone (p)ppGpp in Staphylococcus aureus MM Mwangi, C Kim, M Chung, J Tsai, G Vijayadamodar, M Benitez, ... Microbial Drug Resistance 19 (3), 153-159, 2013 | 98 | 2013 |
Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM β-Lactamase, VL Thomas, D Golemi-Kotra, C Kim, SB Vakulenko, S Mobashery, ... Biochemistry 44 (26), 9330-9338, 2005 | 93 | 2005 |
The importance of a critical protonation state and the fate of the catalytic steps in class A β-lactamases and penicillin-binding proteins D Golemi-Kotra, SO Meroueh, C Kim, SB Vakulenko, A Bulychev, ... Journal of Biological Chemistry 279 (33), 34665-34673, 2004 | 92 | 2004 |
Novel determinants of antibiotic resistance: identification of mutated loci in highly methicillin-resistant subpopulations of methicillin-resistant Staphylococcus aureus J Dordel, C Kim, M Chung, M Pardos de la Gándara, MTJ Holden, ... MBio 5 (2), 10.1128/mbio. 01000-13, 2014 | 87 | 2014 |
Characterization of the Bifunctional Aminoglycoside-Modifying Enzyme ANT(3‘ ‘)-Ii/AAC(6‘)-IId from Serratia marcescens C Kim, D Hesek, J Zajíček, SB Vakulenko, S Mobashery Biochemistry 45 (27), 8368-8377, 2006 | 70 | 2006 |
Mechanistic Characterization of the Bifunctional Aminoglycoside-Modifying Enzyme AAC(3)-Ib/AAC(6‘)-Ib‘ from Pseudomonas aeruginosa C Kim, A Villegas-Estrada, D Hesek, S Mobashery Biochemistry 46 (17), 5270-5282, 2007 | 53 | 2007 |
Comparative Study of the Susceptibilities of Major Epidemic Clones of Methicillin-Resistant Staphylococcus aureus to Oxacillin and to the New Broad-Spectrum … M Chung, A Antignac, C Kim, A Tomasz Antimicrobial agents and chemotherapy 52 (8), 2709-2717, 2008 | 52 | 2008 |
Phosphoryl transfer by aminoglycoside 3′-phosphotransferases and manifestation of antibiotic resistance C Kim, S Mobashery Bioorganic chemistry 33 (3), 149-158, 2005 | 52 | 2005 |
Fluorinated aminoglycosides and their mechanistic implication for aminoglycoside 3 ‘-phosphotransferases from gram-negative bacteria C Kim, J Haddad, SB Vakulenko, SO Meroueh, Y Wu, H Yan, ... Biochemistry 43 (9), 2373-2383, 2004 | 43 | 2004 |
Pardos de la Gandara M, Holden MT, Parkhill J, de Lencastre H, Bentley SD, Tomasz A. 2014 J Dordel, C Kim, M Chung Novel determinants of antibiotic resistance: identification of mutated loci …, 0 | 42 | |
Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics DA Dik, CS Madukoma, S Tomoshige, C Kim, E Lastochkin, WC Boggess, ... ACS chemical biology 14 (2), 296-303, 2019 | 37 | 2019 |
Antibiotic Resistance as a Stress Response: Recovery of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus “Auxiliary” (fem) Mutants … CK Kim, C Milheiriço, H de Lencastre, A Tomasz Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00313-17, 2017 | 33 | 2017 |
Hydrolysis of ATP by aminoglycoside 3′-phosphotransferases: an unexpected cost to bacteria for harboring an antibiotic resistance enzyme C Kim, JY Cha, H Yan, SB Vakulenko, S Mobashery Journal of biological chemistry 281 (11), 6964-6969, 2006 | 29 | 2006 |
Heterogeneous oxacillin-resistant phenotypes and production of PBP2A by oxacillin-susceptible/mecA-positive MRSA strains from Africa M Chung, CK Kim, T Conceiçao, M Aires-De-Sousa, H De Lencastre, ... Journal of Antimicrobial Chemotherapy 71 (10), 2804-2809, 2016 | 28 | 2016 |
Kinetic mechanism of enterococcal aminoglycoside phosphotransferase 2 ‘‘-Ib M Toth, J Zajicek, C Kim, JW Chow, C Smith, S Mobashery, S Vakulenko Biochemistry 46 (18), 5570-5578, 2007 | 26 | 2007 |
Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives C Kim, D Hesek, M Lee, S Mobashery Bioorganic & medicinal chemistry letters 28 (4), 642-645, 2018 | 24 | 2018 |