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Christoph Garbers
Christoph Garbers
Institute of Clinical Biochemistry, Hannover Medical School, Germany
Verified email at mh-hannover.de - Homepage
Title
Cited by
Cited by
Year
Interleukin-6 and its receptors: a highly regulated and dynamic system
J Wolf, S Rose-John, C Garbers
Cytokine 70 (1), 11-20, 2014
6422014
ADAM17: a molecular switch to control inflammation and tissue regeneration
J Scheller, A Chalaris, C Garbers, S Rose-John
Trends in immunology 32 (8), 380-387, 2011
5672011
Interleukin-6: designing specific therapeutics for a complex cytokine
C Garbers, S Heink, T Korn, S Rose-John
Nature Reviews Drug Discovery 17 (6), 395-412, 2018
5232018
The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
C Garbers, S Aparicio-Siegmund, S Rose-John
Current Opinion in Immunology 34, 75-82, 2015
4272015
Plasticity and cross-talk of Interleukin 6-type cytokines
C Garbers, HM Hermanns, F Schaper, G Müller-Newen, J Grötzinger, ...
Cytokine & Growth Factor Reviews, 2012
3962012
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH 17 cells
S Heink, N Yogev, C Garbers, M Herwerth, L Aly, C Gasperi, V Husterer, ...
Nature immunology 18 (1), 74-85, 2017
3742017
The soluble Interleukin 6 receptor: generation and role in inflammation and cancer
A Chalaris, C Garbers, B Rabe, S Rose-John, J Scheller
European journal of cell biology 90 (6), 484-494, 2011
3532011
Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities
J Scheller, C Garbers, S Rose-John
Seminars in immunology 26 (1), 2-12, 2014
3462014
Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
C Garbers, N Jänner, A Chalaris, ML Moss, DM Floss, D Meyer, ...
Journal of Biological Chemistry 286 (17), 14804, 2011
2322011
Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor
C Garbers, W Thaiss, GW Jones, GH Waetzig, I Lorenzen, F Guilhot, ...
Journal of Biological Chemistry 286 (50), 42959-42970, 2011
1902011
Interleukin-6 and interleukin-11: same same but different
C Garbers, J Scheller
Biological chemistry 394 (9), 1145-1161, 2013
1482013
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to …
N Schumacher, D Meyer, A Mauermann, J von der Heyde, J Wolf, ...
Journal of Biological Chemistry 290 (43), 26059-26071, 2015
1472015
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases
C Garbers, N Monhasery, S Aparicio-Siegmund, J Lokau, P Baran, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014
1452014
Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease
S Schreiber, K Aden, JP Bernardes, C Conrad, F Tran, H Höper, V Volk, ...
Gastroenterology 160 (7), 2354-2366. e11, 2021
1362021
An interleukin-6 receptor-dependent molecular switch mediates signal transduction of the IL-27 cytokine subunit p28 (IL-30) via a gp130 receptor homodimer
C Garbers, B Spudy, S Aparicio-Siegmund, GH Waetzig, J Sommer, ...
Journal of Biological Chemistry, 2012
1312012
A Disintegrin and Metalloprotease (ADAM) 10 and ADAM17 Are Major Sheddases of T Cell Immunoglobulin and Mucin Domain 3 (Tim-3)
K Möller-Hackbarth, C Dewitz, O Schweigert, A Trad, C Garbers, ...
Journal of Biological Chemistry 288 (48), 34529-34544, 2013
1272013
IL-6< i> trans</i>-Signaling-Dependent Rapid Development of Cytotoxic CD8< sup>+</sup> T Cell Function
JP Böttcher, O Schanz, C Garbers, A Zaremba, S Hegenbarth, C Kurts, ...
Cell Reports, 2014
1232014
Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation
S Riethmueller, P Somasundaram, JC Ehlers, CW Hung, CM Flynn, ...
PLoS biology 15 (1), e2000080, 2017
1212017
Control of ADAM17 activity by regulation of its cellular localisation
I Lorenzen, J Lokau, Y Korpys, M Oldefest, CM Flynn, U Künzel, ...
Scientific Reports 6, 35067, 2016
1212016
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.
CM Wunderlich, PJ Ackermann, AL Ostermann, P Adams-Quack, MC Vogt, ...
Nature communications 9 (1), 1646-1646, 2018
1162018
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