Excess S‐adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis M Martínez‐Uña, M Varela‐Rey, A Cano, L Fernández‐Ares, N Beraza, ... Hepatology 58 (4), 1296-1305, 2013 | 127 | 2013 |
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling JL García‐Rodríguez, L Barbier‐Torres, S Fernández‐Álvarez, ... Hepatology 59 (5), 1972-1983, 2014 | 123 | 2014 |
Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low‐density lipoprotein assembly in mice A Cano, X Buqué, M Martínez‐Uña, I Aurrekoetxea, A Menor, ... Hepatology 54 (6), 1975-1986, 2011 | 113 | 2011 |
Human antigen R contributes to hepatic stellate cell activation and liver fibrosis A Woodhoo, M Iruarrizaga‐Lejarreta, N Beraza, JL García‐Rodríguez, ... Hepatology 56 (5), 1870-1882, 2012 | 102 | 2012 |
Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer L Barbier-Torres, TC Delgado, JL García-Rodríguez, I Zubiete-Franco, ... Oncotarget 6 (4), 2509, 2015 | 96 | 2015 |
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis I Zubiete-Franco, JL García-Rodríguez, M Martínez-Uña, ... Journal of hepatology 64 (2), 409-418, 2016 | 76 | 2016 |
Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1 N Martínez–López, JL García–Rodríguez, M Varela–Rey, V Gutiérrez, ... Gastroenterology 143 (3), 787-798. e13, 2012 | 70 | 2012 |
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer I Zubiete-Franco, JL García-Rodríguez, F Lopitz-Otsoa, M Serrano-Macia, ... EBioMedicine 40, 406-421, 2019 | 57 | 2019 |
A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma C Huidobro, EG Toraño, AF Fernández, RG Urdinguio, RM Rodríguez, ... Journal of molecular medicine 91, 939-950, 2013 | 37 | 2013 |
E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment F González-Romero, D Mestre, I Aurrekoetxea, CJ O'Rourke, ... Cancer research 81 (11), 2874-2887, 2021 | 32 | 2021 |
Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease M Vazquez‐Chantada, A Gonzalez‐Lahera, I Martinez‐Arranz, ... Hepatology 57 (2), 505-514, 2013 | 31 | 2013 |
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis D Sáenz de Urturi, X Buqué, B Porteiro, C Folgueira, A Mora, TC Delgado, ... Nature communications 13 (1), 1096, 2022 | 26 | 2022 |
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver [S] M Nuñez-Garcia, B Gomez-Santos, X Buqué, JL García-Rodriguez, ... Journal of Lipid Research 58 (9), 1903-1915, 2017 | 26 | 2017 |
Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications H Khanbabaei, S Ebrahimi, JL García-Rodríguez, Z Ghasemi, ... Journal of Experimental & Clinical Cancer Research 41 (1), 278, 2022 | 23 | 2022 |
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics YD Benoit, RR Mitchell, W Wang, L Orlando, AL Boyd, B Tanasijevic, ... Cell chemical biology 28 (10), 1394-1406. e10, 2021 | 15 | 2021 |
circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in Small Cell Lung Cancer D Tolomeo, D Traversa, S Venuto, KK Ebbesen, JLG Rodríguez, ... Genes, chromosomes & cancer, 2022 | 12 | 2022 |
Phosphorylation state of the histone variant H2A. X controls human stem and progenitor cell fate decisions L Orlando, B Tanasijevic, M Nakanishi, JC Reid, JL García-Rodríguez, ... Cell Reports 34 (10), 2021 | 12 | 2021 |
Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients L Aslostovar, AL Boyd, YD Benoit, J Di Lu, JLG Rodriguez, M Nakanishi, ... Cell Reports Medicine 2 (2), 2021 | 9 | 2021 |
Chemical genomics reveals targetable programs of human cancers rooted in pluripotency L Orlando, YD Benoit, JC Reid, M Nakanishi, AL Boyd, ... Cell chemical biology 30 (7), 780-794. e8, 2023 | 4 | 2023 |
Spatial profiling of circular RNAs in cancer reveals high expression in muscle and stromal cells JL García-Rodríguez, U Korsgaard, U Ahmadov, MT Jarlstad Olesen, ... Cancer research 83 (20), 3340-3353, 2023 | 2 | 2023 |