| Succination inactivates gasdermin D and blocks pyroptosis F Humphries, L Shmuel-Galia, N Ketelut-Carneiro, S Li, B Wang, ... Science 369 (6511), 1633-1637, 2020 | 393 | 2020 |
| RIP kinases: key decision makers in cell death and innate immunity F Humphries, S Yang, B Wang, PN Moynagh Cell Death & Differentiation 22 (2), 225-236, 2015 | 271 | 2015 |
| The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome F Humphries, R Bergin, R Jackson, N Delagic, B Wang, S Yang, ... Nature communications 9 (1), 1560, 2018 | 145 | 2018 |
| Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ... Nature immunology 14 (9), 927-936, 2013 | 111 | 2013 |
| A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection F Humphries, L Shmuel-Galia, Z Jiang, R Wilson, P Landis, SL Ng, ... Science Immunology 6 (59), eabi9002, 2021 | 106 | 2021 |
| STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, ... Nature communications 11 (1), 3816, 2020 | 95 | 2020 |
| Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses A Hanuszkiewicz, P Pittock, F Humphries, H Moll, AR Rosales, A Molinaro, ... Journal of Biological Chemistry 289 (27), 19231-19244, 2014 | 76 | 2014 |
| Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells L Shmuel-Galia, F Humphries, X Lei, S Ceglia, R Wilson, Z Jiang, ... Immunity 54 (6), 1137-1153. e8, 2021 | 56 | 2021 |
| The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance S Yang, B Wang, F Humphries, AE Hogan, D O’Shea, PN Moynagh Immunity 41 (6), 973-987, 2014 | 51 | 2014 |
| Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity F Humphries, PN Moynagh Immunological Reviews 266 (1), 93-108, 2015 | 28 | 2015 |
| Platelets and SARS-CoV-2 during COVID-19: immunity, thrombosis, and beyond A Sciaudone, H Corkrey, F Humphries, M Koupenova Circulation Research 132 (10), 1272-1289, 2023 | 16 | 2023 |
| Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection VN Hariharan, M Shin, CW Chang, D O’Reilly, A Biscans, K Yamada, ... Proceedings of the National Academy of Sciences 120 (11), e2219523120, 2023 | 15 | 2023 |
| Targeting STING oligomerization with small-molecule inhibitors F Humphries, L Shmuel-Galia, Z Jiang, JY Zhou, L Barasa, S Mondal, ... Proceedings of the National Academy of Sciences 120 (33), e2305420120, 2023 | 12 | 2023 |
| Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade Y Jiang, Y Yang, Y Hu, R Yang, J Huang, Y Liu, Y Wu, S Li, C Ma, ... Cell Reports 41 (4), 2022 | 11 | 2022 |
| hnRNPA2B1: fueling antiviral immunity from the nucleus F Humphries, KA Fitzgerald Molecular cell 76 (1), 8-10, 2019 | 11 | 2019 |
| UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis H Kim, Y Subbannayya, F Humphries, A Skejsol, SM Pinto, ... PLoS One 16 (10), e0258989, 2021 | 10 | 2021 |
| ECSIT is a critical limiting factor for cardiac function L Xu, F Humphries, N Delagic, B Wang, A Holland, KS Edgar, ... JCI insight 6 (12), 2021 | 9 | 2021 |
| Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants Q Li, F Humphries, RC Girardin, A Wallace, M Ejemel, A Amcheslavsky, ... Frontiers in immunology 13, 995412, 2022 | 7 | 2022 |
| Secretory Leucoprotease Inhibitor (SLPI) Promotes Survival during Acute Pseudomonas aeruginosa Infection by Suppression of Inflammation Rather Than … M Osbourn, AM Rodgers, AV Dubois, DM Small, F Humphries, N Delagic, ... Biomolecules 12 (12), 1728, 2022 | 6 | 2022 |
| Development of LB244, an irreversible STING antagonist L Barasa, S Chaudhuri, JY Zhou, Z Jiang, S Choudhary, RM Green, ... Journal of the American Chemical Society 145 (37), 20273-20288, 2023 | 5 | 2023 |
