mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop K Kume, MJ Zylka, S Sriram, LP Shearman, DR Weaver, X Jin, ... Cell 98 (2), 193-205, 1999 | 2008 | 1999 |
Interacting molecular loops in the mammalian circadian clock LP Shearman, S Sriram, DR Weaver, ES Maywood, I Chaves, B Zheng, ... Science 288 (5468), 1013-1019, 2000 | 1741 | 2000 |
Role of cytosolic phospholipase A2 in allergic response and parturition N Uozumi, K Kume, T Nagase, N Nakatani, S Ishii, F Tashiro, Y Komagata, ... Nature 390 (6660), 618-622, 1997 | 877 | 1997 |
Dopamine is a regulator of arousal in the fruit fly K Kume, S Kume, SK Park, J Hirsh, FR Jackson Journal of Neuroscience 25 (32), 7377-7384, 2005 | 619 | 2005 |
Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells N Shiraki, Y Shiraki, T Tsuyama, F Obata, M Miura, G Nagae, H Aburatani, ... Cell metabolism 19 (5), 780-794, 2014 | 546 | 2014 |
High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe K Okazaki, N Okazaki, K Kume, S Jinno, K Tanaka, H Okayama Nucleic acids research 18 (22), 6485-6489, 1990 | 514 | 1990 |
Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR K Ito, H Suzuki, T Hirohashi, K Kume, T Shimizu, Y Sugiyama American Journal of Physiology-Gastrointestinal and Liver Physiology 272 (1 …, 1997 | 418 | 1997 |
Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2 T Nagase, N Uozumi, S Ishii, K Kume, T Izumi, Y Ouchi, T Shimizu Nature immunology 1 (1), 42-46, 2000 | 370 | 2000 |
Hepatic expression of multidrug resistance-associated protein-like proteins maintained in Eisai hyperbilirubinemic rats T Hirohashi, H Suzuki, K Ito, K Ogawa, K Kume, T Shimizu, Y Sugiyama Molecular Pharmacology 53 (6), 1068-1075, 1998 | 333 | 1998 |
Identification of a dopamine pathway that regulates sleep and arousal in Drosophila T Ueno, J Tomita, H Tanimoto, K Endo, K Ito, S Kume, K Kume Nature neuroscience 15 (11), 1516-1523, 2012 | 332 | 2012 |
Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor S Ishii, T Kuwaki, T Nagase, K Maki, F Tashiro, S Sunaga, WH Cao, ... The Journal of experimental medicine 187 (11), 1779-1788, 1998 | 316 | 1998 |
Forward-genetics analysis of sleep in randomly mutagenized mice H Funato, C Miyoshi, T Fujiyama, T Kanda, M Sato, Z Wang, J Ma, ... Nature 539 (7629), 378-383, 2016 | 296 | 2016 |
Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain J Morales, PR Hiesinger, AJ Schroeder, K Kume, P Verstreken, ... Neuron 34 (6), 961-972, 2002 | 288 | 2002 |
Behavioral consequences of dopamine deficiency in the Drosophila central nervous system T Riemensperger, G Isabel, H Coulom, K Neuser, L Seugnet, K Kume, ... Proceedings of the National Academy of Sciences 108 (2), 834-839, 2011 | 286 | 2011 |
Gender dimorphism in the role of cycle (BMAL1) in rest, rest regulation, and longevity in Drosophila melanogaster JC Hendricks, S Lu, K Kume, JCP Yin, Z Yang, A Sehgal Journal of biological rhythms 18 (1), 12-25, 2003 | 212 | 2003 |
Critical duration of intracellular Ca2+ response required for continuous translocation and activation of cytosolic phospholipase A2 T Hirabayashi, K Kume, K Hirose, T Yokomizo, M Iino, H Itoh, T Shimizu Journal of Biological Chemistry 274 (8), 5163-5169, 1999 | 195 | 1999 |
The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster H Sano, A Nakamura, MJ Texada, JW Truman, H Ishimoto, A Kamikouchi, ... PLoS genetics 11 (5), e1005209, 2015 | 189 | 2015 |
Cytosolic Phospholipase A2α–deficient Mice Are Resistant to Collagen-induced Arthritis M Hegen, L Sun, N Uozumi, K Kume, ME Goad, CL Nickerson-Nutter, ... The Journal of experimental medicine 197 (10), 1297-1302, 2003 | 188 | 2003 |
Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet‐activating factor receptor S Ishii, T Nagase, F Tashiro, K Ikuta, S Sato, I Waga, K Kume, J Miyazaki, ... The EMBO Journal, 1997 | 176 | 1997 |
Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice T Nagase, S Ishii, K Kume, N Uozumi, T Izumi, Y Ouchi, T Shimizu The Journal of clinical investigation 104 (8), 1071-1076, 1999 | 161 | 1999 |