| ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER R Ushioda, J Hoseki, K Araki, G Jansen, DY Thomas, K Nagata Science 321 (5888), 569-572, 2008 | 438 | 2008 |
| Mechanism and components of endoplasmic reticulum-associated degradation J Hoseki, R Ushioda, K Nagata Journal of biochemistry 147 (1), 19-25, 2010 | 239 | 2010 |
| Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition S Maharjan, M Oku, M Tsuda, J Hoseki, Y Sakai Scientific reports 4 (1), 5896, 2014 | 210 | 2014 |
| Directed evolution of thermostable kanamycin-resistance gene: a convenient selection marker for Thermus thermophilus J Hoseki, T Yano, Y Koyama, S Kuramitsu, H Kagamiyama The journal of biochemistry 126 (5), 951-956, 1999 | 206 | 1999 |
| ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element N Mizobuchi, J Hoseki, H Kubota, S Toyokuni, J Nozaki, M Naitoh, ... Cell structure and function 32 (1), 41-50, 2007 | 203 | 2007 |
| Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5 M Hagiwara, K Maegawa, M Suzuki, R Ushioda, K Araki, Y Matsumoto, ... Molecular cell 41 (4), 432-444, 2011 | 161 | 2011 |
| Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state D Morito, K Nishikawa, J Hoseki, A Kitamura, Y Kotani, K Kiso, M Kinjo, ... Scientific reports 4 (1), 4442, 2014 | 110 | 2014 |
| Glycosylation-independent ERAD pathway serves as a backup system under ER stress R Ushioda, J Hoseki, K Nagata Molecular biology of the cell 24 (20), 3155-3163, 2013 | 107 | 2013 |
| Crystal structure of a family 4 uracil-DNA glycosylase from Thermus thermophilus HB8 J Hoseki, A Okamoto, R Masui, T Shibata, Y Inoue, S Yokoyama, ... Journal of molecular biology 333 (3), 515-526, 2003 | 79 | 2003 |
| Structural Insights into the Enzymatic Mechanism of Serine Palmitoyltransferase from Sphingobacterium multivorum H Ikushiro, MM Islam, A Okamoto, J Hoseki, T Murakawa, S Fujii, ... The journal of biochemistry 146 (4), 549-562, 2009 | 66 | 2009 |
| Crystal structure of family 5 uracil-DNA glycosylase bound to DNA H Kosaka, J Hoseki, N Nakagawa, S Kuramitsu, R Masui Journal of molecular biology 373 (4), 839-850, 2007 | 54 | 2007 |
| Novel thioredoxin-related transmembrane protein TMX4 has reductase activity Y Sugiura, K Araki, S Iemura, T Natsume, J Hoseki, K Nagata Journal of biological chemistry 285 (10), 7135-7142, 2010 | 52 | 2010 |
| Proinsulin lacking the A7-B7 disulfide bond, Ins2Akita, tends to aggregate due to the exposed hydrophobic surface T Yoshinaga, K Nakatome, J Nozaki, M Naitoh, J Hoseki, H Kubota, ... Walter de Gruyter 386 (11), 1077-1085, 2005 | 39 | 2005 |
| Synthesized Aβ42 caused intracellular oxidative damage, leading to cell death, via lysosome rupture Y Oku, K Murakami, K Irie, J Hoseki, Y Sakai Cell structure and function 42 (1), 71-79, 2017 | 37 | 2017 |
| Solution structure and dynamics of mouse ARMET J Hoseki, H Sasakawa, Y Yamaguchi, M Maeda, H Kubota, K Kato, ... FEBS letters 584 (8), 1536-1542, 2010 | 37 | 2010 |
| Development of a stable ERroGFP variant suitable for monitoring redox dynamics in the ER J Hoseki, A Oishi, T Fujimura, Y Sakai Bioscience reports 36 (2), e00316, 2016 | 26 | 2016 |
| Increased rigidity of domain structures enhances the stability of a mutant enzyme created by directed evolution J Hoseki, A Okamoto, N Takada, A Suenaga, N Futatsugi, A Konagaya, ... Biochemistry 42 (49), 14469-14475, 2003 | 24 | 2003 |
| A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae M Oku, J Hoseki, Y Ichiki, Y Sakai FEBS letters 587 (6), 793-798, 2013 | 20 | 2013 |
| NMR and mutational identification of the collagen-binding site of the chaperone Hsp47 M Yagi-Utsumi, S Yoshikawa, Y Yamaguchi, Y Nishi, E Kurimoto, Y Ishida, ... Public Library of Science 7 (9), e45930, 2012 | 19 | 2012 |
| Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state S Maharjan, Y Sakai, J Hoseki Bioscience, biotechnology, and biochemistry 80 (4), 726-734, 2016 | 9 | 2016 |
