| Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease SL Bernstein, NF Dupuis, ND Lazo, T Wyttenbach, MM Condron, G Bitan, ... Nature chemistry 1 (4), 326-331, 2009 | 856 | 2009 |
| FROM FOLDING THEORIES TO FOLDING PROTEINS: A Review and Assessment of Simulation Studies of Protein Folding and Unfolding JE Shea, CL Brooks III Annual review of physical chemistry 52 (1), 499-535, 2001 | 574 | 2001 |
| Amyloid β-Protein: Monomer Structure and Early Aggregation States of Aβ42 and Its Pro19 Alloform SL Bernstein, T Wyttenbach, A Baumketner, JE Shea, G Bitan, DB Teplow, ... Journal of the American Chemical Society 127 (7), 2075-2084, 2005 | 387 | 2005 |
| Amyloid β‐protein monomer structure: A computational and experimental study A Baumketner, SL Bernstein, T Wyttenbach, G Bitan, DB Teplow, ... Protein Science 15 (3), 420-428, 2006 | 276 | 2006 |
| Elucidating amyloid β-protein folding and assembly: a multidisciplinary approach DB Teplow, ND Lazo, G Bitan, S Bernstein, T Wyttenbach, MT Bowers, ... Accounts of chemical research 39 (9), 635-645, 2006 | 251 | 2006 |
| Exploring the origins of topological frustration: design of a minimally frustrated model of fragment B of protein A JE Shea, JN Onuchic, CL Brooks Proceedings of the National Academy of Sciences 96 (22), 12512-12517, 1999 | 240 | 1999 |
| Human islet amyloid polypeptide monomers form ordered β-hairpins: a possible direct amyloidogenic precursor NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 131 (51), 18283-18292, 2009 | 206 | 2009 |
| The amyloid formation mechanism in human IAPP: dimers have β-strand monomer− monomer interfaces NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 133 (19), 7240-7243, 2011 | 201 | 2011 |
| Coarse-grained models for protein aggregation C Wu, JE Shea Current opinion in structural biology 21 (2), 209-220, 2011 | 188 | 2011 |
| Role of water in mediating the assembly of Alzheimer amyloid-β Aβ16− 22 protofilaments MG Krone, L Hua, P Soto, R Zhou, BJ Berne, JE Shea Journal of the American Chemical Society 130 (33), 11066-11072, 2008 | 187 | 2008 |
| Effects of solvent on the structure of the Alzheimer amyloid-β (25–35) peptide G Wei, JE Shea Biophysical journal 91 (5), 1638-1647, 2006 | 170 | 2006 |
| Probing the folding free energy landscape of the src-SH3 protein domain JE Shea, JN Onuchic, CL Brooks Proceedings of the National Academy of Sciences 99 (25), 16064-16068, 2002 | 167 | 2002 |
| Structure of the 21–30 fragment of amyloid β‐protein A Baumketner, SL Bernstein, T Wyttenbach, ND Lazo, DB Teplow, ... Protein Science 15 (6), 1239-1247, 2006 | 159 | 2006 |
| The structure of the Alzheimer amyloid β 10-35 peptide probed through replica-exchange molecular dynamics simulations in explicit solvent A Baumketner, JE Shea Journal of molecular biology 366 (1), 275-285, 2007 | 146 | 2007 |
| The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer’s disease Aβ16–22 peptide probed by molecular dynamics simulations C Wu, Z Wang, H Lei, Y Duan, MT Bowers, JE Shea Journal of molecular biology 384 (3), 718-729, 2008 | 141 | 2008 |
| Computational studies of protein aggregation: methods and applications A Morriss-Andrews, JE Shea Annual review of physical chemistry 66, 643-666, 2015 | 134 | 2015 |
| Regulation and aggregation of intrinsically disordered peptides ZA Levine, L Larini, NE LaPointe, SC Feinstein, JE Shea Proceedings of the National Academy of Sciences 112 (9), 2758-2763, 2015 | 132 | 2015 |
| Binding of Congo red to amyloid protofibrils of the Alzheimer Aβ9–40 peptide probed by molecular dynamics simulations C Wu, J Scott, JE Shea Biophysical journal 103 (3), 550-557, 2012 | 131 | 2012 |
| Effects of confinement in chaperonin assisted protein folding: rate enhancement by decreasing the roughness of the folding energy landscape A Baumketner, A Jewett, JE Shea Journal of molecular biology 332 (3), 701-713, 2003 | 123 | 2003 |
| Accelerated folding in the weak hydrophobic environment of a chaperonin cavity: creation of an alternate fast folding pathway AI Jewett, A Baumketner, JE Shea Proceedings of the National Academy of Sciences 101 (36), 13192-13197, 2004 | 121 | 2004 |
