Julien Muffat
Julien Muffat
The Hospital for Sick Children
Verified email at
Cited by
Cited by
A three-dimensional human neural cell culture model of Alzheimer’s disease
SH Choi, YH Kim, M Hebisch, C Sliwinski, S Lee, C D’Avanzo, H Chen, ...
Nature 515 (7526), 274-278, 2014
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
J Hanna, AW Cheng, K Saha, J Kim, CJ Lengner, F Soldner, JP Cassady, ...
Proceedings of the National Academy of Sciences 107 (20), 9222-9227, 2010
Efficient derivation of microglia-like cells from human pluripotent stem cells
J Muffat, Y Li, B Yuan, M Mitalipova, A Omer, S Corcoran, G Bakiasi, ...
Nature medicine 22 (11), 1358-1367, 2016
Cytosolic β-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease
LE Goldstein, JA Muffat, RA Cherny, RD Moir, MH Ericsson, X Huang, ...
The Lancet 361 (9365), 1258-1265, 2003
Identification and rescue of α-synuclein toxicity in Parkinson patient–derived neurons
CY Chung, V Khurana, PK Auluck, DF Tardiff, JR Mazzulli, F Soldner, ...
Science 342 (6161), 983-987, 2013
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ...
Cell 141 (5), 872-883, 2010
Induction of expansion and folding in human cerebral organoids
Y Li, J Muffat, A Omer, I Bosch, MA Lancaster, M Sur, L Gehrke, ...
Cell stem cell 20 (3), 385-396. e3, 2017
Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons
Y Li, H Wang, J Muffat, AW Cheng, DA Orlando, J Lovén, S Kwok, ...
Cell stem cell 13 (4), 446-458, 2013
3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote α-crystallin cross-linking by metal ion reduction
LE Goldstein, MC Leopold, X Huang, CS Atwood, AJ Saunders, ...
Biochemistry 39 (24), 7266-7275, 2000
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions
K Saha, Y Mei, CM Reisterer, NK Pyzocha, J Yang, J Muffat, MC Davies, ...
Proceedings of the National Academy of Sciences 108 (46), 18714-18719, 2011
ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state
Y Chudnovsky, D Kim, S Zheng, WA Whyte, M Bansal, MA Bray, S Gopal, ...
Cell reports 6 (2), 313-324, 2014
Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz
J Hull-Thompson, J Muffat, D Sanchez, DW Walker, S Benzer, ...
PLoS genetics 5 (4), e1000460, 2009
Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan
DW Walker, J Muffat, C Rundel, S Benzer
Current Biology 16 (7), 674-679, 2006
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila
J Muffat, DW Walker, S Benzer
Proceedings of the National Academy of Sciences 105 (19), 7088-7093, 2008
Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections
J Muffat, Y Li, A Omer, A Durbin, I Bosch, G Bakiasi, E Richards, A Meyer, ...
Proceedings of the National Academy of Sciences 115 (27), 7117-7122, 2018
Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant
DW Walker, P Hájek, J Muffat, D Knoepfle, S Cornelison, G Attardi, ...
Proceedings of the National Academy of Sciences 103 (44), 16382-16387, 2006
Genome-wide CRISPR screen for Zika virus resistance in human neural cells
Y Li, J Muffat, A Omer Javed, HR Keys, T Lungjangwa, I Bosch, M Khan, ...
Proceedings of the National Academy of Sciences 116 (19), 9527-9532, 2019
Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases
M Trapecar, E Wogram, D Svoboda, C Communal, A Omer, ...
Science Advances 7 (5), eabd1707, 2021
Apolipoprotein D: an overview of its role in aging and age-related diseases
J Muffat, DW Walker
Cell Cycle 9 (2), 269-273, 2010
The system can't perform the operation now. Try again later.
Articles 1–20