フォロー
Ulf H. Beier
Ulf H. Beier
Janssen R&D
確認したメール アドレス: its.jnj.com
タイトル
引用先
引用先
Foxp3 reprograms T cell metabolism to function in low-glucose, high-lactate environments
A Angelin, L Gil-de-Gómez, S Dahiya, J Jiao, L Guo, MH Levine, Z Wang, ...
Cell metabolism 25 (6), 1282-1293. e7, 2017
9002017
Helios expression is a marker of T cell activation and proliferation
T Akimova, UH Beier, L Wang, MH Levine, WW Hancock
PloS one 6 (8), e24226, 2011
4842011
Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3+ T-regulatory cells
EF de Zoeten, L Wang, K Butler, UH Beier, T Akimova, H Sai, JE Bradner, ...
Molecular and cellular biology, 2011
2812011
Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival
UH Beier, A Angelin, T Akimova, L Wang, Y Liu, H Xiao, MA Koike, ...
The FASEB journal 29 (6), 2315, 2015
2452015
Inhibition of p300 impairs Foxp3+ T regulatory cell function and promotes antitumor immunity
Y Liu, L Wang, J Predina, R Han, UH Beier, LCS Wang, V Kapoor, ...
Nature medicine 19 (9), 1173-1177, 2013
2262013
Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft Survival
UH Beier, L Wang, TR Bhatti, Y Liu, R Han, G Ge, WW Hancock
Molecular and cellular biology 31 (5), 1022-1029, 2011
2202011
Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms
UH Beier, L Wang, R Han, T Akimova, Y Liu, WW Hancock
Science signaling 5 (229), ra45-ra45, 2012
2132012
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer
S Singhal, J Stadanlick, MJ Annunziata, AS Rao, PS Bhojnagarwala, ...
Science translational medicine 11 (479), eaat1500, 2019
2022019
Lactate limits T cell proliferation via the NAD (H) redox state
WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ...
Cell reports 33 (11), 2020
1652020
Histone/protein deacetylases and T-cell immune responses
T Akimova, UH Beier, Y Liu, L Wang, WW Hancock
Blood, The Journal of the American Society of Hematology 119 (11), 2443-2451, 2012
1512012
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ...
Nature chemical biology 16 (7), 731-739, 2020
1152020
Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells
UH Beier, T Akimova, Y Liu, L Wang, WW Hancock
Current opinion in immunology 23 (5), 670-678, 2011
1142011
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function
L Wang, Y Liu, R Han, UH Beier, RM Thomas, AD Wells, WW Hancock
Molecular and cellular biology 33 (20), 4106-4115, 2013
1102013
Ubiquitin-specific protease-7 inhibition impairs Tip60-dependent Foxp3+ T-regulatory cell function and promotes antitumor immunity
L Wang, S Kumar, S Dahiya, F Wang, J Wu, K Newick, R Han, A Samanta, ...
EBioMedicine 13, 99-112, 2016
1092016
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3
L Wang, Y Liu, R Han, UH Beier, TR Bhatti, T Akimova, MI Greene, ...
The Journal of clinical investigation 125 (3), 1111-1123, 2015
1042015
Metalloproteinases and their inhibitors: influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas
T Görögh, UH Beier, J Bäumken, JE Meyer, M Hoffmann, S Gottschlich, ...
Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2006
982006
Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-Regulatory Cell Development and Function
Y Liu, L Wang, R Han, UH Beier, T Akimova, T Bhatti, H Xiao, PA Cole, ...
Molecular and cellular biology 34 (21), 3993-4007, 2014
902014
HDAC inhibitor therapy in autoimmunity and transplantation
WW Hancock, T Akimova, UH Beier, Y Liu, L Wang
Annals of the rheumatic diseases 71 (Suppl 2), i46-i54, 2012
892012
Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity
L Wang, Y Liu, UH Beier, R Han, TR Bhatti, T Akimova, WW Hancock
Blood, The Journal of the American Society of Hematology 121 (18), 3631-3639, 2013
872013
Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
J Huang, L Wang, S Dahiya, UH Beier, R Han, A Samanta, J Bergman, ...
Scientific reports 7 (1), 8626, 2017
762017
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