フォロー
Saurabh k Bhardwaj
Saurabh k Bhardwaj
Janssen Inc., Pfizer Inc. , Children's Hospital of Philadelphia
確認したメール アドレス: siu.edu
タイトル
引用先
引用先
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells
JD Grevet, X Lan, N Hamagami, CR Edwards, L Sankaranarayanan, X Ji, ...
Science 361 (6399), 285-290, 2018
1422018
INO80 exchanges H2A. Z for H2A by translocating on DNA proximal to histone dimers
S Brahma, MI Udugama, J Kim, A Hada, SK Bhardwaj, SG Hailu, TH Lee, ...
Nature communications 8 (1), 15616, 2017
1362017
Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains
SK Hota, SK Bhardwaj, S Deindl, Y Lin, X Zhuang, B Bartholomew
Nature structural & molecular biology 20 (2), 222-229, 2013
822013
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells
X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ...
Blood Advances 3 (10), 1586-1597, 2019
312019
Histone octamer structure is altered early in ISW2 ATP-dependent nucleosome remodeling
A Hada, SK Hota, J Luo, Y Lin, S Kale, AK Shaytan, SK Bhardwaj, ...
Cell reports 28 (1), 282-294. e6, 2019
252019
Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation
SK Bhardwaj, SG Hailu, L Olufemi, S Brahma, S Kundu, SK Hota, ...
Nature communications 11 (1), 5913, 2020
172020
Robust erythroid differentiation system for rhesus hematopoietic progenitor cells allowing preclinical screening of genetic treatment strategies for the hemoglobinopathies
S Demirci, SK Bhardwaj, N Uchida, JJ Haro-Mora, B Ryu, GA Blobel, ...
Cytotherapy 20 (10), 1278-1287, 2018
62018
INO80 exchanges H2A. Z for H2A by translocating on DNA proximal to histone dimers. Nat. Commun. 8, 15616
S Brahma, MI Udugama, J Kim, A Hada, SK Bhardwaj, SG Hailu, TH Lee, ...
52017
Forced enhancer-promoter rewiring to alter gene expression in animal models
SA Peslak, S Demirci, V Chandra, B Ryu, SK Bhardwaj, J Jiang, ...
Molecular Therapy-Nucleic Acids 31, 452-465, 2023
22023
Domain-focused CRISPR-Cas9 screen identifies the E3 ubiquitin ligase substrate adaptor protein SPOP as a novel repressor of fetal hemoglobin
X Lan, E Khandros, JD Grevet, SA Peslak, S Bhardwaj, CA Keller, ...
Blood 132 (Supplement 1), 414-414, 2018
12018
Fetal hemoglobin induction with forced chromatin looping in gene-modified erythroid cells differentiated from rhesus hematopoietic progenitor cells
S Demirci, S Bhardwaj, N Uchida, JJH Mora, BY Ryu, GA Blobel, ...
Blood 130, 4617, 2017
12017
Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells
JD Grevet, N Hamagami, X Lan, L Sankaranarayanan, S Bhardwaj, ...
Blood 130, 536, 2017
2017
The mechanisms of ISW1a, ISW1b and ISW2 chromatin remodelers
SK Bhardwaj
Southern Illinois University at Carbondale, 2015
2015
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論文 1–13