TUT 7 controls the fate of precursor micro RNA s by using three different uridylation mechanisms B Kim*, M Ha*, L Loeff*, H Chang, DK Simanshu, S Li, M Fareh, DJ Patel, ... The EMBO journal 34 (13), 1801-1815, 2015 | 125 | 2015 |
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex TR Blosser*, L Loeff*, ER Westra, M Vlot, T Künne, M Sobota, C Dekker, ... Molecular cell 58 (1), 60-70, 2015 | 119 | 2015 |
Repetitive DNA Reeling by the Cascade-Cas3 Complex in Nucleotide Unwinding Steps L Loeff, SJJ Brouns, C Joo Molecular Cell 70 (3), 385–394, 2018 | 68 | 2018 |
Selective loading and processing of prespacers for precise CRISPR adaptation S Kim*, L Loeff*, S Colombo, S Jergic, SJJ Brouns, C Joo Nature 579 (7797), 141-145, 2020 | 54 | 2020 |
R-loop formation and conformational activation mechanisms of Cas9 M Pacesa, L Loeff, I Querques, LM Muckenfuss, M Sawicka, M Jinek Nature 609 (7925), 191-196, 2022 | 50* | 2022 |
AutoStepfinder: A fast and automated step detection method for single-molecule analysis L Loeff*, JWJ Kerssemakers*, C Joo, C Dekker, E contribution Patterns 2 (5), 100256, 2021 | 32 | 2021 |
Proteome Adaptation of Saccharomyces cerevisiae to Severe Calorie Restriction in Retentostat Cultures NA Binai, MMM Bisschops, B van Breukelen, S Mohammed, L Loeff, ... Journal of proteome research 13 (8), 3542-3553, 2014 | 20 | 2014 |
Single-molecule pull-down for investigating protein–nucleic acid interactions M Fareh, L Loeff, M Szczepaniak, AC Haagsma, KH Yeom, C Joo Methods 105, 99-108, 2016 | 15 | 2016 |
Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1 L Loeff*, A Kroupova*, I Asanovic, FM Boneberg, MM Pfleiderer, A Ferdigg, ... bioRxiv, 2023.04. 06.535761, 2023 | 3 | 2023 |
Microbial warfare: illuminating CRISPR adaptive immunity using single-molecule fluorescence L Loeff | 2 | 2017 |
DNA end sensing and cleavage by the Shedu anti-phage defense system L Loeff, A Walter, GT Rosalen, M Jinek bioRxiv, 2023.08. 10.552762, 2023 | 1 | 2023 |
Biophysics of RNA-Guided CRISPR Immunity L Loeff, C Joo Biophysics of RNA-Protein Interactions: A Mechanistic View, 189-210, 2019 | | 2019 |