Sikander Hayat

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Arne ElofssonScience for Life Laboratory and department of Biochemistry and Biophysics, Stockholm UniversityVerified email at bioinfo.se
Rafael Kramann, MD, PhD,RWTH Aachen University,Verified email at ukaachen.de
Volkhard HelmsSaarland University, Saarbruecken, GermanyVerified email at bioinformatik.uni-saarland.de
Patrick T. Ellinor, MD, PhDBroad Institute of MIT and Harvard, Massachusetts General Hospital, Harvard Medical SchoolVerified email at mgh.harvard.edu
Chris SanderHarvard Medical School, Broad Institute, Dana-Farber Cancer Institute, Memorial Sloan KetteringVerified email at sanderlab.org
Christian M StegmannAbsciVerified email at absci.com
Irinna PapangeliYale UniversityVerified email at yale.edu
Thomas HinzeSenior Lecturer at Friedrich Schiller University JenaVerified email at uni-jena.de
Kenichiro ImaiBiotechnology Research Institute for Drug Discovery, AISTVerified email at aist.go.jp
Paul HortonNCKU, TaiwanVerified email at iscb.org
Kentaro TomiiAISTVerified email at aist.go.jp
Yungki ParkAssociate Professor of Biochemistry, SUNY BuffaloVerified email at buffalo.edu
Peter DittrichFriedrich Schiller University JenaVerified email at minet.uni-jena.de
Marcin J. SkwarkBioinformatics Lead, InstaDeepVerified email at skwark.pl
Mirco MichelTNG Technology Consulting GmbHVerified email at tngtech.com
Konstantinos Tsirigos, PhD Bioinforma...DTU BiosustainVerified email at dtu.dk
Lutz BruschCenter for Information Services and High Performance Computing (ZIH), Technische Universität DresdenVerified email at tu-dresden.de
Tim NugentResearcher, GSR MarketsVerified email at gsr.io
David JonesProfessor of Bioinformatics, University College LondonVerified email at ucl.ac.uk
Guillermo BarturenPhD Researcher, GenyoVerified email at genyo.es

Sikander Hayat

Group Leader, Translational Data Science, RWTH Aachen University

Verified email at ukaachen.de - Homepage

single cell sequencing heart failure fibrosis kidney diseases biomarker discovery


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Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer Cell 163 (2), 506-519, 2015	1802	2015
Spatial multi-omic map of human myocardial infarction C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ... Nature 608 (7924), 766-777, 2022	301	2022
Molecular architecture of the active mitochondrial protein gate T Shiota, K Imai, J Qiu, VL Hewitt, K Tan, HH Shen, N Sakiyama, ... Science 349 (6255), 1544-1548, 2015	240	2015
TCGA Research Network. Comprehensive molecular portraits of invasive lobular breast cancer G Ciriello, ML Gatza, AH Beck, MD Wilkerson, SK Rhie, A Pastore, ... Cell 163 (2), 506-519, 2015	201	2015
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy M Chaffin, I Papangeli, B Simonson, AD Akkad, MC Hill, A Arduini, ... Nature 608 (7921), 174-180, 2022	175	2022
Integrative analysis reveals a molecular stratification of systemic autoimmune diseases G Barturen, S Babaei, F Català‐Moll, M Martínez‐Bueno, Z Makowska, ... Arthritis & rheumatology 73 (6), 1073-1085, 2021	127	2021
Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2–Mediated Myocarditis NR Tucker, M Chaffin, KC Bedi Jr, I Papangeli, AD Akkad, A Arduini, ... Circulation 142 (7), 708-710, 2020	116	2020
PconsFold: improved contact predictions improve protein models M Michel, S Hayat, MJ Skwark, C Sander, DS Marks, A Elofsson Bioinformatics 30 (17), i482-i488, 2014	114	2014
BOCTOPUS: improved topology prediction of transmembrane β barrel proteins S Hayat, A Elofsson Bioinformatics 28 (4), 516-522, 2012	94	2012
Evaluation of colorectal cancer subtypes and cell lines using deep learning J Ronen, S Hayat, A Akalin Life science alliance 2 (6), 2019	92	2019
Inclusion of dyad-repeat pattern improves topology prediction of transmembrane β-barrel proteins S Hayat, C Peters, N Shu, KD Tsirigos, A Elofsson Bioinformatics 32 (10), 1571-1573, 2016	87	2016
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner K Hoeft, GJL Schaefer, H Kim, D Schumacher, T Bleckwehl, Q Long, ... Cell Reports 42 (2), 2023	86	2023
All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences S Hayat, C Sander, DS Marks, A Elofsson Proceedings of the National Academy of Sciences 112 (17), 5413-5418, 2015	64	2015
Prediction of the burial status of transmembrane residues of helical membrane proteins Y Park, S Hayat, V Helms BMC bioinformatics 8, 1-14, 2007	57	2007
Sublethal necroptosis signaling promotes inflammation and liver cancer M Vucur, A Ghallab, AT Schneider, A Adili, M Cheng, M Castoldi, ... Immunity 56 (7), 1578-1595. e8, 2023	43	2023
Evfold. org: Evolutionary couplings and protein 3d structure prediction R Sheridan, RJ Fieldhouse, S Hayat, Y Sun, Y Antipin, L Yang, T Hopf, ... biorxiv, 021022, 2015	35	2015
TMBHMM: a frequency profile based HMM for predicting the topology of transmembrane beta barrel proteins and the exposure status of transmembrane residues NK Singh, A Goodman, P Walter, V Helms, S Hayat Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (5), 664-670, 2011	32	2011
Adult human kidney organoids originate from CD24⁺ cells and represent an advanced model for adult polycystic kidney disease Y Xu, C Kuppe, J Perales-Patón, S Hayat, J Kranz, AT Abdallah, J Nagai, ... Nature genetics 54 (11), 1690-1701, 2022	27	2022
Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure B Simonson, M Chaffin, MC Hill, O Atwa, Y Guedira, H Bhasin, AW Hall, ... Cell reports 42 (2), 2023	25	2023
Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12 X Wu, GR Schnitzler, GF Gao, B Diamond, AR Baker, B Kaplan, ... Journal of Biological Chemistry 295 (11), 3431-3446, 2020	21	2020

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