Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells PJ Paddison, AA Caudy, E Bernstein, GJ Hannon, DS Conklin Genes & development 16 (8), 948-958, 2002 | 2585 | 2002 |
RNA interference in adult mice AP McCaffrey, L Meuse, TTT Pham, DS Conklin, GJ Hannon, MA Kay Nature 418 (6893), 38-39, 2002 | 1673 | 2002 |
A resource for large-scale RNA-interference-based screens in mammals PJ Paddison, JM Silva, DS Conklin, M Schlabach, M Li, S Aruleba, ... Nature 428 (6981), 427-431, 2004 | 924 | 2004 |
14-3-3 proteins associate with cdc25 phosphatases. DS Conklin, K Galaktionov, D Beach Proceedings of the National Academy of Sciences 92 (17), 7892-7896, 1995 | 355 | 1995 |
Trm9-catalyzed tRNA modifications link translation to the DNA damage response U Begley, M Dyavaiah, A Patil, JP Rooney, D DiRenzo, CM Young, ... Molecular cell 28 (5), 860-870, 2007 | 333 | 2007 |
Germline transmission of RNAi in mice MA Carmell, L Zhang, DS Conklin, GJ Hannon, TA Rosenquist Nature structural biology 10 (2), 91-92, 2003 | 307 | 2003 |
COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae DS Conklin, JA Mcmaster, MR Culbertson, C Kung Molecular and cellular biology, 1992 | 282 | 1992 |
High-throughput selection of effective RNAi probes for gene silencing R Kumar, DS Conklin, V Mittal Genome research 13 (10), 2333-2340, 2003 | 229 | 2003 |
Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence AP Adam, A George, D Schewe, P Bragado, BV Iglesias, ... Cancer research 69 (14), 5664-5672, 2009 | 221 | 2009 |
Methods and compositions for RNA interference D Beach, E Bernstein, A Caudy, S Hammond, G Hannon, P Paddison, ... US Patent App. 10/350,798, 2004 | 159 | 2004 |
Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival AC Ranganathan, S Ojha, A Kourtidis, DS Conklin, JA Aguirre-Ghiso Cancer research 68 (9), 3260-3268, 2008 | 129 | 2008 |
RNA interference by short hairpin RNAs expressed in vertebrate cells GJ Hannon, DS Conklin mRNA Processing and Metabolism: Methods and Protocols, 255-266, 2004 | 119 | 2004 |
Lipid biology of breast cancer J Baumann, C Sevinsky, DS Conklin Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 115 | 2013 |
MaRX: an approach to genetics in mammalian cells GJ Hannon, P Sun, A Carnero, LY Xie, R Maestro, DS Conklin, D Beach Science 283 (5405), 1129-1130, 1999 | 114 | 1999 |
Mammalian viral vectors and their uses DH Beach, GJ Hannon, D Conklin, P Sun US Patent 6,255,071, 2001 | 109 | 2001 |
Interactions between gene products involved in divalent cation transport in Saccharomyces cerevisiae DS Conklin, MR Culbertson, C Kung Molecular and General Genetics MGG 244, 303-311, 1994 | 91 | 1994 |
PPARγ maintains ERBB2-positive breast cancer stem cells X Wang, Y Sun, J Wong, DS Conklin Oncogene 32 (49), 5512, 2013 | 89 | 2013 |
An RNA interference screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature A Kourtidis, R Jain, RD Carkner, C Eifert, MJ Brosnan, DS Conklin Cancer research 70 (5), 1783-1792, 2010 | 85 | 2010 |
The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes CB O'Connell, J Lončarek, P Hergert, A Kourtidis, DS Conklin, ... J Cell Biol 183 (1), 29-36, 2008 | 82 | 2008 |
Inertial microfluidic cell stretcher (iMCS): fully automated, high‐throughput, and near real‐time cell mechanotyping Y Deng, SP Davis, F Yang, KS Paulsen, M Kumar, R Sinnott DeVaux, ... Small 13 (28), 1700705, 2017 | 79 | 2017 |