| The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs N Inoue, M Ikawa, A Isotani, M Okabe Nature 434 (7030), 234-238, 2005 | 961 | 2005 |
| Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA D Mashiko, Y Fujihara, Y Satouh, H Miyata, A Isotani, M Ikawa Scientific reports 3 (1), 3355, 2013 | 461 | 2013 |
| Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse R Yamaguchi, Y Muro, A Isotani, K Tokuhiro, K Takumi, I Adham, M Ikawa, ... Biology of Reproduction 81 (1), 142-146, 2009 | 196 | 2009 |
| Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages S Kobayashi, A Isotani, N Mise, M Yamamoto, Y Fujihara, K Kaseda, ... Current Biology 16 (2), 166-172, 2006 | 177 | 2006 |
| SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia Y Fujihara, Y Satouh, N Inoue, A Isotani, M Ikawa, M Okabe Development 139 (19), 3583-3589, 2012 | 167 | 2012 |
| FISH analysis of 142 EGFP transgene integration sites into the mouse genome T Nakanishi, A Kuroiwa, S Yamada, A Isotani, A Yamashita, A Tairaka, ... Genomics 80 (6), 564-574, 2002 | 165 | 2002 |
| Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive H Miyata, Y Satouh, D Mashiko, M Muto, K Nozawa, K Shiba, Y Fujihara, ... Science 350 (6259), 442-445, 2015 | 161 | 2015 |
| HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility H Tanaka, N Iguchi, A Isotani, K Kitamura, Y Toyama, Y Matsuoka, ... Molecular and cellular biology 25 (16), 7107-7119, 2005 | 160 | 2005 |
| Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice H Miyata, JM Castaneda, Y Fujihara, Z Yu, DR Archambeault, A Isotani, ... Proceedings of the National Academy of Sciences 113 (28), 7704-7710, 2016 | 149 | 2016 |
| Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer Y Okada, Y Ueshin, A Isotani, T Saito-Fujita, H Nakashima, K Kimura, ... Nature biotechnology 25 (2), 233-237, 2007 | 137 | 2007 |
| Behavior of mouse spermatozoa in the female reproductive tract from soon after mating to the beginning of fertilization Y Muro, H Hasuwa, A Isotani, H Miyata, K Yamagata, M Ikawa, ... Biology of reproduction 94 (4), 80, 1-7, 2016 | 129 | 2016 |
| Formation of a thymus from rat ES cells in xenogeneic nude mouse↔ rat ES chimeras A Isotani, H Hatayama, K Kaseda, M Ikawa, M Okabe Genes to Cells 16 (4), 397-405, 2011 | 121 | 2011 |
| CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice A Oji, T Noda, Y Fujihara, H Miyata, YJ Kim, M Muto, K Nozawa, ... Scientific Reports 6 (1), 31666, 2016 | 107 | 2016 |
| Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice T Nakanishi, A Isotani, R Yamaguchi, M Ikawa, T Baba, SS Suarez, ... Biology of reproduction 71 (3), 959-965, 2004 | 107 | 2004 |
| OAZ-t/OAZ3 Is Essential for Rigid Connection of Sperm Tails to Heads in Mouse K Tokuhiro, A Isotani, S Yokota, Y Yano, S Oshio, M Hirose, M Wada, ... PLoS genetics 5 (11), e1000712, 2009 | 104 | 2009 |
| Testis-specific histone variant H3t gene is essential for entry into spermatogenesis J Ueda, A Harada, T Urahama, S Machida, K Maehara, M Hada, Y Makino, ... Cell reports 18 (3), 593-600, 2017 | 100 | 2017 |
| CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice Y Lu, S Oura, T Matsumura, A Oji, N Sakurai, Y Fujihara, K Shimada, ... Biology of Reproduction 101 (2), 501-511, 2019 | 90 | 2019 |
| A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice C Kokubu, K Horie, K Abe, R Ikeda, S Mizuno, Y Uno, S Ogiwara, ... Nature genetics 41 (8), 946-952, 2009 | 72 | 2009 |
| CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis SAM Young, H Miyata, Y Satouh, H Kato, K Nozawa, A Isotani, RJ Aitken, ... International journal of molecular sciences 16 (10), 24732-24750, 2015 | 51 | 2015 |
| Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX↔ XY chimeric testes A Isotani, T Nakanishi, S Kobayashi, J Lee, S Chuma, N Nakatsuji, ... Proceedings of the National Academy of Sciences 102 (11), 4039-4044, 2005 | 45 | 2005 |
