フォロー
Andrew Peat
Andrew Peat
確認したメール アドレス: gsk.com
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引用先
引用先
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules
CP Briscoe, AJ Peat, SC McKeown, DF Corbett, AS Goetz, TR Littleton, ...
British journal of pharmacology 148 (5), 619-628, 2006
4812006
Open-air alkylation reactions in photoredox-catalyzed DNA-encoded library synthesis
JP Phelan, SB Lang, J Sim, S Berritt, AJ Peat, K Billings, L Fan, ...
Journal of the American Chemical Society 141 (8), 3723-3732, 2019
2542019
Novel syntheses of tetrahydropyrroloquinolines: Applications to alkaloid synthesis
AJ Peat, SL Buchwald
Journal of the American Chemical Society 118 (5), 1028-1030, 1996
1671996
Synthesis and activity of small molecule GPR40 agonists
DM Garrido, DF Corbett, KA Dwornik, AS Goetz, TR Littleton, ...
Bioorganic & Medicinal Chemistry Letters 16 (7), 1840-1845, 2006
1532006
Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor
SC McKeown, DF Corbett, AS Goetz, TR Littleton, E Bigham, CP Briscoe, ...
Bioorganic & medicinal chemistry letters 17 (6), 1584-1589, 2007
902007
Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors
AJ Peat, JA Boucheron, SH Dickerson, D Garrido, W Mills, J Peckham, ...
Bioorganic & medicinal chemistry letters 14 (9), 2121-2125, 2004
902004
Titanocene-based method for indole synthesis
K Aoki, AJ Peat, SL Buchwald
Journal of the American Chemical Society 120 (13), 3068-3073, 1998
711998
Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1
FX Tavares, KA Al-Barazanji, EC Bigham, MJ Bishop, CS Britt, DL Carlton, ...
Journal of medicinal chemistry 49 (24), 7095-7107, 2006
702006
Synthesis and evaluation of novel heterocyclic inhibitors of GSK-3
TL Smalley Jr, AJ Peat, JA Boucheron, S Dickerson, D Garrido, ...
Bioorganic & medicinal chemistry letters 16 (8), 2091-2094, 2006
642006
The discovery and optimization of pyrimidinone-containing MCH R1 antagonists
DL Hertzog, KA Al-Barazanji, EC Bigham, MJ Bishop, CS Britt, DL Carlton, ...
Bioorganic & medicinal chemistry letters 16 (18), 4723-4727, 2006
622006
Novel GSK-3 inhibitors with improved cellular activity
AJ Peat, D Garrido, JA Boucheron, SL Schweiker, SH Dickerson, ...
Bioorganic & medicinal chemistry letters 14 (9), 2127-2130, 2004
622004
Rational design of potent non-nucleoside inhibitors of HIV-1 reverse transcriptase
P Chong, P Sebahar, M Youngman, D Garrido, H Zhang, EL Stewart, ...
Journal of medicinal chemistry 55 (23), 10601-10609, 2012
602012
Hepatitis C replication inhibitors that target the viral NS4B protein
JF Miller, PY Chong, JB Shotwell, JG Catalano, VWF Tai, J Fang, ...
Journal of medicinal chemistry 57 (5), 2107-2120, 2014
592014
Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase
A Maynard, RM Crosby, B Ellis, R Hamatake, Z Hong, BA Johns, ...
Journal of Medicinal Chemistry 57 (5), 1902-1913, 2014
572014
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization
JB Shotwell, S Baskaran, P Chong, KL Creech, RM Crosby, H Dickson, ...
ACS Medicinal Chemistry Letters 3 (7), 565-569, 2012
552012
Synthesis and reactions of 3-(bromomethyl)-1-carbethoxy-4-iodoindole: The preparation of 3, 4-differentially substituted indoles
JH Tidwell, AJ Peat, SL Buchwald
The Journal of Organic Chemistry 59 (23), 7164-7168, 1994
551994
Pyrazolopyrimidines as kinase inhibitors
S Dickerson, D Garrido, W Mills, K Kano, A Peat, S Thomson, J Wilson, ...
US Patent App. 10/521,909, 2006
532006
Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
PY Chong, JB Shotwell, J Miller, DJ Price, A Maynard, C Voitenleitner, ...
Journal of Medicinal Chemistry 62 (7), 3254-3267, 2019
512019
Multi-modal imaging with a toolbox of influenza A reporter viruses
V Tran, DS Poole, JJ Jeffery, TP Sheahan, D Creech, A Yevtodiyenko, ...
Viruses 7 (10), 5319-5327, 2015
432015
A Combined Zirconocene Benzyne− Palladium Cross-Coupling Route to Substituted Biphenyls and Terphenyls
M Frid, D Perez, AJ Peat, SL Buchwald
Journal of the American Chemical Society 121 (40), 9469-9470, 1999
411999
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