Frequent pathway mutations of splicing machinery in myelodysplasia K Yoshida, M Sanada, Y Shiraishi, D Nowak, Y Nagata, R Yamamoto, ... Nature 478 (7367), 64-69, 2011 | 2331 | 2011 |
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators A Fujimoto, Y Totoki, T Abe, KA Boroevich, F Hosoda, HH Nguyen, M Aoki, ... Nature genetics 44 (7), 760-764, 2012 | 957 | 2012 |
Hybrid Petri net representation of gene regulatory network H Matsuno, A Doi, M Nagasaki, S Miyano Biocomputing 2000, 341-352, 1999 | 454 | 1999 |
Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals M Nagasaki, J Yasuda, F Katsuoka, N Nariai, K Kojima, Y Kawai, ... Nature communications 6 (1), 8018, 2015 | 424 | 2015 |
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms A Kon, LY Shih, M Minamino, M Sanada, Y Shiraishi, Y Nagata, ... Nature genetics 45 (10), 1232-1237, 2013 | 424 | 2013 |
A comprehensive genomic analysis reveals the genetic landscape of mitochondrial respiratory chain complex deficiencies M Kohda, Y Tokuzawa, Y Kishita, H Nyuzuki, Y Moriyama, Y Mizuno, ... PLoS genetics 12 (1), e1005679, 2016 | 286 | 2016 |
The Tohoku medical megabank project: design and mission S Kuriyama, N Yaegashi, F Nagami, T Arai, Y Kawaguchi, N Osumi, ... Journal of epidemiology 26 (9), 493-511, 2016 | 281 | 2016 |
Genomic Object Net: I. A platform for modelling and simulating biopathways. M Nagasaki, H Matsuno, S Miyano Applied bioinformatics 2 (3), 181-184, 2003 | 161 | 2003 |
Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma M Yamauchi, R Yamaguchi, A Nakata, T Kohno, M Nagasaki, ... Public Library of Science 7 (9), e43923, 2012 | 155 | 2012 |
Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals Y Kawai, T Mimori, K Kojima, N Nariai, I Danjoh, R Saito, J Yasuda, ... Journal of human genetics 60 (10), 581-587, 2015 | 143 | 2015 |
Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing A Fujimoto, H Nakagawa, N Hosono, K Nakano, T Abe, KA Boroevich, ... Nature genetics 42 (11), 931-936, 2010 | 141 | 2010 |
Constructing biological pathway models with hybrid functional Petri nets S Fujita, H Matsuno, M Nagasaki, S Miyano In silico biology 4 (3), 271-291, 2004 | 134 | 2004 |
3.5 KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome S Tadaka, F Katsuoka, M Ueki, K Kojima, S Makino, S Saito, A Otsuki, ... Human Genome Variation 6 (1), 28, 2019 | 126 | 2019 |
Cohort profile: Tohoku medical megabank project birth and three-generation cohort study (TMM BirThree cohort study): rationale, progress and perspective S Kuriyama, H Metoki, M Kikuya, T Obara, M Ishikuro, C Yamanaka, ... International journal of epidemiology 49 (1), 18-19m, 2020 | 125 | 2020 |
Genome-wide association study identifies TLL1 variant associated with development of hepatocellular carcinoma after eradication of hepatitis C virus infection K Matsuura, H Sawai, K Ikeo, S Ogawa, E Iio, M Isogawa, N Shimada, ... Gastroenterology 152 (6), 1383-1394, 2017 | 118* | 2017 |
iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing Y Yamaguchi-Kabata, N Nariai, Y Kawai, Y Sato, K Kojima, M Tateno, ... Human genome variation 2 (1), 1-4, 2015 | 112 | 2015 |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter … Y Kakuta, Y Kawai, D Okamoto, T Takagawa, K Ikeya, H Sakuraba, ... Journal of gastroenterology 53, 1065-1078, 2018 | 111 | 2018 |
Cell illustrator 4.0: a computational platform for systems biology M Nagasaki, A Saito, E Jeong, C Li, K Kojima, E Ikeda, S Miyano In silico biology 10 (1-2), 5-26, 2010 | 109 | 2010 |
A versatile Petri net based architecture for modeling and simulation of complex biological processes M Nagasaki, A Doi, H Matsuno, S Miyano Genome informatics 15 (1), 180-197, 2004 | 99 | 2004 |
Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing Y Shibuya, H Tokunaga, S Saito, K Shimokawa, F Katsuoka, L Bin, ... Genes, Chromosomes and Cancer 57 (2), 51-60, 2018 | 97 | 2018 |