Tryprostatin A, a specific and novel inhibitor of microtubule assembly T Usui, M Kondoh, CB Cui, T Mayumi, H OSADA Biochemical Journal 333 (3), 543-548, 1998 | 281 | 1998 |
Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions H Maekawa, T Usui, M Knop, E Schiebel The EMBO journal, 2003 | 187 | 2003 |
Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes S Ganesh, KL Agarwala, K Ueda, T Akagi, K Shoda, T Usui, T Hashikawa, ... Human molecular genetics 9 (15), 2251-2261, 2000 | 177 | 2000 |
Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases K Abe, M Yoshida, T Usui, S Horinouchi, T Beppu Experimental cell research 192 (1), 122-127, 1991 | 159 | 1991 |
Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a. T Usui, M Yoshida, K Abe, H Osada, K Isono, T Beppu The Journal of cell biology 115 (5), 1275-1282, 1991 | 151 | 1991 |
Asymmetric, stereocontrolled total synthesis of (+) and (−)-spirotryprostatin B via a diastereoselective azomethine ylide [1, 3]-dipolar cycloaddition reaction PR Sebahar, H Osada, T Usui, RM Williams Tetrahedron 58 (32), 6311-6322, 2002 | 149 | 2002 |
A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5 J Nakazawa, J Yajima, T Usui, M Ueki, A Takatsuki, M Imoto, ... Chemistry & biology 10 (2), 131-137, 2003 | 147 | 2003 |
The anticancer natural product pironetin selectively targets Lys352 of α-tubulin T Usui, H Watanabe, H Nakayama, Y Tada, N Kanoh, M Kondoh, T Asao, ... Chemistry & biology 11 (6), 799-806, 2004 | 133 | 2004 |
Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition M Sodeoka, R Sampe, S Kojima, Y Baba, T Usui, K Ueda, H Osada Journal of medicinal chemistry 44 (20), 3216-3222, 2001 | 127 | 2001 |
Cell cycle arrest and antitumor activity of pironetin and its derivatives M Kondoh, T Usui, S Kobayashi, K Tsuchiya, K Nishikawa, T Nishikiori, ... Cancer letters 126 (1), 29-32, 1998 | 124 | 1998 |
Synthesis and structure–activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2, 5-dione structure Y Yamazaki, K Tanaka, B Nicholson, G Deyanat-Yazdi, B Potts, T Yoshida, ... Journal of medicinal chemistry 55 (3), 1056-1071, 2012 | 122 | 2012 |
Isolation of New Protein Phosphatase Inhibitors from Two Cyanobacteria Species, Planktothrix spp. T Sano, T Usui, K Ueda, H Osada, K Kaya Journal of natural products 64 (8), 1052-1055, 2001 | 115 | 2001 |
Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues H Wang, T Usui, H Osada, A Ganesan Journal of medicinal chemistry 43 (8), 1577-1585, 2000 | 104 | 2000 |
Identification of Cytochrome P450s Required for Fumitremorgin Biosynthesis in Aspergillus fumigatus N Kato, H Suzuki, H Takagi, Y Asami, H Kakeya, M Uramoto, T Usui, ... ChemBioChem 10 (5), 920-928, 2009 | 101 | 2009 |
Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action M Muroi, S Kazami, K Noda, H Kondo, H Takayama, M Kawatani, T Usui, ... Chemistry & biology 17 (5), 460-470, 2010 | 95 | 2010 |
Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin M KONDOH, T USUI, T NISHIKIORI, T MAYUMI, H OSADA Biochemical Journal 340 (2), 411-416, 1999 | 95 | 1999 |
The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorage T Usui, H Maekawa, G Pereira, E Schiebel The EMBO journal, 2003 | 93 | 2003 |
Amphidinolide H, a potent cytotoxic macrolide, covalently binds on actin subdomain 4 and stabilizes actin filament T Usui, S Kazami, N Dohmae, Y Mashimo, H Kondo, M Tsuda, ... Chemistry & biology 11 (9), 1269-1277, 2004 | 92 | 2004 |
Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A Y Miyamoto, K Machida, M Mizunuma, Y Emoto, N Sato, K Miyahara, ... Journal of Biological Chemistry 277 (32), 28810-28814, 2002 | 87 | 2002 |
Synthesis and evaluation of microtubule assembly inhibition and cytotoxicity of prenylated derivatives of cyclo-L-Trp-L-Pro JF Sanz-Cervera, EM Stocking, T Usui, H Osada, RM Williams Bioorganic & medicinal chemistry 8 (10), 2407-2415, 2000 | 74 | 2000 |