フォロー
Jeffrey Hanson
Jeffrey Hanson
Director, Sutro Biopharma
確認したメール アドレス: sutrobio.com
タイトル
引用先
引用先
Illuminating the mechanistic roles of enzyme conformational dynamics
JA Hanson, K Duderstadt, LP Watkins, S Bhattacharyya, J Brokaw, ...
Proceedings of the National Academy of Sciences 104 (46), 18055-18060, 2007
3162007
A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell‐free protein synthesis systems
Q Cai, JA Hanson, AR Steiner, C Tran, MR Masikat, R Chen, JF Zawada, ...
Biotechnology progress 31 (3), 823-831, 2015
952015
Engagement of arginine finger to ATP triggers large conformational changes in NtrC1 AAA+ ATPase for remodeling bacterial RNA polymerase
B Chen, TA Sysoeva, S Chowdhury, L Guo, S De Carlo, JA Hanson, ...
Structure 18 (11), 1420-1430, 2010
762010
RAMPED-UP NMR: multiplexed NMR-based screening for drug discovery
ER Zartler, J Hanson, BE Jones, AD Kline, G Martin, H Mo, MJ Shapiro, ...
Journal of the American Chemical Society 125 (36), 10941-10946, 2003
612003
Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001
CL Abrahams, X Li, M Embry, A Yu, S Krimm, S Krueger, NY Greenland, ...
Oncotarget 9 (102), 37700, 2018
482018
Dynamic Active-Site Protection by the M. tuberculosis Protein Tyrosine Phosphatase PtpB Lid Domain
EM Flynn, JA Hanson, T Alber, H Yang
Journal of the American Chemical Society 132 (13), 4772-4780, 2010
352010
Direct Mg2+ binding activates adenylate kinase from Escherichia coli
YW Tan, JA Hanson, H Yang
Journal of biological chemistry 284 (5), 3306-3313, 2009
342009
Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents
J Almaliti, B Miller, H Pietraszkiewicz, E Glukhov, CB Naman, T Kline, ...
European journal of medicinal chemistry 161, 416-432, 2019
242019
High frequency of CD74 expression in lymphomas: implications for targeted therapy using a novel anti‐CD74‐drug conjugate
S Zhao, A Molina, A Yu, J Hanson, H Cheung, X Li, Y Natkunam
The Journal of Pathology: Clinical Research 5 (1), 12-24, 2019
202019
Toward a ferrous iron-cleavable linker for antibody–drug conjugates
B Spangler, T Kline, J Hanson, X Li, S Zhou, JA Wells, AK Sato, ...
Molecular pharmaceutics 15 (5), 2054-2059, 2018
192018
Structural distributions from single-molecule measurements as a tool for molecular mechanics
JA Hanson, J Brokaw, CC Hayden, JW Chu, H Yang
Chemical physics 396, 61-71, 2012
192012
Confocal single-molecule FRET for protein conformational dynamics
YW Tan, JA Hanson, JW Chu, H Yang
Protein Dynamics: Methods and Protocols, 51-62, 2014
152014
Discovery of STRO-002, a novel homogeneous ADC targeting folate receptor alpha, for the treatment of ovarian and endometrial cancers
X Li, S Zhou, CL Abrahams, S Krimm, J Smith, K Bajjuri, HT Stephenson, ...
Molecular Cancer Therapeutics 22 (2), 155-167, 2023
142023
Development of an E. coli strain for cell‐free ADC manufacturing
D Groff, NA Carlos, R Chen, JA Hanson, S Liang, S Armstrong, X Li, ...
Biotechnology and Bioengineering 119 (1), 162-175, 2022
122022
Discovery and activity of STRO-002, a novel ADC targeting folate receptor alpha for ovarian and endometrial cancer
X Li, C Abrahams, S Zhou, S Krimm, R Henningsen, H Stephenson, ...
Cancer Res 78 (13 Supplement), 1782, 2018
122018
Abstract NT-090: Preclinical activity and safety of STRO-002, a novel ADC targeting folate receptor alpha for ovarian and endometrial cancer
C Abrahams, S Krimm, X Li, S Zhou, J Hanson, MR Masikat, K Bajjuri, ...
Clinical Cancer Research 25 (22_Supplement), NT-090-NT-090, 2019
72019
An integrated in vivo/in vitro protein production platform for site-specific antibody drug conjugates
J Hanson, D Groff, A Carlos, H Usman, K Fong, A Yu, S Armstrong, ...
Bioengineering 10 (3), 304, 2023
22023
Synthetic pathways for biofuel synthesis
MCY Chang, B Bond-Watts, M Wen, JA Hanson
US Patent App. 13/708,824, 2014
22014
Preclinical activity and safety of STRO-002, a novel ADC targeting folate receptor alpha for ovarian cancer
V De Almeida, C Abrahams, W Solis, X Li, T Kline, J Hanson, MR Masikat, ...
Gynecologic Oncology 149, 50, 2018
12018
Quantitative in vitro Biochemistry, one molecule at a time
JA Hanson, H Yang
Quantitative Biology, 111-130, 2012
12012
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論文 1–20