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Luhan Yang
Luhan Yang
CEO, QihanBio
Verified email at qihanbio.com - Homepage
Title
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Cited by
Year
RNA-guided human genome engineering via Cas9
P Mali, L Yang, KM Esvelt, J Aach, M Guell, JE DiCarlo, JE Norville, ...
Science 339 (6121), 823-826, 2013
115042013
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ...
Nature biotechnology 31 (9), 833-838, 2013
22832013
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ...
Nature medicine 20 (6), 616-623, 2014
8962014
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee, HY Zhao, Y Wang, Y Kan, ...
Science 357 (6357), 1303-1307, 2017
7602017
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
L Yang, M GŁell, D Niu, H George, E Lesha, D Grishin, J Aach, E Shrock, ...
Science 350 (6264), 1101-1104, 2015
7002015
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ...
Science 349 (6251), 982-986, 2015
6322015
Optimization of scarless human stem cell genome editing
L Yang, M Guell, S Byrne, JL Yang, A De Los Angeles, P Mali, J Aach, ...
Nucleic acids research 41 (19), 9049-9061, 2013
4962013
RNA-Guided Human Genome Engineering
GM Church, L Yang
US Patent App. 14/318,933, 2014
3682014
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church
Nucleic acids research 40 (15), e117-e117, 2012
2952012
The genome project-write
JD Boeke, G Church, A Hessel, NJ Kelley, A Arkin, Y Cai, R Carlson, ...
Science 353 (6295), 126-127, 2016
2872016
A public resource facilitating clinical use of genomes
MP Ball, JV Thakuria, AW Zaranek, T Clegg, AM Rosenbaum, X Wu, ...
Proceedings of the National Academy of Sciences 109 (30), 11920-11927, 2012
2232012
Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA)
M GŁell, L Yang, GM Church
Bioinformatics 30 (20), 2968-2970, 2014
1752014
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells
L Yang, D Grishin, G Wang, J Aach, CZ Zhang, R Chari, J Homsy, X Cai, ...
Nature communications 5 (1), 5507, 2014
1692014
RNA-Guided Human Genome Engineering
GM Church, P Mali, L Yang
US Patent App. 14/681,510, 2017
1452017
Extensive germline genome engineering in pigs
Y Yue, W Xu, Y Kan, HY Zhao, Y Zhou, X Song, J Wu, J Xiong, ...
Nature Biomedical Engineering 5 (2), 134-143, 2021
1412021
Genome engineering
GM Church, L Yang, M Guell, JL Yang
US Patent 11,306,328, 2022
1392022
Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies
G Wang, L Yang, D Grishin, X Rios, LY Ye, Y Hu, K Li, D Zhang, ...
Nature protocols 12 (1), 88-103, 2017
1282017
Genome engineering
GM Church, L Yang, M Guell, JL Yang
US Patent 10,563,225, 2020
1182020
Engineering and optimising deaminase fusions for genome editing
L Yang, AW Briggs, WL Chew, P Mali, M Guell, J Aach, DB Goodman, ...
Nature Communications 7 (1), 13330, 2016
1052016
RNA-guided human genome engineering
GM Church, L Yang
US Patent 10,273,501, 2019
1042019
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