Masashi Maekawa
Masashi Maekawa
Senior Researcher, Daiichi Sankyo
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Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol
M Maekawa, GD Fairn
Journal of cell science 128 (7), 1422-1433, 2015
Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation
Y Egami, T Taguchi, M Maekawa, H Arai, N Araki
Frontiers in physiology 5, 110361, 2014
Molecular probes to visualize the location, organization and dynamics of lipids
M Maekawa, GD Fairn
Journal of cell science 127 (22), 4801-4812, 2014
Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis
M Maekawa, S Terasaka, Y Mochizuki, K Kawai, Y Ikeda, N Araki, ...
Proceedings of the National Academy of Sciences 111 (11), E978-E987, 2014
Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane
K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ...
Molecular and cellular biology 36 (2), 363-374, 2016
Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
T Hirama, SM Lu, JG Kay, M Maekawa, MM Kozlov, S Grinstein, GD Fairn
Nature communications 8 (1), 1393, 2017
Domain 4 (D4) of perfringolysin O to visualize cholesterol in cellular membranes—The update
M Maekawa
Sensors 17 (3), 504, 2017
Perfringolysin O theta toxin as a tool to monitor the distribution and inhomogeneity of cholesterol in cellular membranes
M Maekawa, Y Yang, GD Fairn
Toxins 8 (3), 67, 2016
The Cullin-3–Rbx1–KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB
I Kovačević, T Sakaue, J Majoleť, MC Pronk, M Maekawa, D Geerts, ...
Journal of cell Biology 217 (3), 1015-1032, 2018
Cullin‐3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2‐positive breast cancer cells
A Murakami, M Maekawa, K Kawai, J Nakayama, N Araki, K Semba, ...
Cancer science 110 (2), 650-661, 2019
Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine
M Maekawa, M Lee, K Wei, ND Ridgway, GD Fairn
Scientific reports 6 (1), 35762, 2016
Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells
M Maekawa, K Tanigawa, T Sakaue, H Hiyoshi, E Kubota, T Joh, ...
Biology open 6 (11), 1707-1719, 2017
Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism
K Takahashi, S Yoshina, M Masashi, W Ito, T Inoue, H Shiwaku, H Arai, ...
PLoS One 4 (1), e4104, 2009
SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9
K Tanigawa, M Maekawa, T Kiyoi, J Nakayama, R Kitazawa, S Kitazawa, ...
Journal of Cellular Physiology 234 (10), 17280-17294, 2019
The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD
A Uematsu, K Kido, H Takahashi, C Takahashi, Y Yanagihara, N Saeki, ...
Journal of Biological Chemistry 294 (38), 14135-14148, 2019
Functional analysis of GS28, an intra‐Golgi SNARE, in Caenorhabditis elegans
M Maekawa, T Inoue, H Kobuna, T Nishimura, K Gengyo‐Ando, S Mitani, ...
Genes to cells 14 (8), 1003-1013, 2009
SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex
R Watanabe, M Maekawa, M Hieda, T Taguchi, N Miura, T Kikugawa, ...
Molecular Biology of the Cell, mbc. E19-08-0456, 2020
The roles of SPOP in DNA damage response and DNA replication
M Maekawa, S Higashiyama
International journal of molecular sciences 21 (19), 7293, 2020
Neddylated Cullin 3 is required for vascular endothelial‐cadherin‐mediated endothelial barrier function
T Sakaue, A Fujisaki, H Nakayama, M Maekawa, H Hiyoshi, E Kubota, ...
Cancer science 108 (2), 208-215, 2017
PSMA‐positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state
R Watanabe, M Maekawa, T Kiyoi, M Kurata, N Miura, T Kikugawa, ...
The Prostate 81 (16), 1390-1401, 2021
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