| Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts GN Pandian, J Taniguchi, S Junetha, S Sato, L Han, A Saha, ... Scientific reports 4 (1), 3843, 2014 | 71 | 2014 |
| Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts GN Pandian, S Sato, C Anandhakumar, J Taniguchi, K Takashima, J Syed, ... ACS chemical biology 9 (12), 2729-2736, 2014 | 50 | 2014 |
| Targeting 24 bp within telomere repeat sequences with tandem tetramer pyrrole–imidazole polyamide probes Y Kawamoto, Y Kawamoto Synthesis and Biological Evaluation of Pyrrole–Imidazole Polyamide Probes …, 2019 | 47 | 2019 |
| A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell L Han, GN Pandian, S Junetha, S Sato, C Anandhakumar, J Taniguchi, ... Angew. Chem. Int. Ed 52, 13410-13413, 2013 | 44 | 2013 |
| A synthetic DNA‐binding domain guides distinct chromatin‐modifying small molecules to activate an identical gene network L Han, GN Pandian, A Chandran, S Sato, J Taniguchi, G Kashiwazaki, ... Angewandte Chemie 127 (30), 8824-8827, 2015 | 41 | 2015 |
| Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide J Syed, GN Pandian, S Sato, J Taniguchi, A Chandran, K Hashiya, ... Chemistry & biology 21 (10), 1370-1380, 2014 | 40 | 2014 |
| Next‐Generation Sequencing Studies Guide the Design of Pyrrole‐Imidazole Polyamides with Improved Binding Specificity by the Addition of β‐Alanine C Anandhakumar, Y Li, S Kizaki, GN Pandian, K Hashiya, T Bando, ... ChemBioChem 15 (18), 2647-2651, 2014 | 29 | 2014 |
| Advancing small‐molecule‐based chemical biology with next‐generation sequencing technologies C Anandhakumar, S Kizaki, T Bando, GN Pandian, H Sugiyama ChemBioChem 16 (1), 20-38, 2015 | 27 | 2015 |
| A synthetic transcriptional activator of genes associated with the retina in human dermal fibroblasts J Syed, A Chandran, GN Pandian, J Taniguchi, S Sato, K Hashiya, ... ChemBioChem 16 (10), 1497-1501, 2015 | 21 | 2015 |
| Decitabine increases neoantigen and cancer testis antigen expression to enhance T-cell–mediated toxicity against glioblastoma R Ma, M Rei, I Woodhouse, K Ferris, S Kirschner, A Chandran, U Gileadi, ... Neuro-oncology 24 (12), 2093-2106, 2022 | 20 | 2022 |
| Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing A Chandran, J Syed, RD Taylor, G Kashiwazaki, S Sato, K Hashiya, ... Nucleic Acids Research 44 (9), 4014-4024, 2016 | 19 | 2016 |
| Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole–Imidazole Polyamide seco‐CBI Conjugates RD Taylor, A Chandran, G Kashiwazaki, K Hashiya, T Bando, H Nagase, ... Chemistry–A European Journal 21 (42), 14996-15003, 2015 | 17 | 2015 |
| Hepatocyte mARC1 promotes fatty liver disease LC Lewis, L Chen, LS Hameed, RR Kitchen, C Maroteau, SR Nagarajan, ... JHEP Reports 5 (5), 100693, 2023 | 16 | 2023 |
| Expression profile of toll-like receptor 2 mRNA in selected tissues of shark (Chiloscyllium sp.) C Anandhakumar, V Lavanya, G Pradheepa, KG Tirumurugaan, GD Raj, ... Fish & shellfish immunology 33 (5), 1174-1182, 2012 | 16 | 2012 |
| Identification of binding targets of a pyrrole-imidazole polyamide KR12 in the LS180 colorectal cancer genome J Lin, K Hiraoka, T Watanabe, T Kuo, Y Shinozaki, A Takatori, ... PLoS One 11 (10), e0165581, 2016 | 14 | 2016 |
| Comparative Analysis of DNA‐Binding Selectivity of Hairpin and Cyclic Pyrrole‐Imidazole Polyamides Based on Next‐Generation Sequencing G Kashiwazaki, A Chandran, S Asamitsu, T Kawase, Y Kawamoto, ... ChemBioChem 17 (18), 1752-1758, 2016 | 13 | 2016 |
| RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons S Asamitsu, Y Yabuki, K Matsuo, M Kawasaki, Y Hirose, G Kashiwazaki, ... Science Advances 9 (8), eade2035, 2023 | 11 | 2023 |
| Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection J Cheng, P Siejka-Zielińska, Y Liu, A Chandran, S Kriaucionis, CX Song Nucleic acids research 49 (13), e76-e76, 2021 | 9 | 2021 |
| Genome‐Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High‐Throughput Sequencing A Chandran, J Syed, Y Li, S Sato, T Bando, H Sugiyama ChemBioChem 17 (20), 1905-1910, 2016 | 8 | 2016 |
| Sequence-specific DNA binding by long hairpin pyrrole–imidazole polyamides containing an 8-amino-3, 6-dioxaoctanoic acid unit Y Sawatani, G Kashiwazaki, A Chandran, S Asamitsu, C Guo, S Sato, ... Bioorganic & Medicinal Chemistry 24 (16), 3603-3611, 2016 | 8 | 2016 |
Hiroshi SugiyamaKyoto University確認したメール アドレス: kuchem.kyoto-u.ac.jp
