Accurate design of co-assembling multi-component protein nanomaterials NP King, JB Bale, W Sheffler, DE McNamara, S Gonen, T Gonen, ... Nature 510 (7503), 103-108, 2014 | 604 | 2014 |
Computational design of self-assembling cyclic protein homo-oligomers JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ... Nature chemistry 9 (4), 353-360, 2017 | 154 | 2017 |
MLKL requires the inositol phosphate code to execute necroptosis CM Dovey, J Diep, BP Clarke, AT Hale, DE McNamara, H Guo, NW Brown, ... Molecular cell 70 (5), 936-948. e7, 2018 | 140 | 2018 |
Alanine scanning mutagenesis identifies an asparagine–arginine–lysine triad essential to assembly of the shell of the Pdu microcompartment S Sinha, S Cheng, YW Sung, DE McNamara, MR Sawaya, TO Yeates, ... Journal of molecular biology 426 (12), 2328-2345, 2014 | 67 | 2014 |
Intrinsic instability of BOK enables membrane permeabilization in apoptosis JH Zheng, CR Grace, CD Guibao, DE McNamara, F Llambi, YM Wang, ... Cell reports 23 (7), 2083-2094. e6, 2018 | 50 | 2018 |
Direct activation of human MLKL by a select repertoire of inositol phosphate metabolites DE McNamara, CM Dovey, AT Hale, G Quarato, CR Grace, CD Guibao, ... Cell chemical biology 26 (6), 863-877. e7, 2019 | 38 | 2019 |
Structures of potent anticancer compounds bound to tubulin DE McNamara, S Senese, TO Yeates, JZ Torres Protein Science 24 (7), 1164-1172, 2015 | 27 | 2015 |
Investigating the impact of bisphosphonates and structurally related compounds on bacteria containing conjugative plasmids RP Nash, DE McNamara, WK Ballentine III, SW Matson, MR Redinbo Biochemical and biophysical research communications 424 (4), 697-703, 2012 | 24 | 2012 |
Structural basis of BAK activation in mitochondrial apoptosis initiation G Singh, CD Guibao, J Seetharaman, A Aggarwal, CR Grace, ... Nature Communications 13 (1), 250, 2022 | 21 | 2022 |
Functional characterization of the multidomain F plasmid TraI relaxase-helicase Y Cheng, DE McNamara, MJ Miley, RP Nash, MR Redinbo Journal of Biological Chemistry 286 (14), 12670-12682, 2011 | 21 | 2011 |
Structure of dihydromethanopterin reductase, a cubic protein cage for redox transfer DE McNamara, D Cascio, J Jorda, C Bustos, TC Wang, ME Rasche, ... Journal of Biological Chemistry 289 (13), 8852-8864, 2014 | 17 | 2014 |
Geometric lessons and design strategies for nanoscale protein cages J Laniado, KA Cannon, JE Miller, MR Sawaya, DE McNamara, TO Yeates ACS nano 15 (3), 4277-4286, 2021 | 16 | 2021 |
Characterization of MLKL-mediated plasma membrane rupture in necroptosis DE McNamara, G Quarato, CS Guy, DR Green, T Moldoveanu JoVE (Journal of Visualized Experiments), e58088, 2018 | 9 | 2018 |
Tubulin-binding compounds, compositions and uses related thereto J Torres, R Damoiseaux, TO Yeates, S Senese, DE McNamara, YC Lo US Patent 10,913,750, 2021 | 1 | 2021 |
TWO-STEP BAK ACTIVATION INITIATES MITOCHONDRIAL APOPTOSIS G Singh, S Vaithiyalingam, J Min, B Waddell, C Guibao, D McNamara, ... PROTEIN SCIENCE 28, 35-36, 2019 | | 2019 |
Tubulin-binding compounds, compositions and uses related thereto J Torres, R Damoiseaux, TO Yeates, S Senese, DE McNamara, YC Lo US Patent App. 15/577,551, 2018 | | 2018 |
Structural Studies and Engineering of Proteinaceous Assemblies DE McNamara UCLA, 2015 | | 2015 |
Structure of Dihydromethanopterin Reductase: Redox Transfer in a Cubic Protein Cage DE McNamara, D Cascio, J Jorda, C Bustos, TC Wang, ME Rasche, ... PROTEIN SCIENCE 23, 206-206, 2014 | | 2014 |
Symmetry-Based Design and Structure of Self-Assembling Protein Cages and Nanomaterials YT Lai, NP King, W Sheffler, DE McNamara, JB Bale, D Baker, TO Yeates Biophysical Journal 106 (2), 445a, 2014 | | 2014 |
The Protein Shell of the Ethanolamine Utilization Microcompartment is a Redox-Sensitive Barrier M Thompson, D Cascio, J Jorda, C Crowley, J Kopstein, J Whitelegge, ... PROTEIN SCIENCE 21, 125-125, 2012 | | 2012 |