The NLRP3 inflammasome promotes renal inflammation and contributes to CKD A Vilaysane, J Chun, ME Seamone, W Wang, R Chin, S Hirota, Y Li, ... Journal of the American Society of Nephrology 21 (10), 1732-1744, 2010 | 580 | 2010 |
Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium W Wang, X Wang, J Chun, A Vilaysane, S Clark, G French, NA Bracey, ... The Journal of Immunology 190 (3), 1239-1249, 2013 | 261 | 2013 |
Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome NA Bracey, B Gershkovich, J Chun, A Vilaysane, HC Meijndert, JR Wright, ... Journal of Biological Chemistry 289 (28), 19571-19584, 2014 | 154 | 2014 |
Shiga toxin/lipopolysaccharide activates caspase-4 and gasdermin D to trigger mitochondrial reactive oxygen species upstream of the NLRP3 inflammasome JM Platnich, H Chung, A Lau, CF Sandall, A Bondzi-Simpson, HM Chen, ... Cell reports 25 (6), 1525-1536. e7, 2018 | 140 | 2018 |
GBF1, a cis-Golgi and VTCs-localized ARF-GEF, is implicated in ER-to-Golgi protein traffic X Zhao, A Claude, J Chun, DJ Shields, JF Presley, P Melançon Journal of cell science 119 (18), 3743-3753, 2006 | 121 | 2006 |
Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi … F Manolea, A Claude, J Chun, J Rosas, P Melançon Molecular biology of the cell 19 (2), 523-535, 2008 | 116 | 2008 |
Characterization of class I and II ADP-ribosylation factors (Arfs) in live cells: GDP-bound class II Arfs associate with the ER-Golgi intermediate compartment independently of GBF1 J Chun, Z Shapovalova, SY Dejgaard, JF Presley, P Melançon Molecular biology of the cell 19 (8), 3488-3500, 2008 | 103 | 2008 |
NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis H Chung, A Vilaysane, A Lau, M Stahl, V Morampudi, A Bondzi-Simpson, ... Cell Death & Differentiation 23 (8), 1331-1346, 2016 | 102 | 2016 |
Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury A Lau, H Chung, T Komada, JM Platnich, CF Sandall, SR Choudhury, ... The Journal of clinical investigation 128 (7), 2894-2913, 2018 | 95 | 2018 |
Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity J Chun, JY Zhang, MS Wilkins, B Subramanian, C Riella, JM Magraner, ... Proceedings of the National Academy of Sciences 116 (9), 3712-3721, 2019 | 72 | 2019 |
NLRP3 localizes to the tubular epithelium in human kidney and correlates with outcome in IgA nephropathy J Chun, H Chung, X Wang, R Barry, ZM Taheri, JM Platnich, SB Ahmed, ... Scientific reports 6 (1), 24667, 2016 | 67 | 2016 |
Arf3 Is Activated Uniquely at the trans-Golgi Network by Brefeldin A-inhibited Guanine Nucleotide Exchange Factors F Manolea, J Chun, DW Chen, I Clarke, N Summerfeldt, JB Dacks, ... Molecular biology of the cell 21 (11), 1836-1849, 2010 | 66 | 2010 |
Contributions of rare gene variants to familial and sporadic FSGS M Wang, J Chun, G Genovese, AU Knob, A Benjamin, MS Wilkins, ... Journal of the American Society of Nephrology 30 (9), 1625-1640, 2019 | 47 | 2019 |
Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury A Lau, JJ Rahn, M Chappellaz, H Chung, H Benediktsson, D Bihan, ... Science advances 8 (5), eabm0142, 2022 | 36 | 2022 |
Phosphorylation of Cdc25C by pp90Rsk Contributes to a G2 Cell Cycle Arrest in Xenopus Cycling Egg Extracts J Chun, ASS Chau, FG Maingat, SD Edmonds, HL Ostergaard, ... Cell Cycle 4 (1), 148-154, 2005 | 25 | 2005 |
Autosomal dominant tubulointerstitial kidney disease—uromodulin misclassified as focal segmental glomerulosclerosis or hereditary glomerular disease J Chun, M Wang, MS Wilkins, AU Knob, A Benjamin, L Bu, MR Pollak Kidney International Reports 5 (4), 519-529, 2020 | 21 | 2020 |
Attenuation of SARS-CoV-2 infection by losartan in human kidney organoids W Rahmani, H Chung, S Sinha, MP Bui-Marinos, R Arora, A Jaffer, ... IScience 25 (2), 2022 | 16 | 2022 |
FSGS-causing INF2 mutation impairs cleaved INF2 N-fragment functions in podocytes B Subramanian, J Chun, C Perez-Gill, P Yan, IE Stillman, HN Higgs, ... Journal of the American Society of Nephrology 31 (2), 374-391, 2020 | 16 | 2020 |
DGAT2 inhibition potentiates lipid droplet formation to reduce cytotoxicity in APOL1 kidney risk variants J Chun, CV Riella, H Chung, SS Shah, M Wang, JM Magraner, GT Ribas, ... Journal of the American Society of Nephrology 33 (5), 889-907, 2022 | 15 | 2022 |
AIM2 suppresses inflammation and epithelial cell proliferation during glomerulonephritis H Chung, T Komada, A Lau, M Chappellaz, JM Platnich, HD de Koning, ... The Journal of Immunology 207 (11), 2799-2812, 2021 | 12 | 2021 |