| 3D cell culture systems modeling tumor growth determinants in cancer target discovery CR Thoma, M Zimmermann, I Agarkova, JM Kelm, W Krek Advanced drug delivery reviews 69, 29-41, 2014 | 573 | 2014 |
| Global identification of modular cullin-RING ligase substrates MJ Emanuele, AEH Elia, Q Xu, CR Thoma, L Izhar, Y Leng, A Guo, ... Cell 147 (2), 459-474, 2011 | 460 | 2011 |
| pVHL and GSK3β are components of a primary cilium-maintenance signalling network CR Thoma, IJ Frew, CR Hoerner, M Montani, H Moch, W Krek Nature cell biology 9 (5), 588-595, 2007 | 277 | 2007 |
| Analysis of microtubule dynamic instability using a plus-end growth marker A Matov, K Applegate, P Kumar, C Thoma, W Krek, G Danuser, ... Nature methods 7 (9), 761-768, 2010 | 270 | 2010 |
| VHL loss causes spindle misorientation and chromosome instability CR Thoma, A Toso, KL Gutbrodt, SP Reggi, IJ Frew, P Schraml, ... Nature cell biology 11 (8), 994-1001, 2009 | 192 | 2009 |
| pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation IJ Frew, CR Thoma, S Georgiev, A Minola, M Hitz, M Montani, H Moch, ... The EMBO journal 27 (12), 1747-1757, 2008 | 178 | 2008 |
| Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia P Schraml, IJ Frew, CR Thoma, G Boysen, K Struckmann, W Krek, H Moch Modern Pathology 22 (1), 31-36, 2009 | 136 | 2009 |
| Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3 A Hergovich, J Lisztwan, CR Thoma, C Wirbelauer, RE Barry, W Krek Molecular and cellular biology 26 (15), 5784-5796, 2006 | 98 | 2006 |
| Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability CR Thoma, A Matov, KL Gutbrodt, CR Hoerner, Z Smole, W Krek, ... Journal of Cell Biology 190 (6), 991-1003, 2010 | 71 | 2010 |
| The VHL tumor suppressor: riding tandem with GSK3β in primary cilium maintenance CR Thoma, IJ Frew, W Krek Cell cycle 6 (15), 1809-1813, 2007 | 67 | 2007 |
| O mannosylation of α-dystroglycan is essential for lymphocytic choriomeningitis virus receptor function M Imperiali, C Thoma, E Pavoni, A Brancaccio, N Callewaert, A Oxenius Journal of virology 79 (22), 14297-14308, 2005 | 67 | 2005 |
| A high-throughput–compatible 3D microtissue co-culture system for phenotypic RNAi screening applications CR Thoma, S Stroebel, N Rösch, B Calpe, W Krek, JM Kelm Journal of biomolecular screening 18 (10), 1330-1337, 2013 | 62 | 2013 |
| Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma G Boysen, D Bausch-Fluck, CR Thoma, AM Nowicka, DP Stiehl, I Cima, ... Neoplasia 14 (6), 535-IN17, 2012 | 57 | 2012 |
| miR-28-5p Promotes Chromosomal Instability in VHL-Associated Cancers by Inhibiting Mad2 Translation MP Hell, CR Thoma, N Fankhauser, Y Christinat, TC Weber, W Krek Cancer research 74 (9), 2432-2443, 2014 | 55 | 2014 |
| DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic-and acquired-degrader resistance M Schröder, M Renatus, X Liang, F Meili, T Zoller, S Ferrand, F Gauter, ... Nature communications 15 (1), 275, 2024 | 32 | 2024 |
| Structure of the MRAS–SHOC2–PP1C phosphatase complex ZJ Hauseman, M Fodor, A Dhembi, J Viscomi, D Egli, M Bleu, S Katz, ... Nature 609 (7926), 416-423, 2022 | 32 | 2022 |
| BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma E Weisberg, B Chowdhury, C Meng, AE Case, W Ni, S Garg, M Sattler, ... Blood cancer journal 12 (7), 110, 2022 | 29 | 2022 |
| Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen L Schukur, T Zimmermann, O Niewoehner, G Kerr, S Gleim, ... Scientific Reports 10 (1), 20044, 2020 | 29 | 2020 |
| Tumor suppressor NF2/Merlin is a microtubule stabilizer Z Smole, CR Thoma, KT Applegate, M Duda, KL Gutbrodt, G Danuser, ... Cancer research 74 (1), 353-362, 2014 | 27 | 2014 |
| Discovery of new binders for DCAF1, an emerging ligase target in the targeted protein degradation field A Vulpetti, P Holzer, N Schmiedeberg, P Imbach-Weese, ... ACS Medicinal Chemistry Letters 14 (7), 949-954, 2023 | 18 | 2023 |
