| Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity T Sakuma, H Ochiai, T Kaneko, T Mashimo, D Tokumasu, Y Sakane, ... Scientific reports 3 (1), 3379, 2013 | 244 | 2013 |
| Efficient TALEN construction and evaluation methods for human cell and animal applications T Sakuma, S Hosoi, K Woltjen, K Suzuki, K Kashiwagi, H Wada, H Ochiai, ... Genes to Cells 18 (4), 315-326, 2013 | 239 | 2013 |
| Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases T Watanabe, H Ochiai, T Sakuma, HW Horch, N Hamaguchi, T Nakamura, ... Nature communications 3 (1), 1017, 2012 | 215 | 2012 |
| The microtubule-depolymerizing activity of a mitotic kinesin protein KIF2A drives primary cilia disassembly coupled with cell proliferation T Miyamoto, K Hosoba, H Ochiai, E Royba, H Izumi, T Sakuma, ... Cell reports 10 (5), 664-673, 2015 | 160 | 2015 |
| Single-molecule nanoscopy elucidates RNA polymerase II transcription at single genes in live cells J Li, A Dong, K Saydaminova, H Chang, G Wang, H Ochiai, T Yamamoto, ... Cell 178 (2), 491-506. e28, 2019 | 123 | 2019 |
| Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells H Ochiai, T Sugawara, T Sakuma, T Yamamoto Scientific reports 4 (1), 7125, 2014 | 112 | 2014 |
| Targeted mutagenesis in the sea urchin embryo using zinc‐finger nucleases H Ochiai, K Fujita, K Suzuki, M Nishikawa, T Shibata, N Sakamoto, ... Genes to cells 15 (8), 875-885, 2010 | 102 | 2010 |
| Simultaneous live imaging of the transcription and nuclear position of specific genes H Ochiai, T Sugawara, T Yamamoto Nucleic acids research 43 (19), e127-e127, 2015 | 92 | 2015 |
| High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos KT Suzuki, Y Isoyama, K Kashiwagi, T Sakuma, H Ochiai, N Sakamoto, ... Biology open 2 (5), 448-452, 2013 | 88 | 2013 |
| Single-gene imaging links genome topology, promoter–enhancer communication and transcription control J Li, A Hsu, Y Hua, G Wang, L Cheng, H Ochiai, T Yamamoto, ... Nature structural & molecular biology 27 (11), 1032-1040, 2020 | 78 | 2020 |
| Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells H Ochiai, T Hayashi, M Umeda, M Yoshimura, A Harada, Y Shimizu, ... Science Advances 6 (25), eaaz6699, 2020 | 66 | 2020 |
| TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome H Ochiai, T Miyamoto, A Kanai, K Hosoba, T Sakuma, Y Kudo, K Asami, ... Proceedings of the National Academy of Sciences 111 (4), 1461-1466, 2014 | 62 | 2014 |
| Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos H Ochiai, N Sakamoto, K Fujita, M Nishikawa, K Suzuki, S Matsuura, ... Proceedings of the National Academy of Sciences 109 (27), 10915-10920, 2012 | 48 | 2012 |
| Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc‐finger nucleases N Kawai, H Ochiai, T Sakuma, L Yamada, H Sawada, T Yamamoto, ... Development, growth & differentiation 54 (5), 535-545, 2012 | 44 | 2012 |
| Targeted disruption of exogenous EGFP gene in medaka using zinc‐finger nucleases S Ansai, H Ochiai, Y Kanie, Y Kamei, Y Gou, T Kitano, T Yamamoto, ... Development, growth & differentiation 54 (5), 546-556, 2012 | 42 | 2012 |
| Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome T Miyamoto, K Hosoba, T Itabashi, AH Iwane, SN Akutsu, H Ochiai, ... The EMBO journal 39 (12), e103499, 2020 | 37 | 2020 |
| PHi-C: deciphering Hi-C data into polymer dynamics S Shinkai, M Nakagawa, T Sugawara, Y Togashi, H Ochiai, R Nakato, ... NAR genomics and bioinformatics 2 (2), lqaa020, 2020 | 33 | 2020 |
| Single-base pair genome editing in human cells by using site-specific endonucleases H Ochiai International journal of molecular sciences 16 (9), 21128-21137, 2015 | 23 | 2015 |
| Role of dynamic nuclear deformation on genomic architecture reorganization S Seirin-Lee, F Osakada, J Takeda, S Tashiro, R Kobayashi, T Yamamoto, ... PLoS computational biology 15 (9), e1007289, 2019 | 21 | 2019 |
| Equarin is involved as an FGF signaling modulator in chick lens differentiation X Song, Y Sato, A Felemban, A Ito, M Hossain, H Ochiai, T Yamamoto, ... Developmental biology 368 (1), 109-117, 2012 | 21 | 2012 |
