Hiroshi Ochiai
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Efficient TALEN construction and evaluation methods for human cell and animal applications
T Sakuma, S Hosoi, K Woltjen, K Suzuki, K Kashiwagi, H Wada, H Ochiai, ...
Genes to Cells 18 (4), 315-326, 2013
Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity
T Sakuma, H Ochiai, T Kaneko, T Mashimo, D Tokumasu, Y Sakane, ...
Scientific reports 3 (1), 1-8, 2013
Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases
T Watanabe, H Ochiai, T Sakuma, HW Horch, N Hamaguchi, T Nakamura, ...
Nature communications 3 (1), 1-8, 2012
The microtubule-depolymerizing activity of a mitotic kinesin protein KIF2A drives primary cilia disassembly coupled with cell proliferation
T Miyamoto, K Hosoba, H Ochiai, E Royba, H Izumi, T Sakuma, ...
Cell reports 10 (5), 664-673, 2015
Targeted mutagenesis in the sea urchin embryo using zinc‐finger nucleases
H Ochiai, K Fujita, K Suzuki, M Nishikawa, T Shibata, N Sakamoto, ...
Genes to Cells 15 (8), 875-885, 2010
High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos
TS Ken-ichi, Y Isoyama, K Kashiwagi, T Sakuma, H Ochiai, N Sakamoto, ...
Biology open 2 (5), 448-452, 2013
Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells
H Ochiai, T Sugawara, T Sakuma, T Yamamoto
Scientific reports 4 (1), 1-9, 2014
Simultaneous live imaging of the transcription and nuclear position of specific genes
H Ochiai, T Sugawara, T Yamamoto
Nucleic acids research 43 (19), e127-e127, 2015
TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome
H Ochiai, T Miyamoto, A Kanai, K Hosoba, T Sakuma, Y Kudo, K Asami, ...
Proceedings of the National Academy of Sciences 111 (4), 1461-1466, 2014
Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos
H Ochiai, N Sakamoto, K Fujita, M Nishikawa, K Suzuki, S Matsuura, ...
Proceedings of the National Academy of Sciences 109 (27), 10915-10920, 2012
Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc‐finger nucleases
N Kawai, H Ochiai, T Sakuma, L Yamada, H Sawada, T Yamamoto, ...
Development, growth & differentiation 54 (5), 535-545, 2012
Targeted disruption of exogenous EGFP gene in medaka using zinc‐finger nucleases
S Ansai, H Ochiai, Y Kanie, Y Kamei, Y Gou, T Kitano, T Yamamoto, ...
Development, growth & differentiation 54 (5), 546-556, 2012
Single-molecule nanoscopy elucidates RNA polymerase II transcription at single genes in live cells
J Li, A Dong, K Saydaminova, H Chang, G Wang, H Ochiai, T Yamamoto, ...
Cell 178 (2), 491-506. e28, 2019
Analysis of cis-regulatory elements controlling spatio-temporal expression of T-brain gene in sea urchin, Hemicentrotus pulcherrimus
H Ochiai, N Sakamoto, A Momiyama, K Akasaka, T Yamamoto
Mechanisms of development 125 (1-2), 2-17, 2008
Equarin is involved as an FGF signaling modulator in chick lens differentiation
X Song, Y Sato, A Felemban, A Ito, M Hossain, H Ochiai, T Yamamoto, ...
Developmental biology 368 (1), 109-117, 2012
Role of the nanos homolog during sea urchin development
T Fujii, N Sakamoto, H Ochiai, K Fujita, Y Okamitsu, N Sumiyoshi, ...
Developmental dynamics: an official publication of the American Association …, 2009
Single-base pair genome editing in human cells by using site-specific endonucleases
H Ochiai
International journal of molecular sciences 16 (9), 21128-21137, 2015
The Ars insulator facilitates I‐SceI meganuclease‐mediated transgenesis in the sea urchin embryo
H Ochiai, N Sakamoto, K Suzuki, K Akasaka, T Yamamoto
Developmental Dynamics: An Official Publication of the American Association …, 2008
Genome editing using zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)
H Ochiai, T Yamamoto
Targeted Genome Editing Using Site-Specific Nucleases, 3-24, 2015
Analysis of individual differences in radiosensitivity using genome editing
S Matsuura, E Royba, SN Akutsu, H Yanagihara, H Ochiai, Y Kudo, ...
Annals of the ICRP 45 (1_suppl), 290-296, 2016
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Articles 1–20