| Valence and patterning of aromatic residues determine the phase behavior of prion-like domains EW Martin, AS Holehouse, I Peran, M Farag, JJ Incicco, A Bremer, ... Science 367 (6478), 694-699, 2020 | 659 | 2020 |
| NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor CRR Grace, MH Perrin, MR DiGruccio, CL Miller, JE Rivier, WW Vale, ... Proceedings of the National Academy of Sciences 101 (35), 12836-12841, 2004 | 249 | 2004 |
| BID-induced structural changes in BAK promote apoptosis T Moldoveanu, CR Grace, F Llambi, A Nourse, P Fitzgerald, K Gehring, ... Nature structural & molecular biology 20 (5), 589-597, 2013 | 236 | 2013 |
| Sequence determinants of the conformational properties of an intrinsically disordered protein prior to and upon multisite phosphorylation EW Martin, AS Holehouse, CR Grace, A Hughes, RV Pappu, T Mittag Journal of the American Chemical Society 138 (47), 15323-15335, 2016 | 228 | 2016 |
| Sequential engagement of distinct MLKL phosphatidylinositol-binding sites executes necroptosis G Quarato, CS Guy, CR Grace, F Llambi, A Nourse, DA Rodriguez, ... Molecular cell 61 (4), 589-601, 2016 | 216 | 2016 |
| PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis AV Follis, JE Chipuk, JC Fisher, MK Yun, CR Grace, A Nourse, K Baran, ... Nature chemical biology 9 (3), 163-168, 2013 | 190 | 2013 |
| Structural polymorphism in the N-terminal oligomerization domain of NPM1 DM Mitrea, CR Grace, M Buljan, MK Yun, NJ Pytel, J Satumba, A Nourse, ... Proceedings of the National Academy of Sciences 111 (12), 4466-4471, 2014 | 173 | 2014 |
| Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand CRR Grace, MH Perrin, J Gulyas, MR DiGruccio, JP Cantle, JE Rivier, ... Proceedings of the National Academy of Sciences 104 (12), 4858-4863, 2007 | 160 | 2007 |
| Dual RING E3 architectures regulate multiubiquitination and ubiquitin chain elongation by APC/C NG Brown, R VanderLinden, ER Watson, F Weissmann, A Ordureau, ... Cell 165 (6), 1440-1453, 2016 | 146 | 2016 |
| MLKL requires the inositol phosphate code to execute necroptosis CM Dovey, J Diep, BP Clarke, AT Hale, DE McNamara, H Guo, NW Brown, ... Molecular cell 70 (5), 936-948. e7, 2018 | 137 | 2018 |
| NMR techniques for very large proteins and RNAs in solution AG Tzakos, CRR Grace, PJ Lukavsky, R Riek Annu. Rev. Biophys. Biomol. Struct. 35, 319-342, 2006 | 130 | 2006 |
| A dual E3 mechanism for Rub1 ligation to Cdc53 DC Scott, JK Monda, CRR Grace, DM Duda, RW Kriwacki, T Kurz, ... Molecular cell 39 (5), 784-796, 2010 | 122 | 2010 |
| Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly NG Brown, ER Watson, F Weissmann, MA Jarvis, R VanderLinden, ... Molecular cell 56 (2), 246-260, 2014 | 113 | 2014 |
| Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown JJ Frye, NG Brown, G Petzold, ER Watson, CRR Grace, A Nourse, ... Nature structural & molecular biology 20 (7), 827-835, 2013 | 104 | 2013 |
| RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex NG Brown, R VanderLinden, ER Watson, R Qiao, CRR Grace, ... Proceedings of the National Academy of Sciences 112 (17), 5272-5279, 2015 | 92 | 2015 |
| Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling R Rana, CE Carroll, HJ Lee, J Bao, S Marada, CRR Grace, CD Guibao, ... Nature communications 4 (1), 2965, 2013 | 87 | 2013 |
| Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation EW Martin, FE Thomasen, NM Milkovic, MJ Cuneo, CR Grace, A Nourse, ... Nucleic acids research 49 (5), 2931-2945, 2021 | 82 | 2021 |
| MicroRNAs form triplexes with double stranded DNA at sequence-specific binding sites; a eukaryotic mechanism via which microRNAs could directly alter gene expression SW Paugh, DR Coss, J Bao, LT Laudermilk, CR Grace, AM Ferreira, ... PLoS computational biology 12 (2), e1004744, 2016 | 76 | 2016 |
| Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis LB Epling, CR Grace, BR Lowe, JF Partridge, EJ Enemark Journal of molecular biology 427 (9), 1779-1796, 2015 | 72 | 2015 |
| Common and divergent structural features of a series of corticotropin releasing factor-related peptides CRR Grace, MH Perrin, JP Cantle, WW Vale, JE Rivier, R Riek Journal of the American Chemical Society 129 (51), 16102-16114, 2007 | 67 | 2007 |
Richard KriwackiSt. Jude Children's Research HospitalVerified email at stjude.org
