James R Staley
James R Staley
Computational Genetics Lead, UCB
Verified email at
Cited by
Cited by
Genomic atlas of the human plasma proteome
BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley, J Blackshaw, ...
Nature 558 (7708), 73-79, 2018
PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations
MA Kamat, JA Blackshaw, R Young, P Surendran, S Burgess, J Danesh, ...
Bioinformatics 35 (22), 4851-4853, 2019
The allelic landscape of human blood cell trait variation and links to common complex disease
WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ...
Cell 167 (5), 1415-1429. e19, 2016
PhenoScanner: a database of human genotype–phenotype associations
JR Staley, J Blackshaw, MA Kamat, S Ellis, P Surendran, BB Sun, ...
Bioinformatics 32 (20), 3207-3209, 2016
Association of LPA variants with risk of coronary disease and the implications for lipoprotein (a)-lowering therapies: a Mendelian randomization analysis
S Burgess, BA Ference, JR Staley, DF Freitag, AM Mason, SF Nielsen, ...
JAMA cardiology 3 (7), 619-627, 2018
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ...
Nature genetics 52 (10), 1122-1131, 2020
A robust and efficient method for Mendelian randomization with hundreds of genetic variants
S Burgess, CN Foley, E Allara, JR Staley, JMM Howson
Nature communications 11 (1), 376, 2020
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
P Surendran, F Drenos, R Young, H Warren, JP Cook, AK Manning, ...
Nature genetics 48 (10), 1151-1161, 2016
A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits
CN Foley, JR Staley, PG Breen, BB Sun, PDW Kirk, S Burgess, ...
Nature communications 12 (1), 764, 2021
Semiparametric methods for estimation of a nonlinear exposure‐outcome relationship using instrumental variables with application to Mendelian randomization
JR Staley, S Burgess
Genetic epidemiology 41 (4), 341-352, 2017
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses
YQ Sun, S Burgess, JR Staley, AM Wood, S Bell, SK Kaptoge, Q Guo, ...
bmj 364, 2019
The EWAS Catalog: a database of epigenome-wide association studies
T Battram, P Yousefi, G Crawford, C Prince, MS Babaei, G Sharp, ...
Wellcome open research 7, 2022
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ...
Nature genetics 52 (12), 1314-1332, 2020
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis
Interleukin 1 Genetics Consortium
The Lancet Diabetes & Endocrinology 3 (4), 243-253, 2015
Associations of blood pressure in pregnancy with offspring blood pressure trajectories during childhood and adolescence: findings from a prospective study
JR Staley, J Bradley, RJ Silverwood, LD Howe, K Tilling, DA Lawlor, ...
Journal of the American Heart Association 4 (5), e001422, 2015
MendelianRandomization v0. 5.0: updates to an R package for performing Mendelian randomization analyses using summarized data
JR Broadbent, CN Foley, AJ Grant, AM Mason, JR Staley, S Burgess
Wellcome open research 5, 2020
A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design
JR Staley, E Jones, S Kaptoge, AS Butterworth, MJ Sweeting, AM Wood, ...
European Journal of Human Genetics 25 (7), 854-862, 2017
Dmrff: Identifying differentially methylated regions efficiently with power and control
M Suderman, JR Staley, R French, R Arathimos, A Simpkin, K Tilling
BioRxiv, 508556, 2018
Coding and regulatory variants are associated with serum protein levels and disease
V Emilsson, V Gudmundsdottir, A Gudjonsson, T Jonmundsson, ...
Nature Communications 13 (1), 481, 2022
The effect of attention deficit/hyperactivity disorder on physical health outcomes: a 2-sample Mendelian randomization study
B Leppert, L Riglin, RE Wootton, C Dardani, A Thapar, JR Staley, K Tilling, ...
American journal of epidemiology 190 (6), 1047-1055, 2021
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