| Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling O Kauko, TD Laajala, M Jumppanen, P Hintsanen, V Suni, P Haapaniemi, ... Scientific reports 5 (1), 13099, 2015 | 61 | 2015 |
| Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1 O Kauko, SY Imanishi, E Kulesskiy, L Yetukuri, TD Laajala, M Sharma, ... Journal of Biological Chemistry 295 (13), 4194-4211, 2020 | 58 | 2020 |
| PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells A Kaur, OV Denisova, X Qiao, M Jumppanen, E Peuhu, SU Ahmed, ... Cancer research 76 (23), 7001-7011, 2016 | 56 | 2016 |
| Optimized design and analysis of preclinical intervention studies in vivo TD Laajala, M Jumppanen, R Huhtaniemi, V Fey, A Kaur, M Knuuttila, ... Scientific reports 6 (1), 1-13, 2016 | 45 | 2016 |
| Biosynthesis of the bis-prenylated alkaloids muscoride A and B A Mattila, RM Andsten, M Jumppanen, M Assante, J Jokela, M Wahlsten, ... ACS Chemical Biology 14 (12), 2683-2690, 2019 | 32 | 2019 |
| Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds ST Karhu, MJ Välimäki, M Jumppanen, SM Kinnunen, L Pohjolainen, ... Archives of Toxicology 92, 2897-2911, 2018 | 30 | 2018 |
| Synthesis, identification, and structure–activity relationship analysis of GATA4 and NKX2-5 protein–protein interaction modulators M Jumppanen, SM Kinnunen, MJ Välimäki, V Talman, S Auno, ... Journal of Medicinal Chemistry 62 (17), 8284-8310, 2019 | 24 | 2019 |
| Rules for PP2A-controlled phosphosignalling and drug responses O Kauko, SY Imanishi, E Kulesskiy, TD Laajala, L Yetukuri, A Laine, ... BioRxiv, 271841, 2018 | 14 | 2018 |
| Adenosine analogs bearing phosphate isosteres as human MDO1 ligands Y Zhang, M Jumppanen, MM Maksimainen, S Auno, Z Awol, L Ghemtio, ... Bioorganic & Medicinal Chemistry 26 (8), 1588-1597, 2018 | 10 | 2018 |
| PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells OV Denisova, J Merisaari, R Huhtaniemi, X Qiao, L Yetukuri, ... Molecular oncology 17 (9), 1803-1820, 2023 | 3 | 2023 |
| Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells OV Denisova, J Merisaari, A Kaur, L Yetukuri, M Jumppanen, ... Scientific Reports 12 (1), 13796, 2022 | 3 | 2022 |
| Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models OV Denisova, J Merisaari, R Huhtaniemi, X Qiao, A Kaur, L Yetukuri, ... bioRxiv, 2022.05. 31.494146, 2022 | 1 | 2022 |
| Affinity chromatography reveals direct binding of the GATA4–NKX2-5 interaction inhibitor (3i-1000) with GATA4 M Jumppanen, SM Kinnunen, M Zore, MJ Välimäki, V Talman, ... Scientific Reports 14 (1), 8938, 2024 | | 2024 |
| 5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions HT Patsi, TP Kilpeläinen, M Jumppanen, J Uhari-Vaananen, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
| Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compound L Pohjolainen, SM Kinnunen, S Auno, A Kiriazis, S Pohjavaara, ... Stem Cell Research & Therapy 15 (1), 5, 2024 | | 2024 |
| Triplet kinase-phosphatase targeting to overcome kinase inhibitor tolerance in brain tumor cells OV Denisova, J Merisaari, R Huhtaniemi, X Qiao, L Yetukuri, ... bioRxiv, 2022.01. 20.477108, 2022 | | 2022 |
| Synthesis and SAR Analysis of GATA4-NKX2-5 Interaction Inhibitors with Antihypertrophic Activity M Jumppanen Helsingin yliopisto, 2020 | | 2020 |
| Regioselective Prenylation of Peptide Termini during the Biosynthesis of the Natural Product Muscoride A Mattila, RM Andsten, M Jumppanen, M Assante, J Jokela, M Wahlsten, ... Marine Drugs 18 (1), 40, 2020 | | 2020 |
| Structure-activity relationship-guided synthesis and identification of the GATA4 and NKX2-5 protein-protein interaction modulators M Jumppanen, S Kinnunen, M Valimaki, S Auno, GBA Gennas, H Xhaard, ... Abstracts of papers of the American Chemical Society 257, 2019 | | 2019 |
| Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted small-molecule compounds T Karhu, M Valimaki, M Jumppanen, L Pohjolainen, R Leigh, G Foldes, ... Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018 | | 2018 |
