|The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme|
P Krishnamurthy, DD Ross, T Nakanishi, K Bailey-Dell, S Zhou, ...
Journal of Biological Chemistry 279 (23), 24218-24225, 2004
|SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria|
Y Chino, Y Samukawa, S Sakai, Y Nakai, J Yamaguchi, T Nakanishi, ...
Biopharmaceutics & drug disposition 35 (7), 391-404, 2014
|Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression|
T Nakanishi, DD Ross
Chinese journal of cancer 31 (2), 73, 2012
|Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir|
PV Balimane, I Tamai, A Guo, T Nakanishi, H Kitada, FH Leibach, A Tsuji, ...
Biochemical and biophysical research communications 250 (2), 246-251, 1998
|Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A|
M Sugawara, T Nakanishi, YJ Fei, W Huang, ME Ganapathy, FH Leibach, ...
Journal of Biological Chemistry 275 (22), 16473-16477, 2000
|Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2|
A Hosomi, T Nakanishi, T Fujita, I Tamai
PloS one 7 (2), e30456, 2012
|The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells|
Y Xie, K Xu, DE Linn, X Yang, Z Guo, H Shimelis, T Nakanishi, DD Ross, ...
Journal of Biological Chemistry 283 (6), 3349-3356, 2008
|Rapid Report: Na+‐and Cl−‐coupled active transport of carnitine by the amino acid transporter ATB0,+ from mouse colon expressed in HRPE cells and Xenopus oocytes|
T Nakanishi, T Hatanaka, W Huang, PD Prasad, FH Leibach, ...
The Journal of physiology 532 (2), 297-304, 2001
|Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL–expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression|
T Nakanishi, K Shiozawa, BA Hassel, DD Ross
Blood 108 (2), 678-684, 2006
|Improvement of L‐dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1|
I Tamai, T Nakanishi, H Nakahara, Y Sai, V Ganapathy, FH Leibach, ...
Journal of pharmaceutical sciences 87 (12), 1542-1546, 1998
|Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle|
M Sugawara, T Nakanishi, YJ Fei, RG Martindale, ME Ganapathy, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1509 (1-2), 7-13, 2000
|Putative transport mechanism and intracellular fate of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid in human prostate cancer|
H Okudaira, N Shikano, R Nishii, T Miyagi, M Yoshimoto, M Kobayashi, ...
Journal of Nuclear Medicine 52 (5), 822-829, 2011
|Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons|
NN Jong, T Nakanishi, JJ Liu, I Tamai, MJ McKeage
Journal of Pharmacology and Experimental Therapeutics 338 (2), 537-547, 2011
|Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat|
Y Shirasaka, E Kuraoka, H Spahn-Langguth, T Nakanishi, P Langguth, ...
Journal of Pharmacology and Experimental Therapeutics 332 (1), 181-189, 2010
|Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions|
Y Shirasaka, M Shichiri, T Mori, T Nakanishi, I Tamai
Journal of pharmaceutical sciences 102 (1), 280-288, 2013
|Genetic polymorphisms of OATP transporters and their impact on intestinal absorption and hepatic disposition of drugs|
T Nakanishi, I Tamai
Drug metabolism and pharmacokinetics 27 (1), 106-121, 2012
|Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy|
T Nakanishi, I Tamai
Journal of pharmaceutical sciences 100 (9), 3731-3750, 2011
|Involvement of OCTN1 (SLC22A4) in pH-Dependent Transport of Organic Cations|
I Tamai, T Nakanishi, D Kobayashi, K China, Y Kosugi, J Nezu, Y Sai, ...
Molecular Pharmaceutics 1 (1), 57-66, 2004
|Cloning and functional characterization of a new subtype of the amino acid transport system N|
T Nakanishi, R Kekuda, YJ Fei, T Hatanaka, M Sugawara, RG Martindale, ...
American Journal of Physiology-Cell Physiology 281 (6), C1757-C1768, 2001
|Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N|
T Nakanishi, M Sugawara, W Huang, RG Martindale, FH Leibach, ...
Biochemical and biophysical research communications 281 (5), 1343-1348, 2001