The NOX toolbox: validating the role of NADPH oxidases in physiology and disease S Altenhöfer, PWM Kleikers, KA Radermacher, P Scheurer, ... Cellular and Molecular Life Sciences 69, 2327-2343, 2012 | 448 | 2012 |
NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury PWM Kleikers, K Wingler, JJR Hermans, I Diebold, S Altenhöfer, ... Journal of molecular medicine 90, 1391-1406, 2012 | 197 | 2012 |
Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress KA Radermacher, K Wingler, F Langhauser, S Altenhöfer, P Kleikers, ... Antioxidants & redox signaling 18 (12), 1418-1427, 2013 | 179 | 2013 |
NOX1, 2, 4, 5: counting out oxidative stress K Wingler, JJR Hermans, P Schiffers, AL Moens, M Paul, H Schmidt British journal of pharmacology 164 (3), 866-883, 2011 | 132 | 2011 |
Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics JJR Hermans, HHW Thijssen British journal of pharmacology 110 (1), 482-490, 2012 | 109 | 2012 |
Overexpression of 17β-hydroxysteroid dehydrogenase type 1 increases the exposure of endometrial cancer to 17β-estradiol KMC Cornel, RFPM Kruitwagen, B Delvoux, L Visconti, KK Van de Vijver, ... The Journal of Clinical Endocrinology & Metabolism 97 (4), E591-E601, 2012 | 85 | 2012 |
Inhibition of type 1 17β-hydroxysteroid dehydrogenase impairs the synthesis of 17β-estradiol in endometriosis lesions B Delvoux, T D'Hooghe, C Kyama, P Koskimies, RJJ Hermans, ... The Journal of Clinical Endocrinology & Metabolism 99 (1), 276-284, 2014 | 69 | 2014 |
Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics L Roumen, MPA Sanders, K Pieterse, PAJ Hilbers, R Plate, E Custers, ... Journal of computer-aided molecular design 21, 455-471, 2007 | 69 | 2007 |
VAS2870 is a pan-NADPH oxidase inhibitor K Wingler, SA Altenhoefer, PWM Kleikers, KA Radermacher, ... Cellular and Molecular Life Sciences 69, 3159-3160, 2012 | 67 | 2012 |
Transient AT1 receptor-inhibition in prehypertensive spontaneously hypertensive rats results in maintained cardiac protection until advanced age M Baumann, BJA Janssen, JJR Hermans, C Peutz-Kootstra, O Witzke, ... Journal of hypertension 25 (1), 207-215, 2007 | 67 | 2007 |
The in vitro ketone reduction of warfarin and analogues: substrate stereoselectivity, product stereoselectivity and species differences JJR Hermans, HHW Thijssen Biochemical pharmacology 38 (19), 3365-3370, 1989 | 64 | 1989 |
The 1027th target candidate in stroke: Will NADPH oxidase hold up? KA Radermacher, K Wingler, P Kleikers, S Altenhöfer, J JR Hermans, ... Experimental & translational stroke medicine 4, 1-11, 2012 | 59 | 2012 |
Synthesis, Biological Evaluation, and Molecular Modeling of 1-Benzyl-1H-imidazoles as Selective Inhibitors of Aldosterone Synthase (CYP11B2) L Roumen, JW Peeters, JMA Emmen, IPE Beugels, EMG Custers, ... Journal of medicinal chemistry 53 (4), 1712-1725, 2010 | 52 | 2010 |
Role of the Rhoa/Rho kinase system in flow-related remodeling of rat mesenteric small arteries in vivo JPM Wesselman, R Kuijs, JJ Hermans, GMJ Janssen, GE Fazzi, ... Journal of vascular research 41 (3), 277-290, 2004 | 52 | 2004 |
Diurnal rhythms of serum and plasma cytokine profiles in healthy elderly individuals assessed using membrane based multiplexed immunoassay R Altara, M Manca, KCM Hermans, EP Daskalopoulos, HPBL Rocca, ... Journal of translational medicine 13, 1-8, 2015 | 48 | 2015 |
Determination of the class III antiarrhythmic drugs dronedarone and amiodarone, and their principal metabolites in plasma and myocardium by high-performance liquid … RW Bolderman, JJR Hermans, JG Maessen Journal of Chromatography B 877 (18-19), 1727-1731, 2009 | 44 | 2009 |
Pharmacokinetic advantage of intrapericardially applied substances in the rat JJR Hermans, H van Essen, HAJ Struijker-Boudier, RM Johnson, ... Journal of Pharmacology and Experimental Therapeutics 301 (2), 672-678, 2002 | 40 | 2002 |
Intrapericardial delivery enhances cardiac effects of sotalol and atenolol TJ van Brakel, JJR Hermans, BJ Janssen, H van Essen, N Botterhuis, ... Journal of cardiovascular pharmacology 44 (1), 50-56, 2004 | 33 | 2004 |
Stereoselective acetonyl side chain reduction of warfarin and analogs. Partial characterization of two cytosolic carbonyl reductases. JJ Hermans, HH Thijssen Drug metabolism and disposition 20 (2), 268-274, 1992 | 33 | 1992 |
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of spironolactone and losartan regarding long-term blood pressure and target organ damage M Baumann, JJR Hermans, BJA Janssen, C Peutz-Kootstra, O Witzke, ... Journal of hypertension 25 (12), 2504-2511, 2007 | 28 | 2007 |