Tracing entire operation cycles of molecular motor hepatitis C virus helicase in structurally resolved dynamical simulations H Flechsig, AS Mikhailov Proceedings of the National Academy of Sciences 107 (49), 20875-20880, 2010 | 55 | 2010 |
BioAFMviewer: An interactive interface for simulated AFM scanning of biomolecular structures and dynamics R Amyot, H Flechsig PLoS computational biology 16 (11), e1008444, 2020 | 54 | 2020 |
Design of elastic networks with evolutionary optimized long-range communication as mechanical models of allosteric proteins H Flechsig Biophysical journal 113 (3), 558-571, 2017 | 51 | 2017 |
Coarse-grained protein dynamics studies using elastic network models Y Togashi, H Flechsig International journal of molecular sciences 19 (12), 3899, 2018 | 36 | 2018 |
Simple mechanics of protein machines H Flechsig, AS Mikhailov Journal of the Royal Society Interface 16 (155), 20190244, 2019 | 35 | 2019 |
An ultra-wide scanner for large-area high-speed atomic force microscopy with megapixel resolution A Marchesi, K Umeda, T Komekawa, T Matsubara, H Flechsig, T Ando, ... Scientific Reports 11 (1), 13003, 2021 | 27 | 2021 |
Simulation atomic force microscopy for atomic reconstruction of biomolecular structures from resolution-limited experimental images R Amyot, A Marchesi, CM Franz, I Casuso, H Flechsig PLoS computational biology 18 (3), e1009970, 2022 | 26 | 2022 |
Allosteric communication in molecular machines via information exchange: what can be learned from dynamical modeling D Loutchko, H Flechsig Biophysical reviews 12 (2), 443-452, 2020 | 23 | 2020 |
In silico investigation of conformational motions in superfamily 2 helicase proteins H Flechsig, D Popp, AS Mikhailov PLoS One 6 (7), e21809, 2011 | 21 | 2011 |
Designed elastic networks: Models of complex protein machinery H Flechsig, Y Togashi International journal of molecular sciences 19 (10), 3152, 2018 | 13 | 2018 |
Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy N Tochio, K Umehara, J Uewaki, H Flechsig, M Kondo, T Dewa, ... Scientific reports 6 (1), 37887, 2016 | 12 | 2016 |
Novel DNA aptamer for CYP24A1 inhibition with enhanced antiproliferative activity in cancer cells M Biyani, K Yasuda, Y Isogai, Y Okamoto, W Weilin, N Kodera, H Flechsig, ... ACS Applied Materials & Interfaces 14 (16), 18064-18078, 2022 | 11 | 2022 |
TALEs from a Spring – Superelasticity of Tal Effector Protein Structures H Flechsig PLOS ONE 9 (10), e109919, 2014 | 11 | 2014 |
Nucleotide-induced conformational dynamics in ABC transporters from structure-based coarse grained modeling H Flechsig Frontiers in Physics 4, 3, 2016 | 10 | 2016 |
Protein dynamics by the combination of high-speed AFM and computational modeling H Flechsig, T Ando Current Opinion in Structural Biology 80, 102591, 2023 | 9 | 2023 |
Deciphering intrinsic inter-subunit couplings that lead to sequential hydrolysis of F1-ATPase ring L Dai, H Flechsig, J Yu Biophysical journal 113 (7), 1440-1453, 2017 | 9 | 2017 |
Towards synthetic molecular motors: a model elastic-network study A Sarkar, H Flechsig, AS Mikhailov New Journal of Physics 18 (4), 043006, 2016 | 9 | 2016 |
Computational biology approach to uncover hepatitis C virus helicase operation H Flechsig World journal of gastroenterology: WJG 20 (13), 3401, 2014 | 7 | 2014 |
Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy S Tsujioka, A Sumino, Y Nagasawa, T Sumikama, H Flechsig, L Puppulin, ... Science Advances 9 (26), eadh1069, 2023 | 5 | 2023 |
BioAFMviewer software for simulation atomic force microscopy of molecular structures and conformational dynamics R Amyot, N Kodera, H Flechsig Journal of Structural Biology: X 7, 100086, 2023 | 4 | 2023 |