| The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome PJ Bosma, JR Chowdhury, C Bakker, S Gantla, A de Boer, BA Oostra, ... New England Journal of Medicine 333 (18), 1171-1175, 1995 | 1840 | 1995 |
| Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene CC Paulusma, PJ Bosma, GJR Zaman, CTM Bakker, M Otter, GL Scheffer, ... Science 271 (5252), 1126-1128, 1996 | 1026 | 1996 |
| Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis JML De Vree, E Jacquemin, E Sturm, D Cresteil, PJ Bosma, J Aten, ... Proceedings of the National Academy of Sciences 95 (1), 282-287, 1998 | 937 | 1998 |
| A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome CC Paulusma, M Kool, PJ Bosma, GL Scheffer, F ter Borg, RJ Scheper, ... Hepatology 25 (6), 1539-1542, 1997 | 701 | 1997 |
| The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood E Jacquemin, O Bernard, M Hadchouel, D Cresteil, JML De Vree, M Paul, ... Gastroenterology 120 (6), 1448-1458, 2001 | 610 | 2001 |
| Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man. PJ Bosma, J Seppen, B Goldhoorn, C Bakker, RPO Elferink, ... Journal of Biological Chemistry 269 (27), 17960-17964, 1994 | 542 | 1994 |
| Inherited disorders of bilirubin metabolism PJ Bosma Journal of hepatology 38 (1), 107-117, 2003 | 383 | 2003 |
| Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus CJ Buskens, BP Van Rees, A Sivula, JB Reitsma, C Haglund, PJ Bosma, ... Gastroenterology 122 (7), 1800-1807, 2002 | 336 | 2002 |
| Molecular mechanisms of initiation of fibrinolysis by fibrin L Medved, W Nieuwenhuizen Thrombosis and haemostasis 89 (03), 409-419, 2003 | 309 | 2003 |
| Plasminogen activator inhibitor 1: biosynthesis and mRNA level are increased by insulin in cultured human hepatocytes T Kooistra, PJ Bosma, HAM Töns, AP Van Den Berg, P Meyer, ... Thrombosis and haemostasis 62 (06), 723-728, 1989 | 262 | 1989 |
| Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis JML De Vree, R Ottenhoff, PJ Bosma, AJ Smith, J Aten, RPJO Elferink Gastroenterology 119 (6), 1720-1730, 2000 | 231 | 2000 |
| Sequence of exons and the flanking regions of human bilirubin‐UDP‐glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler‐Najjar … PJ Bosma, NR Chowdhury, BG Goldhoorn, MH Hofker, RPJO Elferink, ... Hepatology 15 (5), 941-947, 1992 | 230 | 1992 |
| Human plasminogen activator inhibitor-1 gene. Promoter and structural gene nucleotide sequences. PJ Bosma, EA van den Berg, T Kooistra, DR Siemieniak, JL Slightom Journal of Biological Chemistry 263 (19), 9129-9141, 1988 | 223 | 1988 |
| Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase. J Seppen, PJ Bosma, BG Goldhoorn, CT Bakker, JR Chowdhury, ... The Journal of clinical investigation 94 (6), 2385-2391, 1994 | 189 | 1994 |
| Transcriptional profiling reveals novel markers of liver fibrogenesis: gremlin and insulin-like growth factor-binding proteins W Boers, S Aarrass, C Linthorst, M Pinzani, RO Elferink, P Bosma Journal of Biological Chemistry 281 (24), 16289-16295, 2006 | 178 | 2006 |
| Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver CC Paulusma, MJ Kothe, CT Bakker, PJ Bosma, I van Bokhoven, ... Hepatology 31 (3), 684-693, 2000 | 166 | 2000 |
| Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors JG Wesseling, PJ Bosma, V Krasnykh, EA Kashentseva, JL Blackwell, ... Gene Therapy 8 (13), 969-976, 2001 | 140 | 2001 |
| Mechanisms of inherited deficiencies of multiple UDP‐glucuronosyltransferase isoforms in two patients with Crigler‐Najjar syndrome, type I PJ Bosma, JR Chowdhury, TJ Huang, P Lahiri, RPJO Elferink, ... The FASEB journal 6 (10), 2859-2863, 1992 | 136 | 1992 |
| A mutation in bilirubin uridine 5′-diphosphate-glucuronosyltransferase isoform 1 causing Crigler-Najjar syndrome type II PJ Bosma, B Goldhoorn, RPJO Elferink, M Sinaasappel, BA Oostra, ... Gastroenterology 105 (1), 216-220, 1993 | 120 | 1993 |
| Towards liver-directed gene therapy for Crigler-Najjar syndrome PS Montenegro Miranda, PJ Bosma Current Gene Therapy 9 (2), 72-82, 2009 | 96 | 2009 |
