| HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease) C Klein, M Grudzien, G Appaswamy, M Germeshausen, I Sandrock, ... Nature genetics 39 (1), 86-92, 2007 | 591 | 2007 |
| Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts A Kode, JS Manavalan, I Mosialou, G Bhagat, CV Rathinam, N Luo, ... Nature 506 (7487), 240-244, 2014 | 590 | 2014 |
| Leptin and insulin act on POMC neurons to promote the browning of white fat GT Dodd, S Decherf, K Loh, SE Simonds, F Wiede, E Balland, TL Merry, ... Cell 160 (1), 88-104, 2015 | 534* | 2015 |
| Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment Z Ju, H Jiang, M Jaworski, C Rathinam, A Gompf, C Klein, A Trumpp, ... Nature medicine 13 (6), 742-747, 2007 | 330 | 2007 |
| Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo A Rongvaux, T Willinger, H Takizawa, C Rathinam, W Auerbach, ... Proceedings of the National Academy of Sciences 108 (6), 2378-2383, 2011 | 290 | 2011 |
| Humanized mice for modeling human infectious disease: challenges, progress, and outlook N Legrand, A Ploss, R Balling, PD Becker, C Borsotti, N Brezillon, ... Cell host & microbe 6 (1), 5-9, 2009 | 271 | 2009 |
| Transgenic expression of human signal regulatory protein alpha in Rag2−/− γc−/− mice improves engraftment of human hematopoietic cells in humanized mice T Strowig, A Rongvaux, C Rathinam, H Takizawa, C Borsotti, W Philbrick, ... Proceedings of the National Academy of Sciences 108 (32), 13218-13223, 2011 | 269 | 2011 |
| Memory/effector (CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology M Kamanaka, S Huber, LA Zenewicz, N Gagliani, C Rathinam, ... Journal of Experimental Medicine 208 (5), 1027-1040, 2011 | 227 | 2011 |
| A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14 G Bohn, A Allroth, G Brandes, J Thiel, E Glocker, AA Schäffer, C Rathinam, ... Nature medicine 13 (1), 38-45, 2007 | 220 | 2007 |
| Efficient differentiation and function of human macrophages in humanized CSF-1 mice C Rathinam, WT Poueymirou, J Rojas, AJ Murphy, DM Valenzuela, ... Blood, The Journal of the American Society of Hematology 118 (11), 3119-3128, 2011 | 190 | 2011 |
| The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation N Ahmed, M Zeng, I Sinha, L Polin, WZ Wei, C Rathinam, R Flavell, ... Nature immunology 12 (12), 1176-1183, 2011 | 175 | 2011 |
| The deubiquitinase activity of A 20 is dispensable for NF‐κ B signaling A De, T Dainichi, CV Rathinam, S Ghosh EMBO reports 15 (7), 775-783, 2014 | 144 | 2014 |
| The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells C Rathinam, CBF Thien, WY Langdon, H Gu, RA Flavell Genes & development 22 (8), 992-997, 2008 | 139 | 2008 |
| The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function C Rathinam, R Geffers, R Yücel, J Buer, K Welte, T Möröy, C Klein Immunity 22 (6), 717-728, 2005 | 137 | 2005 |
| Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2 J Jung, G Bohn, A Allroth, K Boztug, G Brandes, I Sandrock, AA Schäffer, ... Blood 108 (1), 362-369, 2006 | 132 | 2006 |
| Myeloid leukemia development in c-Cbl RING finger mutant mice is dependent on FLT3 signaling C Rathinam, CBF Thien, RA Flavell, WY Langdon Cancer cell 18 (4), 341-352, 2010 | 116 | 2010 |
| E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance MA Kriegel, C Rathinam, RA Flavell Proceedings of the National Academy of Sciences 106 (39), 16770-16775, 2009 | 95 | 2009 |
| The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells C Rathinam, LE Matesic, RA Flavell Nature immunology 12 (5), 399-407, 2011 | 93 | 2011 |
| Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells MA Kriegel, C Rathinam, RA Flavell Proceedings of the National Academy of Sciences 109 (9), 3457-3462, 2012 | 73 | 2012 |
| Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence MM Nakagawa, K Thummar, J Mandelbaum, L Pasqualucci, CV Rathinam Journal of Experimental Medicine 212 (2), 203-216, 2015 | 48 | 2015 |
