Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA W Yu, D Gius, P Onyango, K Muldoon-Jacobs, J Karp, AP Feinberg, H Cui Nature 451 (7175), 202-206, 2008 | 1031 | 2008 |
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, N Aykin-Burns, ... Cancer cell 17 (1), 41-52, 2010 | 901 | 2010 |
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression KM Jacobs, JD Pennington, KS Bisht, N Aykin-Burns, HS Kim, M Mishra, ... International journal of biological sciences 4 (5), 291, 2008 | 304 | 2008 |
The 9-Å solution: How mRNA pseudoknots promote efficient programmed− 1 ribosomal frameshifting EP Plant, KLM Jacobs, JW Harger, A Meskauskas, JL Jacobs, JL Baxter, ... Rna 9 (2), 168-174, 2003 | 193 | 2003 |
Epigenetic targets of some toxicologically relevant metals: a review of the literature TF Cheng, S Choudhuri, K Muldoon‐Jacobs Journal of Applied Toxicology 32 (9), 643-653, 2012 | 187 | 2012 |
United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts HA Oketch-Rabah, AL Roe, CV Rider, HL Bonkovsky, GI Giancaspro, ... Toxicology reports 7, 386-402, 2020 | 150 | 2020 |
Thresholds of Toxicological Concern for cosmetics-related substances: New database, thresholds, and enrichment of chemical space C Yang, SM Barlow, KLM Jacobs, V Vitcheva, AR Boobis, SP Felter, ... Food and Chemical Toxicology 109, 170-193, 2017 | 96 | 2017 |
Thioredoxin and thioredoxin reductase as redox-sensitive molecular targets for cancer therapy JD Pennington, KM Jacobs, L Sun, G Bar-Sela, M Mishra, D Gius Current pharmaceutical design 13 (33), 3368-3377, 2007 | 77 | 2007 |
A proposed method to predict preterm birth using clinical data, standard maternal serum screening, and cholesterol BW Alleman, AR Smith, HM Byers, B Bedell, KK Ryckman, JC Murray, ... American journal of obstetrics and gynecology 208 (6), 472. e1-472. e11, 2013 | 72 | 2013 |
Decreased peptidyltransferase activity correlates with increased programmed− 1 ribosomal frameshifting and viral maintenance defects in the yeast Saccharomyces cerevisiae A Meskauskas, JW Harger, KLM Jacobs, JD Dinman Rna 9 (8), 982-992, 2003 | 56 | 2003 |
DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells MV Mishra, KS Bisht, L Sun, K Muldoon-Jacobs, R Awwad, A Kaushal, ... Molecular Cancer Research 6 (2), 243-249, 2008 | 54 | 2008 |
Infant toxicology: state of the science and considerations in evaluation of safety A Neal-Kluever, J Aungst, Y Gu, K Hatwell, K Muldoon-Jacobs, A Liem, ... Food and Chemical Toxicology 70, 68-83, 2014 | 48 | 2014 |
Specific effects of ribosome-tethered molecular chaperones on programmed− 1 ribosomal frameshifting KL Muldoon-Jacobs, JD Dinman Eukaryotic Cell 5 (4), 762-770, 2006 | 37 | 2006 |
Regulatory use of computational toxicology tools and databases at the United States Food and Drug Administration's Office of Food Additive Safety KB Arvidson, R Chanderbhan, K Muldoon-Jacobs, J Mayer, ... Expert opinion on drug metabolism & toxicology 6 (7), 793-796, 2010 | 27 | 2010 |
Histone deacetylase inhibitor and demethylating agent chromatin compaction and the radiation response by cancer cells G Bar-Sela, KM Jacobs, D Gius The Cancer Journal 13 (1), 65-69, 2007 | 25 | 2007 |
A new paradigm in threshold of toxicological concern based on chemoinformatics analysis of a highly curated database enriched with antimicrobials C Yang, M Cheeseman, J Rathman, A Mostrag, N Skoulis, V Vitcheva, ... Food and Chemical Toxicology 143, 111561, 2020 | 17 | 2020 |
Cardiomyocyte-specific JunD overexpression increases infarct size following ischemia/reperfusion cardiac injury by downregulating Sirt3 A Akhmedov, F Montecucco, S Costantino, D Vdovenko, AS Clerigué, ... Thrombosis and haemostasis 120 (01), 168-180, 2020 | 17 | 2020 |
COSMOS next generation–A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals C Yang, MTD Cronin, KB Arvidson, B Bienfait, SJ Enoch, B Heldreth, ... Computational Toxicology 19, 100175, 2021 | 16 | 2021 |
Challenges and opportunities for improving the safety assessment of botanical dietary supplements: a United States Pharmacopeia Perspective HA Oketch‐Rabah, AL Roe, K Muldoon‐Jacobs, GI Giancaspro Clinical Pharmacology & Therapeutics 104 (3), 426-429, 2018 | 14 | 2018 |
Review of the oral toxicity of cannabidiol (CBD) J Gingrich, S Choudhuri, P Cournoyer, J Downey, KM Jacobs Food and Chemical Toxicology, 113799, 2023 | 10 | 2023 |