| A large-scale evaluation of computational protein function prediction P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ... Nature methods 10 (3), 221-227, 2013 | 1150 | 2013 |
| BODIL: a molecular modeling environment for structure-function analysis and drug design JV Lehtonen, DJ Still, V Rantanen, J Ekholm, D Björklund, Z Iftikhar, ... Journal of computer-aided molecular design 18, 401-419, 2004 | 253 | 2004 |
| Association of gut microbiota with post-operative clinical course in Crohn’s disease N Dey, DAW Soergel, S Repo, SE Brenner BMC gastroenterology 13, 1-11, 2013 | 157 | 2013 |
| Somatic mutations of ErbB4: selective loss-of-function phenotype affecting signal transduction pathways in cancer D Tvorogov, M Sundvall, K Kurppa, M Hollmén, S Repo, MS Johnson, ... Journal of Biological Chemistry 284 (9), 5582-5591, 2009 | 89 | 2009 |
| Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex allergy by comutation of six amino acid residues on the conformational IgE epitopes P Karisola, J Mikkola, N Kalkkinen, KJ Airenne, OH Laitinen, S Repo, ... The Journal of Immunology 172 (4), 2621-2628, 2004 | 68 | 2004 |
| ELIXIR: providing a sustainable infrastructure for life science data at European scale J Harrow, R Drysdale, A Smith, S Repo, J Lanfear, N Blomberg Bioinformatics 37 (16), 2506-2511, 2021 | 60 | 2021 |
| Binding properties of HABA-type azo derivatives to avidin and avidin-related protein 4 S Repo, TA Paldanius, VP Hytönen, TKM Nyholm, KK Halling, ... Chemistry & biology 13 (10), 1029-1039, 2006 | 60 | 2006 |
| Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges R Daneshjou, Y Wang, Y Bromberg, S Bovo, PL Martelli, G Babbi, ... Human mutation 38 (9), 1182-1192, 2017 | 48 | 2017 |
| Functional classification of amino acid decarboxylases from the alanine racemase structural family by phylogenetic studies H Kidron, S Repo, MS Johnson, TA Salminen Molecular biology and evolution 24 (1), 79-89, 2007 | 45 | 2007 |
| Reports from CAGI: the critical assessment of genome interpretation RA Hoskins, S Repo, D Barsky, G Andreoletti, J Moult, SE Brenner Human mutation 38 (9), 1039, 2017 | 44 | 2017 |
| The major conformational IgE-binding epitopes of hevein (Hev b6. 02) are identified by a novel chimera-based allergen epitope mapping strategy P Karisola, H Alenius, J Mikkola, N Kalkkinen, J Helin, OT Pentikäinen, ... Journal of Biological Chemistry 277 (25), 22656-22661, 2002 | 44 | 2002 |
| CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods Genome biology 25 (1), 53, 2024 | 33 | 2024 |
| Phylogenetic molecular function annotation BE Engelhardt, MI Jordan, ST Repo, SE Brenner Journal of Physics: Conference Series 180 (1), 012024, 2009 | 19 | 2009 |
| Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges B Cai, B Li, N Kiga, J Thusberg, T Bergquist, YC Chen, N Niknafs, ... Human mutation 38 (9), 1266-1276, 2017 | 18 | 2017 |
| Ligand specificity of constitutive androstane receptor as probed by induced-fit docking and mutagenesis S Repo, J Jyrkkarinne, JT Pulkkinen, R Laatikainen, P Honkakoski, ... Journal of medicinal chemistry 51 (22), 7119-7131, 2008 | 18 | 2008 |
| Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI M Carraro, G Minervini, M Giollo, Y Bromberg, E Capriotti, R Casadio, ... Human mutation 38 (9), 1042-1050, 2017 | 17 | 2017 |
| Demonstrating public value to funders and other stakeholders—the journey of ELIXIR, a virtual and distributed research infrastructure for life science data CS Martin, S Repo, J Arenas Márquez, N Blomberg, KB Lauer, ... Annals of Public and Cooperative Economics 92 (3), 497-510, 2021 | 13 | 2021 |
| Systematically linking tranSMART, Galaxy and EGA for reusing human translational research data C Zhang, J Bijlard, C Staiger, S Scollen, D van Enckevort, Y Hoogstrate, ... F1000Research 6, ELIXIR-1488, 2017 | 11 | 2017 |
| Integration of EGA secure data access into Galaxy Y Hoogstrate, C Zhang, A Senf, J Bijlard, S Hiltemann, D van Enckevort, ... F1000Research 5, ELIXIR-2841, 2016 | 10 | 2016 |
| Assessing computational predictions of the phenotypic effect of cystathionine‐beta‐synthase variants L Kasak, C Bakolitsa, Z Hu, C Yu, J Rine, DF Dimster‐Denk, G Pandey, ... Human mutation 40 (9), 1530-1545, 2019 | 8 | 2019 |
