Horizontal gene transfer can rescue prokaryotes from Muller’s ratchet: benefit of DNA from dead cells and population subdivision N Takeuchi, K Kaneko, EV Koonin G3: Genes, Genomes, Genetics 4 (2), 325-339, 2014 | 132 | 2014 |
Multilevel selection in models of prebiotic evolution: compartments and spatial self-organization P Hogeweg, N Takeuchi Origins of Life and Evolution of the Biosphere 33, 375-403, 2003 | 132 | 2003 |
Nature and intensity of selection pressure on CRISPR-associated genes N Takeuchi, YI Wolf, KS Makarova, EV Koonin Journal of bacteriology 194 (5), 1216-1225, 2012 | 124 | 2012 |
Evolutionary dynamics of RNA-like replicator systems: a bioinformatic approach to the origin of life N Takeuchi, P Hogeweg Physics of Life Reviews 9 (3), 219-263, 2012 | 111 | 2012 |
Multilevel selection in models of prebiotic evolution II: a direct comparison of compartmentalization and spatial self-organization N Takeuchi, P Hogeweg PLoS computational biology 5 (10), e1000542, 2009 | 108 | 2009 |
Error-threshold exists in fitness landscapes with lethal mutants N Takeuchi, P Hogeweg BMC Evolutionary Biology 7, 1-12, 2007 | 82 | 2007 |
On the origin of DNA genomes: evolution of the division of labor between template and catalyst in model replicator systems N Takeuchi, P Hogeweg, EV Koonin PLoS computational biology 7 (3), e1002024, 2011 | 75 | 2011 |
Evolution of complexity in RNA-like replicator systems N Takeuchi, P Hogeweg Biology Direct 3, 1-20, 2008 | 75 | 2008 |
Phenotypic error threshold; additivity and epistasis in RNA evolution N Takeuchi, PH Poorthuis, P Hogeweg BMC Evolutionary Biology 5, 1-9, 2005 | 71 | 2005 |
Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection N Takeuchi, OX Cordero, EV Koonin, K Kaneko BMC biology 13, 1-11, 2015 | 48 | 2015 |
The origin of a primordial genome through spontaneous symmetry breaking N Takeuchi, P Hogeweg, K Kaneko Nature communications 8 (1), 250, 2017 | 41 | 2017 |
The role of complex formation and deleterious mutations for the stability of RNA-like replicator systems N Takeuchi, P Hogeweg Journal of molecular evolution 65, 668-686, 2007 | 40 | 2007 |
Slightly beneficial genes are retained by bacteria evolving DNA uptake despite selfish elements B van Dijk, P Hogeweg, HM Doekes, N Takeuchi Elife 9, e56801, 2020 | 35 | 2020 |
The origin of the central dogma through conflicting multilevel selection N Takeuchi, K Kaneko Proceedings of the Royal Society B 286, 20191359, 2019 | 17 | 2019 |
Conceptualizing the origin of life in terms of evolution N Takeuchi, P Hogeweg, K Kaneko Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2017 | 17 | 2017 |
Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population N Takeuchi, K Kaneko, P Hogeweg Proceedings of the Royal Society B: Biological Sciences 283 (1830), 20153109, 2016 | 17 | 2016 |
The evolution of strand preference in simulated RNA replicators with strand displacement: implications for the origin of transcription N Takeuchi, L Salazar, AM Poole, P Hogeweg Biology Direct 3, 1-22, 2008 | 17 | 2008 |
Stronger selection can slow down evolution driven by recombination on a smooth fitness landscape M Ueda, N Takeuchi, K Kaneko PLoS One 12 (8), e0183120, 2017 | 14 | 2017 |
Transposable elements promote the evolution of genome streamlining B van Dijk, F Bertels, L Stolk, N Takeuchi, PB Rainey Philosophical Transactions of the Royal Society B 377 (1842), 20200477, 2022 | 13 | 2022 |
A scaling law of multilevel evolution: how the balance between within-and among-collective evolution is determined N Takeuchi, N Mitarai, K Kaneko Genetics, 2021 | 5 | 2021 |