The phenobarbital response enhancer module in the human bilirubin UDP‐glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR J Sugatani, H Kojima, A Ueda, S Kakizaki, K Yoshinari, QH Gong, ... Hepatology 33 (5), 1232-1238, 2001 | 460 | 2001 |
Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia J Sugatani, K Yamakawa, K Yoshinari, T Machida, H Takagi, M Mori, ... Biochemical and biophysical research communications 292 (2), 492-497, 2002 | 271 | 2002 |
Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP … J Sugatani, S Nishitani, K Yamakawa, K Yoshinari, T Sueyoshi, M Negishi, ... Molecular pharmacology 67 (3), 845-855, 2005 | 229 | 2005 |
Estrogen Activation of the Nuclear Orphan Receptor CAR (Constitutive Active Receptor) in Induction of the Mouse Cyp2b10 Gene T Kawamoto, S Kakizaki, K Yoshinari, M Negishi Molecular endocrinology 14 (11), 1897-1905, 2000 | 214 | 2000 |
Identification of the nuclear receptor CAR: HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital K Yoshinari, K Kobayashi, R Moore, T Kawamoto, M Negishi FEBS letters 548 (1-3), 17-20, 2003 | 207 | 2003 |
Role of human hepatocyte nuclear factor 4α in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA Y Kamiyama, T Matsubara, K Yoshinari, K Nagata, H Kamimura, ... Drug metabolism and pharmacokinetics 22 (4), 287-298, 2007 | 169 | 2007 |
The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics J Sugatani, K Yamakawa, E Tonda, S Nishitani, K Yoshinari, M Degawa, ... Biochemical pharmacology 67 (5), 989-1000, 2004 | 145 | 2004 |
Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital H Xiong, K Yoshinari, KLR Brouwer, M Negishi Drug Metabolism and Disposition 30 (8), 918-923, 2002 | 129 | 2002 |
Profiling of bisphenol A and eight of its analogues on transcriptional activity via human nuclear receptors H Kojima, S Takeuchi, S Sanoh, K Okuda, S Kitamura, N Uramaru, ... Toxicology 413, 48-55, 2019 | 112 | 2019 |
Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYP2B1 gene by phenobarbital in rat livers K Yoshinari, T Sueyoshi, R Moore, M Negishi Molecular pharmacology 59 (2), 278-284, 2001 | 111 | 2001 |
Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5′-flanking region K Yoshinari, N Yoda, T Toriyabe, Y Yamazoe Biochemical pharmacology 79 (2), 261-269, 2010 | 106 | 2010 |
Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet K Yoshinari, S Takagi, T Yoshimasa, J Sugatani, M Miwa Pharmaceutical research 23, 1188-1200, 2006 | 89 | 2006 |
Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: association with the suppression of hepatic … J Sugatani, T Wada, M Osabe, K Yamakawa, K Yoshinari, M Miwa Drug Metabolism and Disposition 34 (10), 1677-1687, 2006 | 87 | 2006 |
Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements K Yoshinari, R Ueda, K Kusano, T Yoshimura, K Nagata, Y Yamazoe Biochemical pharmacology 76 (1), 139-145, 2008 | 82 | 2008 |
Role of vitamin D receptor in the lithocholic acid-mediated CYP3A induction in vitro and in vivo T Matsubara, K Yoshinari, K Aoyama, M Sugawara, Y Sekiya, K Nagata, ... Drug metabolism and disposition 36 (10), 2058-2063, 2008 | 81 | 2008 |
Fibroblast growth factor 19 treatment ameliorates disruption of hepatic lipid metabolism in farnesoid X receptor (Fxr)-null mice M Miyata, Y Sakaida, H Matsuzawa, K Yoshinari, Y Yamazoe Biological and Pharmaceutical Bulletin 34 (12), 1885-1889, 2011 | 78 | 2011 |
Changes in the expression of cytochromes P450 and nuclear receptors in the liver of genetically diabetic db/db mice K Yoshinari, S Takagi, J Sugatani, M Miwa Biological and Pharmaceutical Bulletin 29 (8), 1634-1638, 2006 | 74 | 2006 |
Crystal structure‐based studies of cytosolic sulfotransferase K Yoshinari, EV Petrotchenko, LC Pedersen, M Negishi Journal of biochemical and molecular toxicology 15 (2), 67-75, 2001 | 74 | 2001 |
Enzymatic characterization and interspecies difference of phenol sulfotransferases, ST1A forms W Honma, Y Kamiyama, K Yoshinari, H Sasano, M Shimada, K Nagata, ... Drug metabolism and disposition 29 (3), 274-281, 2001 | 66 | 2001 |
Involvement of Vitamin D receptor in the intestinal induction of human ABCB1 S Tachibana, K Yoshinari, T Chikada, T Toriyabe, K Nagata, Y Yamazoe Drug metabolism and disposition 37 (8), 1604-1610, 2009 | 65 | 2009 |