| Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: a positron emission tomographic functional magnetic resonance imaging study M Slifstein, E Van De Giessen, J Van Snellenberg, JL Thompson, ... JAMA psychiatry 72 (4), 316-324, 2015 | 413 | 2015 |
| Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy LS Kegeles, X Mao, AD Stanford, R Girgis, N Ojeil, X Xu, R Gil, M Slifstein, ... Archives of general psychiatry 69 (5), 449-459, 2012 | 346 | 2012 |
| Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention JA Lieberman, RR Girgis, G Brucato, H Moore, F Provenzano, L Kegeles, ... Molecular psychiatry 23 (8), 1764-1772, 2018 | 313 | 2018 |
| Imaging glutamate in schizophrenia: review of findings and implications for drug discovery EMP Poels, LS Kegeles, JT Kantrowitz, M Slifstein, DC Javitt, ... Molecular psychiatry 19 (1), 20-29, 2014 | 242 | 2014 |
| A randomized exploratory trial of an alpha-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia JA Lieberman, G Dunbar, AC Segreti, RR Girgis, F Seoane, JS Beaver, ... Neuropsychopharmacology 38 (6), 968-975, 2013 | 212 | 2013 |
| The long-term effects of antipsychotic medication on clinical course in schizophrenia DC Goff, P Falkai, WW Fleischhacker, RR Girgis, RM Kahn, H Uchida, ... American Journal of Psychiatry 174 (9), 840-849, 2017 | 210 | 2017 |
| Signaling pathways in schizophrenia: emerging targets and therapeutic strategies CS Karam, JS Ballon, NM Bivens, Z Freyberg, RR Girgis, JE Lizardi-Ortiz, ... Trends in pharmacological sciences 31 (8), 381-390, 2010 | 206 | 2010 |
| Glutamatergic abnormalities in schizophrenia: a review of proton MRS findings EMP Poels, LS Kegeles, JT Kantrowitz, DC Javitt, JA Lieberman, ... Schizophrenia research 152 (2-3), 325-332, 2014 | 191 | 2014 |
| Novel dopamine therapeutics for cognitive deficits in schizophrenia AFT Arnsten, RR Girgis, DL Gray, RB Mailman Biological psychiatry 81 (1), 67-77, 2017 | 168 | 2017 |
| Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain CM Cassidy, FA Zucca, RR Girgis, SC Baker, JJ Weinstein, ME Sharp, ... Proceedings of the National Academy of Sciences 116 (11), 5108-5117, 2019 | 166 | 2019 |
| The cytokine model of schizophrenia: emerging therapeutic strategies RR Girgis, SS Kumar, AS Brown Biological psychiatry 75 (4), 292-299, 2014 | 158 | 2014 |
| Dopamine release in chronic cannabis users: a [11c] raclopride positron emission tomography study NBL Urban, M Slifstein, JL Thompson, X Xu, RR Girgis, S Raheja, ... Biological psychiatry 71 (8), 677-683, 2012 | 145 | 2012 |
| Early detection and preventive intervention in schizophrenia: from fantasy to reality JA Lieberman, SA Small, RR Girgis American Journal of Psychiatry 176 (10), 794-810, 2019 | 141 | 2019 |
| Volumetric alterations of the orbitofrontal cortex in autism RR Girgis, NJ Minshew, NM Melhem, JJ Nutche, MS Keshavan, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 31 (1), 41-45, 2007 | 136 | 2007 |
| Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway RR Girgis, JA Javitch, JA Lieberman Molecular psychiatry 13 (10), 918-929, 2008 | 132 | 2008 |
| Mechanisms of working memory impairment in schizophrenia JX Van Snellenberg, RR Girgis, G Horga, E van de Giessen, M Slifstein, ... Biological psychiatry 80 (8), 617-626, 2016 | 130 | 2016 |
| Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO RR Girgis, M Slifstein, D D’Souza, Y Lee, A Periclou, P Ghahramani, ... Psychopharmacology 233, 3503-3512, 2016 | 123 | 2016 |
| Clozapine v. chlorpromazine in treatment-naive, first-episode schizophrenia: 9-year outcomes of a randomised clinical trial RR Girgis, MR Phillips, X Li, K Li, H Jiang, C Wu, N Duan, Y Niu, ... The British Journal of Psychiatry 199 (4), 281-288, 2011 | 120 | 2011 |
| Effects of the D1 dopamine receptor agonist dihydrexidine (DAR-0100A) on working memory in schizotypal personality disorder DR Rosell, LC Zaluda, MM McClure, MM Perez-Rodriguez, KS Strike, ... Neuropsychopharmacology 40 (2), 446-453, 2015 | 111 | 2015 |
| Striatal dopamine release in schizophrenia comorbid with substance dependence JL Thompson, N Urban, M Slifstein, X Xu, LS Kegeles, RR Girgis, ... Molecular psychiatry 18 (8), 909-915, 2013 | 108 | 2013 |
