フォロー
TW Randolph
TW Randolph
Department of Chemical and Biological Engineering, University of Colorado, Boulder
確認したメール アドレス: colorado.edu
タイトル
引用先
引用先
Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation
EY Chi, S Krishnan, TW Randolph, JF Carpenter
Pharmaceutical research 20 (9), 1325-1336, 2003
17422003
Rational design of stable lyophilized protein formulations: some practical advice
JF Carpenter, MJ Pikal, BS Chang, TW Randolph
Pharmaceutical research 14 (8), 969, 1997
10211997
Water in Carbon-Dioxide Microemulsions-An Environment for Hydrophiles Including Proteins
KP Johnston, KL Harrison, MJ Clarke, SM Howdle, MP Heitz, FV Bright, ...
Science 271 (5249), 624-626, 1996
7951996
Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding
SD Allison, B Chang, TW Randolph, JF Carpenter
Archives of Biochemistry and Biophysics 365 (2), 289-298, 1999
7071999
Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality
JF Carpenter, TW Randolph, WIM Jiskoot, DJA Crommelin, CR Middaugh, ...
Journal of pharmaceutical sciences 98 (4), 1201-1205, 2008
6372008
The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature‐controlled shelf
JA Searles, JF Carpenter, TW Randolph
Journal of pharmaceutical sciences 90 (7), 860-871, 2001
4902001
Rational design of stable lyophilized protein formulations: theory and practice
JF Carpenter, BS Chang, W Garzon-Rodriguez, TW Randolph
Rational Design of Stable Protein Formulations, 109-133, 2002
4342002
Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor
EY Chi, S Krishnan, BS Kendrick, BS Chang, JF Carpenter, TW Randolph
Protein science 12 (5), 903-913, 2009
4292009
Tween protects recombinant human growth hormone against agitation‐induced damage via hydrophobic interactions
NB Bam, JL Cleland, J Yang, MC Manning, JF Carpenter, RF Kelley, ...
Journal of pharmaceutical sciences 87 (12), 1554-1559, 1998
3881998
Annealing to optimize the primary drying rate, reduce freezing‐induced drying rate heterogeneity, and determine Tg′ in pharmaceutical lyophilization
JA Searles, JF Carpenter, TW Randolph
Journal of pharmaceutical sciences 90 (7), 872-887, 2001
3832001
Effects of Tween 20® and Tween 80® on the stability of Albutropin during agitation
DK Chou, R Krishnamurthy, TW Randolph, JF Carpenter, MC Manning
Journal of pharmaceutical sciences 94 (6), 1368-1381, 2005
3742005
Enzymatic catalysis in a supercritical fluid
TW Randolph, HW Blanch, JM Prausnitz, CR Wilke
Biotechnology letters 7 (5), 325-328, 1985
3491985
Sub-micrometer-sized biodegradable particles of poly (L-lactic acid) via the gas antisolvent spray precipitation process
TW Randolph, AD Randolph, M Mebes, S Yeung
Biotechnology Progress 9 (4), 429-435, 1993
3451993
Silicone oil-and agitation-induced aggregation of a monoclonal antibody in aqueous solution
R Thirumangalathu, S Krishnan, MS Ricci, DN Brems, TW Randolph, ...
Journal of pharmaceutical sciences 98 (9), 3167-3181, 2009
3192009
Effect of Tween 20 on freeze‐thawing‐and agitation‐induced aggregation of recombinant human factor XIII
L Krielgaard, LS Jones, TW Randolph, S Frokjaer, JM Flink, MC Manning, ...
Journal of pharmaceutical sciences 87 (12), 1593-1603, 1998
2951998
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release
W Jiskoot, TW Randolph, DB Volkin, CR Middaugh, C Schöneich, ...
Journal of pharmaceutical sciences 101 (3), 946-954, 2012
2922012
Solubilization of Pharmaceutical Substances in an Organic Solvent and Preparation of Pharmaceutical Powders Using the Same
MC Manning, TW Randolph, E Shefter, RF Falk
US Patent 5,981,474, 1999
2891999
Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native state
BS Kendrick, BS Chang, T Arakawa, B Peterson, TW Randolph, ...
Proceedings of the National Academy of Sciences 94 (22), 11917-11922, 1997
2731997
Sustained-release composition including amorphous polymer
TW Randolph, MC Manning, RF Falk
US Patent 6,613,358, 2003
2612003
Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis
S Krishnan, Y Eva, SJ Wood, BS Kendrick, C Li, W Garzon-Rodriguez, ...
Biochemistry 42 (3), 829-837, 2003
2572003
現在システムで処理を実行できません。しばらくしてからもう一度お試しください。
論文 1–20