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Gabrielle Fredman
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Infection regulates pro-resolving mediators that lower antibiotic requirements
N Chiang, G Fredman, F Bäckhed, SF Oh, T Vickery, BA Schmidt, ...
Nature 484 (7395), 524-528, 2012
7122012
Inflammation and its resolution as determinants of acute coronary syndromes
P Libby, I Tabas, G Fredman, EA Fisher
Circulation research 114 (12), 1867-1879, 2014
6662014
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
A Ariel, G Fredman, YP Sun, A Kantarci, TE Van Dyke, AD Luster, ...
Nature immunology 7 (11), 1209-1216, 2006
4562006
Resolvin D series and protectin D1 mitigate acute kidney injury
JS Duffield, S Hong, VS Vaidya, Y Lu, G Fredman, CN Serhan, ...
The Journal of Immunology 177 (9), 5902-5911, 2006
4402006
An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques
G Fredman, J Hellmann, JD Proto, G Kuriakose, RA Colas, B Dorweiler, ...
Nature communications 7 (1), 12859, 2016
3962016
Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice
G Fredman, N Kamaly, S Spolitu, J Milton, D Ghorpade, R Chiasson, ...
Science translational medicine 7 (275), 275ra20-275ra20, 2015
3602015
MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits
A Recchiuti, S Krishnamoorthy, G Fredman, N Chiang, CN Serhan
The FASEB Journal 25 (2), 544, 2011
3382011
Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair
G Leoni, PA Neumann, N Kamaly, M Quiros, H Nishio, HR Jones, ...
The Journal of clinical investigation 125 (3), 1215-1227, 2015
3212015
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs
S Krishnamoorthy, A Recchiuti, N Chiang, G Fredman, CN Serhan
The American journal of pathology 180 (5), 2018-2027, 2012
3042012
Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets
M Dona, G Fredman, JM Schwab, N Chiang, M Arita, A Goodarzi, ...
Blood, The Journal of the American Society of Hematology 112 (3), 848-855, 2008
2952008
The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering
A Ariel, PL Li, W Wang, WX Tang, G Fredman, S Hong, KH Gotlinger, ...
Journal of Biological Chemistry 280 (52), 43079-43086, 2005
2892005
Mechanisms and consequences of defective efferocytosis in atherosclerosis
A Yurdagul Jr, AC Doran, B Cai, G Fredman, IA Tabas
Frontiers in cardiovascular medicine 4, 86, 2018
2802018
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles
N Kamaly, G Fredman, M Subramanian, S Gadde, A Pesic, L Cheung, ...
Proceedings of the National Academy of Sciences 110 (16), 6506-6511, 2013
2402013
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis
B Cai, EB Thorp, AC Doran, BE Sansbury, MJAP Daemen, B Dorweiler, ...
The Journal of clinical investigation 127 (2), 564-568, 2017
2162017
Resolvin E2 formation and impact in inflammation resolution
SF Oh, M Dona, G Fredman, S Krishnamoorthy, D Irimia, CN Serhan
The Journal of Immunology 188 (9), 4527-4534, 2012
2122012
Targeted interleukin-10 nanotherapeutics developed with a microfluidic chip enhance resolution of inflammation in advanced atherosclerosis
N Kamaly, G Fredman, JJR Fojas, M Subramanian, WII Choi, K Zepeda, ...
ACS nano 10 (5), 5280-5292, 2016
2082016
Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway
G Fredman, L Ozcan, S Spolitu, J Hellmann, M Spite, J Backs, I Tabas
Proceedings of the National Academy of Sciences 111 (40), 14530-14535, 2014
2062014
Boosting inflammation resolution in atherosclerosis: the next frontier for therapy
G Fredman, I Tabas
The American journal of pathology 187 (6), 1211-1221, 2017
2022017
Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution
G Fredman, CN Serhan
Biochemical Journal 437 (2), 185-197, 2011
2002011
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
B Cai, EB Thorp, AC Doran, M Subramanian, BE Sansbury, CS Lin, ...
Proceedings of the National Academy of Sciences 113 (23), 6526-6531, 2016
1992016
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