| The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities J Lewerenz, SJ Hewett, Y Huang, M Lambros, PW Gout, PW Kalivas, ... Antioxidants & redox signaling 18 (5), 522-555, 2013 | 861 | 2013 |
| Mechanisms of the antioxidant effects of nitric oxide DA Wink, KM Miranda, MG Espey, RM Pluta, SJ Hewett, C Colton, M Vitek, ... Antioxidants and redox signaling 3 (2), 203-213, 2001 | 470 | 2001 |
| Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS SI Hewett, CA Csernansky, DW Choi Neuron 13 (2), 487-494, 1994 | 381 | 1994 |
| Cyclooxygenase-2 contributes toN-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture SJ Hewett, TF Uliasz, AS Vidwans, JA Hewett Journal of Pharmacology and Experimental Therapeutics 293 (2), 417-425, 2000 | 287 | 2000 |
| Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease RJ Ferrante, H Ryu, JK Kubilus, S D'Mello, KL Sugars, J Lee, P Lu, ... Journal of Neuroscience 24 (46), 10335-10342, 2004 | 213 | 2004 |
| Interleukin‐1β: a bridge between inflammation and excitotoxicity? B Fogal, SJ Hewett Journal of neurochemistry 106 (1), 1-23, 2008 | 180 | 2008 |
| Interleukin-1β in central nervous system injury and repair SJ Hewett, NA Jackman, RJ Claycomb European journal of neurodegenerative disease 1 (2), 195, 2012 | 167 | 2012 |
| System xc− activity and astrocytes are necessary for interleukin-1β-mediated hypoxic neuronal injury B Fogal, J Li, D Lobner, LD McCullough, SJ Hewett Journal of Neuroscience 27 (38), 10094-10105, 2007 | 146 | 2007 |
| A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture TF Uliasz, SJ Hewett Journal of neuroscience methods 100 (1-2), 157-163, 2000 | 141 | 2000 |
| Interferon-γ and interleukin-1β induce nitric oxide formation from primary mouse astrocytes SJ Hewett, JA Corbett, ML McDaniel, DW Choi Neuroscience letters 164 (1-2), 229-232, 1993 | 140 | 1993 |
| Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes ME Hamby, TF Uliasz, SJ Hewett, JA Hewett Journal of neuroscience methods 150 (1), 128-137, 2006 | 125 | 2006 |
| SIN‐1‐induced cytotoxicity in mixed cortical cell culture: peroxynitrite‐dependent and‐independent induction of excitotoxic cell death JL Trackey, TF Uliasz, SJ Hewett Journal of neurochemistry 79 (2), 445-455, 2001 | 118 | 2001 |
| Main path and byways: non‐vesicular glutamate release by system xc− as an important modifier of glutamatergic neurotransmission A Massie, S Boillee, S Hewett, L Knackstedt, J Lewerenz Journal of neurochemistry 135 (6), 1062-1079, 2015 | 113 | 2015 |
| Contributions of cyclooxygenase-2 to neuroplasticity and neuropathology of the central nervous system SJ Hewett, SC Bell, JA Hewett Pharmacology & therapeutics 112 (2), 335-357, 2006 | 103 | 2006 |
| Potentiation of oxygen-glucose deprivation–induced neuronal death after induction of iNOS SJ Hewett, JK Muir, D Lobner, A Symons, DW Choi Stroke 27 (9), 1586-1591, 1996 | 102 | 1996 |
| TGF‐β1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS‐2 ME Hamby, JA Hewett, SJ Hewett Glia 54 (6), 566-577, 2006 | 101 | 2006 |
| Influence of glutamate and GABA transport on brain excitatory/inhibitory balance SMS Sears, SJ Hewett Experimental Biology and Medicine 246 (9), 1069-1083, 2021 | 100 | 2021 |
| Regulation of System xc−Activity and Expression in Astrocytes by Interleukin‐1β: Implications for Hypoxic Neuronal Injury NA Jackman, TF Uliasz, JA Hewett, SJ Hewett Glia 58 (15), 1806-1815, 2010 | 93 | 2010 |
| Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems DD Thomas, KM Miranda, MG Espey, D Citrin, D Jourd'Heuil, N Paolocci, ... Methods in enzymology 359, 84-105, 2002 | 92 | 2002 |
| Inhibition of system Xc− transporter attenuates autoimmune inflammatory demyelination KS Evonuk, BJ Baker, RE Doyle, CE Moseley, CM Sestero, BP Johnston, ... The Journal of Immunology 195 (2), 450-463, 2015 | 89 | 2015 |
James A. HewettSyracuse UniversityVerified email at syr.edu
