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Alan Michael Pittman
Alan Michael Pittman
Lecturer in Genomics/Bioinformatics, St. Georges, University of London
Verified email at sgul.ac.uk - Homepage
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Year
Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism
DR Williams, R de Silva, DC Paviour, A Pittman, HC Watt, L Kilford, ...
Brain 128 (6), 1247-1258, 2005
8352005
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3
IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...
Nature genetics 40 (5), 623-630, 2008
6542008
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ...
Nature genetics 39 (11), 1315-1317, 2007
6102007
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
5882016
The expression of DJ‐1 (PARK7) in normal human CNS and idiopathic Parkinson’s disease
R Bandopadhyay, AE Kingsbury, MR Cookson, AR Reid, IM Evans, ...
Brain 127 (2), 420-430, 2004
5682004
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
JO Johnson, EP Pioro, A Boehringer, R Chia, H Feit, AE Renton, ...
Nature neuroscience 17 (5), 664-666, 2014
5152014
Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome
DR Williams, JL Holton, C Strand, A Pittman, R de Silva, AJ Lees, ...
Brain 130 (6), 1566-1576, 2007
4692007
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
MC Di Bernardo, D Crowther-Swanepoel, P Broderick, E Webb, G Sellick, ...
Nature genetics 40 (10), 1204-1210, 2008
4502008
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33
RS Houlston, J Cheadle, SE Dobbins, A Tenesa, AM Jones, K Howarth, ...
Nature genetics 42 (11), 973-977, 2010
4252010
Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability
C Shaw-Smith, AM Pittman, L Willatt, H Martin, L Rickman, S Gribble, ...
Nature genetics 38 (9), 1032-1037, 2006
4212006
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13. 3 influence colorectal cancer risk
E Jaeger, E Webb, K Howarth, L Carvajal-Carmona, A Rowan, ...
Nature genetics 40 (1), 26-28, 2008
3522008
Detection of long repeat expansions from PCR-free whole-genome sequence data
E Dolzhenko, JJ Van Vugt, RJ Shaw, MA Bekritsky, M Van Blitterswijk, ...
Genome research 27 (11), 1895-1903, 2017
3182017
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
AM Pittman, AJ Myers, P Abou-Sleiman, HC Fung, M Kaleem, L Marlowe, ...
Journal of medical genetics 42 (11), 837-846, 2005
3062005
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
AJ Myers, AM Pittman, AS Zhao, K Rohrer, M Kaleem, L Marlowe, A Lees, ...
Neurobiology of disease 25 (3), 561-570, 2007
2742007
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
AJ Myers, M Kaleem, L Marlowe, AM Pittman, AJ Lees, HC Fung, ...
Human molecular genetics 14 (16), 2399-2404, 2005
2712005
Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
L Al-Olabi, S Polubothu, K Dowsett, KA Andrews, P Stadnik, AP Joseph, ...
The Journal of clinical investigation 128 (4), 1496-1508, 2018
2542018
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
D Trabzuni, S Wray, J Vandrovcova, A Ramasamy, R Walker, C Smith, ...
Human molecular genetics 21 (18), 4094-4103, 2012
2542012
Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer
IPM Tomlinson, LG Carvajal-Carmona, SE Dobbins, A Tenesa, AM Jones, ...
PLoS genetics 7 (6), e1002105, 2011
2402011
Genetic and phenotypic characterization of complex hereditary spastic paraplegia
E Kara, A Tucci, C Manzoni, DS Lynch, M Elpidorou, C Bettencourt, ...
Brain 139 (7), 1904-1918, 2016
2142016
Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia
E Meyer, KJ Carss, J Rankin, JME Nichols, D Grozeva, AP Joseph, ...
Nature genetics 49 (2), 223-237, 2017
2122017
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