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Heather A. McCauley
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Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids
R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ...
Cell metabolism 30 (2), 374-384. e6, 2019
3692019
Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
HA McCauley, JM Wells
Development 144 (6), 958-962, 2017
2842017
Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia
HA McCauley, G Guasch
Trends in molecular medicine 21 (8), 492-503, 2015
2082015
Human stomach-on-a-chip with luminal flow and peristaltic-like motility
KK Lee, HA McCauley, TR Broda, MJ Kofron, JM Wells, CI Hong
Lab on a Chip 18 (20), 3079-3085, 2018
932018
TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium
HA McCauley, CY Liu, AC Attia, KA Wikenheiser-Brokamp, Y Zhang, ...
Development 141 (23), 4628-4639, 2014
552014
A comprehensive structure-function study of neurogenin3 disease-causing alleles during human pancreas and intestinal organoid development
X Zhang, PS McGrath, J Salomone, M Rahal, HA McCauley, J Schweitzer, ...
Developmental cell 50 (3), 367-380. e7, 2019
422019
Deriving functional human enteroendocrine cells from pluripotent stem cells
KL Sinagoga, HA McCauley, JO Múnera, NA Reynolds, JR Enriquez, ...
Development 145 (19), dev165795, 2018
402018
Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport
HA McCauley, AL Matthis, JR Enriquez, JT Nichol, JG Sanchez, WJ Stone, ...
Nature communications 11 (1), 4791, 2020
342020
Tissue responses to Shiga toxin in human intestinal organoids
S Pradhan, SS Karve, AA Weiss, J Hawkins, HM Poling, MA Helmrath, ...
Cellular and molecular gastroenterology and hepatology 10 (1), 171-190, 2020
332020
Enteroendocrine regulation of nutrient absorption
HA McCauley
The Journal of Nutrition 150 (1), 10-21, 2020
322020
Ontogeny and function of the circadian clock in intestinal organoids
AE Rosselot, M Park, M Kim, T Matsu‐Ura, G Wu, DE Flores, ...
The EMBO Journal 41 (2), e106973, 2022
262022
A dietary change to a high-fat diet initiates a rapid adaptation of the intestine
JR Enriquez, HA McCauley, KX Zhang, JG Sanchez, GT Kalin, RA Lang, ...
Cell reports 41 (7), 2022
232022
De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones
HA McCauley, V Chevrier, D Birnbaum, G Guasch
Elife 6, e22914, 2017
162017
Using Human Induced Pluripotent Stem Cell–Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations
M Krishnamurthy, DO Kechele, T Broda, X Zhang, JR Enriquez, ...
Gastroenterology 163 (4), 1053-1063. e7, 2022
112022
Serial orthotopic transplantation of epithelial tumors in single-cell suspension
HA McCauley, G Guasch
Stem Cell Niche: Methods and Protocols, 231-245, 2013
92013
Enteroendocrine cells protect the stem cell niche by regulating crypt metabolism in response to nutrients
HA McCauley, AM Riedman, JR Enriquez, X Zhang, ...
Cellular and Molecular Gastroenterology and Hepatology 15 (6), 1293-1310, 2023
72023
Sweet relief: Reprogramming gastric endocrine cells to make insulin
HA McCauley, JM Wells
Cell Stem Cell 18 (3), 295-297, 2016
52016
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
JO Múnera, DO Kechele, C Bouffi, N Qu, R Jing, P Maity, JR Enriquez, ...
Cell Stem Cell 30 (11), 1434-1451. e9, 2023
42023
Transplanted human intestinal organoids: a resource for modeling human intestinal development
A Singh, HM Poling, P Chaturvedi, K Thorner, N Sundaram, DO Kechele, ...
Development 150 (9), dev201416, 2023
32023
Generation of human intestinal organoids containing tissue-resident immune cells
K Tominaga, D Kechele, G Sanchez, H McCauley, J Enriquez, S Vales, ...
Inflammatory Bowel Diseases 28 (Supplement_1), S57-S57, 2022
32022
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