Prediction of ice crystal size distribution after freezing of pharmaceutical solutions A Arsiccio, AA Barresi, R Pisano Crystal Growth & Design 17 (9), 4573-4581, 2017 | 27 | 2017 |
Application of the quality by design approach to the freezing step of freeze-drying: building the design space A Arsiccio, R Pisano Journal of pharmaceutical sciences 107 (6), 1586-1596, 2018 | 24 | 2018 |
Measuring and predicting pore size distribution of freeze-dried solutions A Arsiccio, AC Sparavigna, R Pisano, AA Barresi Drying Technology 37 (4), 435-447, 2019 | 19 | 2019 |
Stability of proteins in carbohydrates and other additives during freezing: the human growth hormone as a case study A Arsiccio, R Pisano The Journal of Physical Chemistry B 121 (37), 8652-8660, 2017 | 19 | 2017 |
Vacuum Induced Surface Freezing as an effective method for improved inter-and intra-vial product homogeneity A Arsiccio, A Barresi, T De Beer, I Oddone, PJ Van Bockstal, R Pisano European Journal of Pharmaceutics and Biopharmaceutics 128, 210-219, 2018 | 16 | 2018 |
Achieving continuous manufacturing in lyophilization: Technologies and approaches R Pisano, A Arsiccio, LC Capozzi, BL Trout European Journal of Pharmaceutics and Biopharmaceutics 142, 265-279, 2019 | 14 | 2019 |
Tuning, measurement and prediction of the impact of freezing on product morphology: A step toward improved design of freeze-drying cycles R Pisano, A Arsiccio, K Nakagawa, AA Barresi Drying Technology 37 (5), 579-599, 2019 | 14 | 2019 |
Effect of surfactants on surface-induced denaturation of proteins: evidence of an orientation-dependent mechanism A Arsiccio, J McCarty, R Pisano, JE Shea The Journal of Physical Chemistry B 122 (49), 11390-11399, 2018 | 12 | 2018 |
Water entrapment and structure ordering as protection mechanisms for protein structural preservation A Arsiccio, R Pisano The Journal of chemical physics 148 (5), 055102, 2018 | 11 | 2018 |
Clarifying the role of cryo-and lyo-protectants in the biopreservation of proteins A Arsiccio, R Pisano Physical Chemistry Chemical Physics 20 (12), 8267-8277, 2018 | 10 | 2018 |
The ice-water interface and protein stability: a review A Arsiccio, R Pisano Journal of pharmaceutical sciences 109 (7), 2116-2130, 2020 | 9 | 2020 |
Considerations on protein stability during freezing and its impact on the freeze-drying cycle: a design space approach A Arsiccio, P Giorsello, L Marenco, R Pisano Journal of pharmaceutical sciences 109 (1), 464-475, 2020 | 9 | 2020 |
Vacuum-Induced Surface Freezing for the Freeze-Drying of the Human Growth Hormone: How Does Nucleation Control Affect Protein Stability? I Oddone, A Arsiccio, C Duru, K Malik, J Ferguson, R Pisano, ... Journal of pharmaceutical sciences 109 (1), 254-263, 2020 | 9 | 2020 |
Surfactants as stabilizers for biopharmaceuticals: an insight into the molecular mechanisms for inhibition of protein aggregation A Arsiccio, R Pisano European Journal of Pharmaceutics and Biopharmaceutics 128, 98-106, 2018 | 9 | 2018 |
Heightened Cold-Denaturation of Proteins at the Ice–Water Interface A Arsiccio, J McCarty, R Pisano, JE Shea Journal of the American Chemical Society 142 (12), 5722-5730, 2020 | 8 | 2020 |
Designing the optimal formulation for biopharmaceuticals: a new approach combining molecular dynamics and experiments A Arsiccio, A Paladini, F Pattarino, R Pisano Journal of pharmaceutical sciences 108 (1), 431-438, 2019 | 5 | 2019 |
The preservation of lyophilized human growth hormone activity: how do buffers and sugars interact? A Arsiccio, R Pisano Pharmaceutical research 35 (7), 1-13, 2018 | 5 | 2018 |
Image Segmentation Applied to the Investigation of Craquelure Domains in Paintings A Arsiccio, AC Sparavigna, A Barresi EuroDrying'2019, 2019 | 2 | 2019 |
Image Segmentation and 3D reconstruction for improved prediction of the sublimation rate during freeze drying LC Capozzi, A Arsiccio, AC Sparavigna, R Pisano, AA Barresi IDS’2018–21st International Drying Symposium, 2018 | 2 | 2018 |
A model-based approach for the rational design of the freeze-thawing of a protein-based formulation A Arsiccio, L Marenco, R Pisano Pharmaceutical development and technology 25 (7), 823-831, 2020 | 1 | 2020 |