| Viruses and apoptosis A Roulston, RC Marcellus, PE Branton Annual Reviews in Microbiology 53 (1), 577-628, 1999 | 950 | 1999 |
| Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis M Nguyen, RC Marcellus, A Roulston, M Watson, L Serfass, ... Proceedings of the National Academy of Sciences 104 (49), 19512-19517, 2007 | 804 | 2007 |
| Characterization of a functional NF-κB site in the human interleukin 1β promoter: evidence for a positive autoregulatory loop J Hiscott, J Marois, J Garoufalis, M D'Addario, A Roulston, IVY Kwan, ... Molecular and cellular biology 13 (10), 6231-6240, 1993 | 804 | 1993 |
| Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor α A Roulston, C Reinhard, P Amiri, LT Williams Journal of Biological Chemistry 273 (17), 10232-10239, 1998 | 485 | 1998 |
| The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient … M Watson, A Roulston, L Bélec, X Billot, R Marcellus, D Bédard, C Bernier, ... Molecular and cellular biology 29 (21), 5872-5888, 2009 | 252 | 2009 |
| CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45 R Halenbeck, H MacDonald, A Roulston, TT Chen, L Conroy, LT Williams Current Biology 8 (9), 537-540, 1998 | 251 | 1998 |
| Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis N Lee, H MacDonald, C Reinhard, R Halenbeck, A Roulston, T Shi, ... Proceedings of the National Academy of Sciences 94 (25), 13642-13647, 1997 | 251 | 1997 |
| Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors A Roulston, R Lin, P Beauparlant, MA Wainberg, J Hiscott Microbiological reviews 59 (3), 481-505, 1995 | 203 | 1995 |
| Viral induction of the human beta interferon promoter: modulation of transcription by NF-kappa B/rel proteins and interferon regulatory factors E Garoufalis, I Kwan, R Lin, A Mustafa, N Pepin, A Roulston, J Lacoste, ... Journal of virology 68 (8), 4707-4715, 1994 | 117 | 1994 |
| Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777 P Beauparlant, D Bédard, C Bernier, H Chan, K Gilbert, D Goulet, ... Anti-cancer drugs 20 (5), 346-354, 2009 | 88 | 2009 |
| CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ... Nature 604 (7907), 749-756, 2022 | 84 | 2022 |
| Programming cancer cells for high expression levels of Mcl1 F Ertel, M Nguyen, A Roulston, GC Shore EMBO reports 14 (4), 328-336, 2013 | 84 | 2013 |
| Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo H Liu, D Su, J Zhang, S Ge, Y Li, F Wang, M Gravel, A Roulston, Q Song, ... Scientific Reports 7 (1), 8953, 2017 | 83 | 2017 |
| Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma F Robert, W Roman, A Bramoullé, C Fellmann, A Roulston, C Shustik, ... Proceedings of the National Academy of Sciences 111 (37), 13421-13426, 2014 | 69 | 2014 |
| New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology A Roulston, GC Shore Molecular & cellular oncology 3 (1), e1052180, 2016 | 64 | 2016 |
| Coordinate enhancement of cytokine gene expression in human immunodeficiency virus type 1-infected promonocytic cells M D'Addario, A Roulston, MA Wainberg, J Hiscott Journal of virology 64 (12), 6080-6089, 1990 | 59 | 1990 |
| Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells A Roulston, P Beauparlant, N Rice, J Hiscott Journal of virology 67 (9), 5235-5246, 1993 | 53 | 1993 |
| Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells. A Roulston, M D'addario, F Boulerice, S Caplan, MA Wainberg, J Hiscott The Journal of experimental medicine 175 (3), 751-763, 1992 | 51 | 1992 |
| Synergy between the NAMPT inhibitor GMX1777 (8) and pemetrexed in non–small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption M Chan, M Gravel, A Bramoullé, G Bridon, D Avizonis, GC Shore, ... Cancer research 74 (21), 5948-5954, 2014 | 49 | 2014 |
| The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity M Wieczorek, J Tcherkezian, C Bernier, AE Prota, S Chaaban, Y Rolland, ... Science translational medicine 8 (365), 365ra159-365ra159, 2016 | 47 | 2016 |
